OncoImmunology, Volume 5, Issue 5 (2016)

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OncoImmunology, Volume 5, Issue 5 (2016)

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Author's View

Opinion
Yet another pattern recognition receptor involved in the chemotherapy-induced anticancer immune response: Formyl peptide receptor-1
Erika Vacchelli, Yuting Ma, Elisa E. Baracco, Laurence Zitvogel & Guido Kroemer
Article: e1118600
Published online: 22 Apr 2016
AbstractforYet another pattern recognition receptor involved in the chemotherapy-induced anticancer immune response: Formyl peptide receptor-1 | Full Text | References | PDF (416.3 KB)
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Opinion
Tetraspanin CD81, a modulator of immune suppression in cancer and metastasis
Felipe Vences-Catalán, Ranjani Rajapaksa, Minu K. Srivastava, Aurelien Marabelle, Chiung-Chi Kuo, Ronald Levy & Shoshana Levy
Article: e1120399
Published online: 19 Apr 2016
AbstractforTetraspanin CD81, a modulator of immune suppression in cancer and metastasis | Full Text | References | PDF (318.6 KB)
  • 1143 Views
  • 9 CrossRef citations
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Opinion
Frameshift mutations, neoantigens and tumor-specific CD8+ T cells in microsatellite unstable colorectal cancers
Pauline Maby, Jérôme Galon & Jean-Baptiste Latouche
Article: e1115943
Published online: 29 Apr 2016
AbstractforFrameshift mutations, neoantigens and tumor-specific CD8+ T cells in microsatellite unstable colorectal cancers | Full Text | References | PDF (366.2 KB)
  • 1854 Views
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Opinion
Harnessing the IL-7/IL-7Rα axis to improve tumor immunotherapy
C. Bryce Johnson, John Wrangle, Shikhar Mehrotra, Zihai Li, Chrystal M. Paulos, David J. Cole, Charles D. Surh & Mark P. Rubinstein
Article: e1122865
Published online: 29 Apr 2016
AbstractforHarnessing the IL-7/IL-7Rα axis to improve tumor immunotherapy | Full Text | References | PDF (301.6 KB)
  • 941 Views
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Opinion
Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy
Maryann E. Mikucki, Joseph J. Skitzki, John G. Frelinger, Kunle Odunsi, Thomas F. Gajewski, Andrew D. Luster & Sharon S. Evans
Article: e1116675
Published online: 29 Apr 2016
AbstractforUnlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy | Full Text | References | PDF (475.1 KB)
  • 1573 Views
  • 9 CrossRef citations
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Opinion
BCR-ABL transcript variations in chronic phase chronic myelogenous leukemia patients on imatinib first-line: Possible role of the autologous immune system
Geoffrey D. Clapp, Thomas Lepoutre, Franck E. Nicolini & Doron Levy
Article: e1122159
Published online: 29 Apr 2016
AbstractforBCR-ABL transcript variations in chronic phase chronic myelogenous leukemia patients on imatinib first-line: Possible role of the autologous immune system | Full Text | References | PDF (351.3 KB)
  • 478 Views
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Opinion
Unraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors
Reiner Strick, Pamela L. Strissel, Stephen B. Baylin & Katherine B. Chiappinelli
Article: e1122160
Published online: 29 Apr 2016
AbstractforUnraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors | Full Text | References | PDF (330.3 KB)
  • 1821 Views
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Opinion
Tumor evasion of humoral immunity mediated by proteolytic impairment of antibody triggered immune effector function
Ningyan Zhang, Robert E. Jordan & Zhiqiang An
Article: e1122861
Published online: 29 Apr 2016
AbstractforTumor evasion of humoral immunity mediated by proteolytic impairment of antibody triggered immune effector function | Full Text | References | PDF (361.3 KB)
  • 687 Views
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Opinion
GITR drives TH9-mediated antitumor immunity
Il-Kyu Kim, Yeonseok Chung & Chang-Yuil Kang
Article: e1122862
Published online: 29 Apr 2016
AbstractforGITR drives TH9-mediated antitumor immunity | Full Text | References | PDF (324.6 KB)
  • 839 Views
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Opinion
Notching tumor: Signaling through Notch receptors improves antitumor T cell immunity
Roman Uzhachenko & Anil Shanker
Article: e1122864
Published online: 29 Apr 2016
AbstractforNotching tumor: Signaling through Notch receptors improves antitumor T cell immunity | Full Text | References | PDF (283.3 KB)
  • 964 Views
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Opinion
Linking cancer-induced Nlrp3 inflammasome activation to efficient NK cell-mediated immunosurveillance
Maryse Dagenais & Maya Saleh
Article: e1129484
Published online: 04 May 2016
AbstractforLinking cancer-induced Nlrp3 inflammasome activation to efficient NK cell-mediated immunosurveillance | Full Text | References | PDF (334.5 KB)
  • 1374 Views
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Opinion
Size matters: Survival benefit conferred by intratumoral T cells is dependent on surgical outcome, treatment sequence and T cell differentiation
M. C. A. Wouters, F. L. Komdeur, M. de Bruyn & H. W. Nijman
Article: e1122863
Published online: 04 May 2016
AbstractforSize matters: Survival benefit conferred by intratumoral T cells is dependent on surgical outcome, treatment sequence and T cell differentiation | Full Text | References | PDF (373.6 KB)
  • 511 Views
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Opinion
Melanoma driver mutations and immune therapy
Douglas B. Johnson, Christine M. Lovly, Ryan J. Sullivan, Richard D. Carvajal & Jeffrey A. Sosman
Article: e1051299
Published online: 04 May 2016
AbstractforMelanoma driver mutations and immune therapy | Full Text | References | PDF (55.2 KB)
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Opinion
Reducing prostaglandin E2 production to raise cancer immunogenicity
Santiago Zelenay & Caetano Reis e Sousa
Article: e1123370
Published online: 11 May 2016
AbstractforReducing prostaglandin E2 production to raise cancer immunogenicity | Full Text | References | PDF (390.9 KB)
  • 1955 Views
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Open Access
Opinion
Motolimod effectively drives immune activation in advanced cancer patients
Gregory N. Dietsch
Article: e1126037
Published online: 11 May 2016
AbstractforMotolimod effectively drives immune activation in advanced cancer patients | Full Text | References | PDF (396.5 KB)
  • 905 Views
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Opinion
Ovarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy
Emese Zsiros, Denarda Dangaj, Carl H. June, Lana E. Kandalaft & George Coukos
Article: e1062210
Published online: 31 May 2016
AbstractforOvarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy | Full Text | References | PDF (389.9 KB)
  • 1050 Views
  • 4 CrossRef citations
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Opinion
CD73-adenosine reduces immune responses and survival in ovarian cancer patients
Pierre-Olivier Gaudreau, Bertrand Allard, Martin Turcotte & John Stagg
Article: e1127496
Published online: 31 May 2016
AbstractforCD73-adenosine reduces immune responses and survival in ovarian cancer patients | Full Text | References | PDF (363.3 KB)
  • 1519 Views
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Brief Report

