Xenobiotica, Volume 53, Issue 10-11 (2023)

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Xenobiotica, Volume 53, Issue 10-11 (2023)

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General Xenobiochemistry

Article
Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol
Genki Ushirozako, Norie Murayama, Kyoko Tsukiyama-Kohara, Hiroshi Yamazaki & Yasuhiro Uno
Pages: 573-580
Published online: 19 Dec 2023
AbstractforTree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver
Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako, Tatsunori Masatani & Hiroshi Yamazaki
Pages: 581-586
Published online: 19 Dec 2023
AbstractforChronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver | Full Text | References | PDF (658.1 KB) | EPUB
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Article
Novel application of PBBM to justify impact of faster dissolution on safety and pharmacokinetics – a case study and utility in regulatory justifications
Rajkumar Boddu, Sivacharan Kollipara, Adithya Karthik Bhattiprolu & Tausif Ahmed
Pages: 587-602
Published online: 19 Dec 2023
AbstractforNovel application of PBBM to justify impact of faster dissolution on safety and pharmacokinetics – a case study and utility in regulatory justifications | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Clinical Pharmacokinetics and Metabolism

Article
Population pharmacokinetics of mycophenolic acid and dose optimisation in adult Chinese kidney transplant recipients
Kaisaner Rexiti, Xuehui Jiang, Ying Kong, Xu Chen, Hong Liu, Hongwei Peng & Xiaohua Wei
Pages: 603-612
Published online: 19 Dec 2023
AbstractforPopulation pharmacokinetics of mycophenolic acid and dose optimisation in adult Chinese kidney transplant recipients | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation
Takumi Tanaka, Shinji Kobuchi, Yukako Ito & Toshiyuki Sakaeda
Pages: 613-620
Published online: 19 Dec 2023
AbstractforPharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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