Channels, Volume 14, Issue 1 (2020)

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Channels, Volume 14, Issue 1 (2020)

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Review

Trafficking mechanisms underlying Nav channel subcellular localization in neurons
Laura Solé & Michael M. Tamkun
Pages: 1-17
Published online: 14 Dec 2019
AbstractforTrafficking mechanisms underlying Nav channel subcellular localization in neurons | Full Text | References | PDF (3.1 MB) | EPUB
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Article Commentary

Article Commentary
Bibliometric analysis of potassium channel research
Jingjing Shi, Shuqing Shi, Shuai Shi, Qiulei Jia, Guozhen Yuan, Yuguang Chu, Huan Wang, Yuanhui Hu & Hanming Cui
Pages: 18-27
Published online: 19 Dec 2019
AbstractforBibliometric analysis of potassium channel research | Full Text | References | PDF (2.9 MB) | EPUB
  • 3499 Views
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Research Article

Article
TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel
Marie-Christine Klein, Monika Lerner, Duy Nguyen, Stefan Pfeffer, Johanna Dudek, Friedrich Förster, Volkhard Helms, Sven Lang & Richard Zimmermann
Pages: 28-44
Published online: 11 Feb 2020
AbstractforTRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
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Brief Report

Brief Report
Flow fluorometry quantification of anion channel VRAC subunit LRRC8A at the membrane of living U937 cells
Valentina Yurinskaya, Nikolay Aksenov, Alexey Moshkov, Tatyana Goryachaya, Ashley Shemery & Alexey Vereninov
Pages: 45-52
Published online: 20 Feb 2020
AbstractforFlow fluorometry quantification of anion channel VRAC subunit LRRC8A at the membrane of living U937 cells | Full Text | References | PDF (2.4 MB) | EPUB
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Brief Report
PAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons
James Osei-Owusu, Junhua Yang, Maria Del Carmen Vitery, Mengnan Tian & Zhaozhu Qiu
Pages: 53-58
Published online: 25 Feb 2020
AbstractforPAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons | Full Text | References | PDF (1.4 MB) | EPUB
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Research Article

Article
TRPV1 inhibits smooth muscle cell phenotype switching in a mouse model of abdominal aortic aneurysm
Shuo Wang & Chenhong Jia
Pages: 59-68
Published online: 21 Feb 2020
AbstractforTRPV1 inhibits smooth muscle cell phenotype switching in a mouse model of abdominal aortic aneurysm | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 1416 Views
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Article
Activating Sirt1 by resveratrol suppresses Nav1.7 expression in DRG through miR-182 and alleviates neuropathic pain in rats
Qianqian Jia, Wenze Dong, Liwei Zhang & Xiaochun Yang
Pages: 69-78
Published online: 22 Feb 2020
AbstractforActivating Sirt1 by resveratrol suppresses Nav1.7 expression in DRG through miR-182 and alleviates neuropathic pain in rats | Full Text | References | PDF (2.9 MB) | EPUB
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Review

Regulation of the cold-sensing TRPM8 channels by phosphoinositides and Gq-coupled receptors
Luyu Liu & Tibor Rohacs
Pages: 79-86
Published online: 26 Feb 2020
AbstractforRegulation of the cold-sensing TRPM8 channels by phosphoinositides and Gq-coupled receptors | Full Text | References | PDF (2.3 MB) | EPUB
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Technical Report

Obtaining transition rates from single-channel data without initial parameter seeding
Michael Voldsgaard Clausen
Pages: 87-97
Published online: 28 Feb 2020
AbstractforObtaining transition rates from single-channel data without initial parameter seeding | Full Text | References | PDF (4.1 MB) | EPUB
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Article Commentary

Article Commentary
T-type channels in neuropathic pain - Villain or victim?
Norbert Weiss
Pages: 98-100
Published online: 13 Mar 2020
First Page PreviewforT-type channels in neuropathic pain - Villain or victim? | Full Text | References | PDF (2.2 MB) | EPUB
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Brief Report

Brief Report
Mutations in calmodulin-binding domains of TRPV4/6 channels confer invasive properties to colon adenocarcinoma cells
Atousa Arbabian, Mircea Iftinca, Christophe Altier, Param Priya Singh, Hervé Isambert & Sylvie Coscoy
Pages: 101-109
Published online: 18 Mar 2020
AbstractforMutations in calmodulin-binding domains of TRPV4/6 channels confer invasive properties to colon adenocarcinoma cells | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Review

The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels
Ye Han, Kyle A. Lyman, Kendall M. Foote & Dane M. Chetkovich
Pages: 110-122
Published online: 19 Mar 2020
AbstractforThe structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels | Full Text | References | PDF (2.1 MB) | EPUB
  • 2253 Views
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The quest to identify the mechanism underlying adrenergic regulation of cardiac Ca2+ channels
Daniel Roybal, Jessica A. Hennessey & Steven O. Marx
Pages: 123-131
Published online: 20 Mar 2020
AbstractforThe quest to identify the mechanism underlying adrenergic regulation of cardiac Ca2+ channels | Full Text | References | PDF (1.5 MB) | EPUB
  • 1827 Views
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Brief Report

Brief Report
Transcriptomic analysis of glycan-processing genes in the dorsal root ganglia of diabetic mice and functional characterization on Cav3.2 channels
Robin N. Stringer, Joanna Lazniewska & Norbert Weiss
Pages: 132-140
Published online: 31 Mar 2020
AbstractforTranscriptomic analysis of glycan-processing genes in the dorsal root ganglia of diabetic mice and functional characterization on Cav3.2 channels | Full Text | References | PDF (3.3 MB) | EPUB
  • 1595 Views
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Review

The role of TRPV1 channels in atherosclerosis
Chenyang Zhang, Lifang Ye, Qinggang Zhang, Fei Wu & Lihong Wang
Pages: 141-150
Published online: 10 Apr 2020
AbstractforThe role of TRPV1 channels in atherosclerosis | Full Text | References | PDF (1.5 MB) | EPUB
  • 2886 Views
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Research Article

Article
The CaMKII phosphorylation site Thr1604 in the CaV1.2 channel is involved in pathological myocardial hypertrophy in rats
Jingyuan Li, Siqi Wang, Jie Zhang, Yan Liu, Xi Zheng, Fan Ding, Xuefei Sun, Meimi Zhao & Liying Hao
Pages: 151-162
Published online: 14 Apr 2020
AbstractforThe CaMKII phosphorylation site Thr1604 in the CaV1.2 channel is involved in pathological myocardial hypertrophy in rats | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Article
The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency
Tina Jenewein, Scott A. Kanner, Daniel Bauer, Brigitte Hertel, Henry M. Colecraft, Anna Moroni, Gerhard Thiel & Silke Kauferstein
Pages: 163-174
Published online: 17 Apr 2020
AbstractforThe mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1512 Views
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Brief Report

Brief Report
A de novo CACNA1D missense mutation in a patient with congenital hyperinsulinism, primary hyperaldosteronism and hypotonia
María Carmen De Mingo Alemany, Luis Mifsud Grau, Francisca Moreno Macián, Belén Ferrer Lorente & Sara León Cariñena
Pages: 175-180
Published online: 04 May 2020
AbstractforA de novo CACNA1D missense mutation in a patient with congenital hyperinsulinism, primary hyperaldosteronism and hypotonia | Full Text | References | PDF (1.6 MB) | EPUB
  • 2093 Views
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Research Paper

Article
The effect of MD1 on potassium and L-type calcium current of cardiomyocytes from high-fat diet mice
Wei Shuai, Bin Kong, Hui Fu, Xiaobo Jiang & He Huang
Pages: 181-189
Published online: 03 Jun 2020
AbstractforThe effect of MD1 on potassium and L-type calcium current of cardiomyocytes from high-fat diet mice | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Brief report

Brief Report
The Slo3/Lrrc52 complex is sensitive to phosphoinositides
Takafumi Kawai & Yasushi Okamura
Pages: 190-192
Published online: 21 Jun 2020
AbstractforThe Slo3/Lrrc52 complex is sensitive to phosphoinositides | Full Text | References | PDF (936.8 KB) | EPUB
  • 989 Views
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Commentary

Article Commentary
Bibliometric analysis of calcium channel research (2010–2019)
Jingjing Shi, Huan Wang, Shuqing Shi, Guozhen Yuan, QiuLei Jia, Shuai Shi, Xuesong Zhang & Yuanhui Hu
Pages: 193-202
Published online: 13 Jul 2020
AbstractforBibliometric analysis of calcium channel research (2010–2019) | Full Text | References | PDF (5.1 MB) | EPUB
  • 3283 Views
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Article Commentary
A bibliometric analysis and review of recent researches on TRPM7
Shiqi Zhang, Dongyi Zhao, Wanying Jia, Yuting Wang, Hongyue Liang, Lei Liu, Wuyang Wang, Zhiyi Yu & Feng Guo
Pages: 203-215
Published online: 09 Jul 2020
AbstractforA bibliometric analysis and review of recent researches on TRPM7 | Full Text | References | PDF (3 MB) | EPUB
  • 4013 Views
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Research paper

Article
Sphingosine kinase 2 inhibitor ABC294640 suppresses neuronal excitability and inhibits multiple endogenously and exogenously expressed voltage-gated ion channels in cultured cells
Fei Zhang, Wenqi Hu, Lili Qu & Chunlei Cang
Pages: 216-230
Published online: 13 Jul 2020
AbstractforSphingosine kinase 2 inhibitor ABC294640 suppresses neuronal excitability and inhibits multiple endogenously and exogenously expressed voltage-gated ion channels in cultured cells | Full Text | References | PDF (3.5 MB) | EPUB
  • 1421 Views
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Article
A low voltage activated Ca2+ current found in a subset of human ventricular myocytes
Xin Zhang, Yijia Li, Xiaoying Zhang, Valentino Piacentino III, David M. Harris, Remus Berretta, Kenneth B. Margulies, Steven R. Houser & Xiongwen Chen
Pages: 231-245
Published online: 20 Jul 2020
AbstractforA low voltage activated Ca2+ current found in a subset of human ventricular myocytes | Full Text | References | PDF (10.3 MB) | EPUB
  • 1106 Views
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Article
Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca2+ and Ca2+-dependent regulation of TXNIP
Xiling Zhang, Zhimin Mao, Yanru Huang, Zhen Zhang & Jian Yao
Pages: 246-256
Published online: 04 Aug 2020
AbstractforGap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca2+ and Ca2+-dependent regulation of TXNIP | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
  • 1213 Views
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Review

Polymodal roles of TRPC3 channel in the kidney
Naghmeh Hassanzadeh Khayyat, Viktor N. Tomilin, Oleg Zaika & Oleh Pochynyuk
Pages: 257-267
Published online: 12 Aug 2020
AbstractforPolymodal roles of TRPC3 channel in the kidney | Full Text | References | PDF (3.3 MB) | EPUB
  • 1464 Views
  • 7 CrossRef citations
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Research paper

Article
Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5
Zizun Wang, Sarah H. Vermij, Valentin Sottas, Anna Shestak, Daniela Ross-Kaschitza, Elena V. Zaklyazminskaya, Andy Hudmon, Geoffrey S. Pitt, Jean-Sébastien Rougier & Hugues Abriel
Pages: 268-286
Published online: 20 Aug 2020
AbstractforCalmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5 | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
  • 1944 Views
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Brief report

Brief Report
Loss of Cav1.2 channels impairs hippocampal theta burst stimulation-induced long-term potentiation
Preethy S. Sridharan, Yuan Lu, Richard C Rice, Andrew A. Pieper & Anjali M. Rajadhyaksha
Pages: 287-293
Published online: 15 Aug 2020
AbstractforLoss of Cav1.2 channels impairs hippocampal theta burst stimulation-induced long-term potentiation | Full Text | References | PDF (721.7 KB) | EPUB
  • 1619 Views
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Review

Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains
Sara J. Codding, Ashley A. Johnson & Matthew C. Trudeau
Pages: 294-309
Published online: 12 Sep 2020
AbstractforGating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains | Full Text | References | PDF (6.5 MB) | EPUB
  • 1959 Views
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Research Article

Article
Charged pore-lining residues are required for normal channel kinetics in the eukaryotic mechanosensitive ion channel MSL1
Angela M. Schlegel & Elizabeth S. Haswell
Pages: 310-325
Published online: 29 Sep 2020
AbstractforCharged pore-lining residues are required for normal channel kinetics in the eukaryotic mechanosensitive ion channel MSL1 | Full Text | References | PDF (5.7 MB) | EPUB | Supplemental
  • 1044 Views
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Research Paper

Article
Modulation of Ca2+-induced Ca2+ release by ubiquitin protein ligase E3 component n-recognin UBR3 and 6 in cardiac myocytes
Xiu-E Ma, Bei Liu & Chun-Xia Zhao
Pages: 326-335
Published online: 29 Sep 2020
AbstractforModulation of Ca2+-induced Ca2+ release by ubiquitin protein ligase E3 component n-recognin UBR3 and 6 in cardiac myocytes | Full Text | References | PDF (2.4 MB) | EPUB
  • 1053 Views
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Article
Analysis of Arabidopsis TPK2 and KCO3 reveals structural properties required for K+ channel function
Chihiro Uehara, Kota Takeda, Tatsuki Ibuki, Tadaomi Furuta, Naomi Hoshi, Ellen Tanudjaja & Nobuyuki Uozumi
Pages: 336-346
Published online: 04 Oct 2020
AbstractforAnalysis of Arabidopsis TPK2 and KCO3 reveals structural properties required for K+ channel function | Full Text | References | PDF (6.7 MB) | EPUB | Supplemental
  • 1284 Views
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Article
Experimental induction and mathematical modeling of Ca2+ dynamics in rat round spermatids
Jonathan Saavedra, Juan G. Reyes & Dino G. Salinas
Pages: 347-361
Published online: 07 Oct 2020
AbstractforExperimental induction and mathematical modeling of Ca2+ dynamics in rat round spermatids | Full Text | References | PDF (2.7 MB) | EPUB
  • 962 Views
  • 1 CrossRef citations
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Review

Cav2.3 channel function and Zn2+-induced modulation: potential mechanisms and (patho)physiological relevance
Felix Neumaier, Toni Schneider & Walid Albanna
Pages: 362-379
Published online: 20 Oct 2020
AbstractforCav2.3 channel function and Zn2+-induced modulation: potential mechanisms and (patho)physiological relevance | Full Text | References | PDF (5.9 MB) | EPUB
  • 1192 Views
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Modulation of voltage-gated CaV2.2 Ca2+ channels by newly identified interaction partners
Lubica Lacinova, Robert Theodor Mallmann, Bohumila Jurkovičová-Tarabová & Norbert Klugbauer
Pages: 380-392
Published online: 15 Oct 2020
AbstractforModulation of voltage-gated CaV2.2 Ca2+ channels by newly identified interaction partners | Full Text | References | PDF (3.8 MB) | EPUB
  • 2323 Views
  • 3 CrossRef citations
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Commentary

Article Commentary
Bibliometric analysis of chloride channel research (2004–2019)
Jingjing Shi, Shuqing Shi, Guozhen Yuan, QiuLei Jia, Shuai Shi, Xueping Zhu, Yan Zhou, Ting Chen & Yuanhui Hu
Pages: 393-402
Published online: 24 Oct 2020
First Page PreviewforBibliometric analysis of chloride channel research (2004–2019) | Full Text | References | PDF (3.7 MB) | EPUB
  • 2962 Views
  • 1 CrossRef citations
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Review

Similarities between the effect of SARS-CoV-2 and HCV on the cellular level, and the possible role of ion channels in COVID19 progression: a review of potential targets for diagnosis and treatment
Hani Alothaid, Mohammed S. K. Aldughaim, Karim El Bakkouri, Sufana AlMashhadi & Ahmed A. Al-Qahtani
Pages: 403-412
Published online: 22 Oct 2020
AbstractforSimilarities between the effect of SARS-CoV-2 and HCV on the cellular level, and the possible role of ion channels in COVID19 progression: a review of potential targets for diagnosis and treatment | Full Text | References | PDF (547.3 KB) | EPUB
  • 2369 Views
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The cool things to know about TRPM8!
Mircea Iftinca & Christophe Altier
Pages: 413-420
Published online: 04 Nov 2020
AbstractforThe cool things to know about TRPM8! | Full Text | References | PDF (727.2 KB) | EPUB
  • 6090 Views
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