Brief Report
Tipping a favorable CNS intratumoral immune response using immune stimulation combined with inhibition of tumor-mediated immune suppression
Ling-Yuan Kong, Jun Wei, Gregory N. Fuller, Brett Schrand, Konrad Gabrusiewicz, Shouhao Zhou, Ganesh Rao, George Calin, Eli Gilboa & Amy B. Heimberger
Article: e1117739
Published online: 19 Apr 2016
AbstractforTipping a favorable CNS intratumoral immune response using immune stimulation combined with inhibition of tumor-mediated immune suppression | Full Text | References | PDF (894.8 KB)
  • 822 Views
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Brief Report
TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo
Xiuhong Piao, Tatsuhiko Ozawa, Hiroshi Hamana, Kiyomi Shitaoka, Aishun Jin, Hiroyuki Kishi & Atsushi Muraguchi
Article: e1131380
Published online: 04 May 2016
AbstractforTRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo | Full Text | References | PDF (907.3 KB) | Supplemental
  • 1083 Views
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Editorial

Editorial
STAT3 inhibition for cancer therapy: Cell-autonomous effects only?
Guido Kroemer, Lorenzo Galluzzi & Laurence Zitvogel
Article: e1126063
Published online: 11 May 2016
AbstractforSTAT3 inhibition for cancer therapy: Cell-autonomous effects only? | Full Text | References | PDF (223.4 KB)
  • 1761 Views
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Original Research

Article
The multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma
Sara Pessina, Gabriele Cantini, Dimos Kapetis, Emanuela Cazzato, Natalia Di Ianni, Gaetano Finocchiaro & Serena Pellegatta
Article: e1108513
Published online: 19 Apr 2016
AbstractforThe multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1777 Views
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Article
HLA ligandomics identifies histone deacetylase 1 as target for ovarian cancer immunotherapy
Janet Kerstin Peper, Hans-Christian Bösmüller, Heiko Schuster, Brigitte Gückel, Helen Hörzer, Kevin Roehle, Richard Schäfer, Philipp Wagner, Hans-Georg Rammensee, Stefan Stevanović, Falko Fend & Annette Staebler
Article: e1065369
Published online: 19 Apr 2016
AbstractforHLA ligandomics identifies histone deacetylase 1 as target for ovarian cancer immunotherapy | Full Text | References | PDF (1,000.4 KB) | Supplemental
  • 1712 Views
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Article
Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS
Ornella Franzese, Belinda Palermo, Cosmo Di Donna, Isabella Sperduti, Virginia Ferraresi, Helena Stabile, Angela Gismondi, Angela Santoni & Paola Nisticò
Article: e1114203
Published online: 19 Apr 2016
AbstractforPolyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1429 Views
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Article
Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy
Susanne M. Rittig, Maik Haentschel, Katrin J. Weimer, Annkristin Heine, Martin R. Müller, Wolfram Brugger, Marius S. Horger, Olga Maksimovic, Arnulf Stenzl, Ingmar Hoerr, Hans-Georg Rammensee, Tobias A. Holderried, Lothar Kanz, Steve Pascolo & Peter Brossart
Article: e1108511
Published online: 29 Apr 2016
AbstractforLong-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy | Full Text | References | PDF (656.8 KB) | Supplemental
  • 2515 Views
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Article
Cell-to-cell distances between tumor-infiltrating inflammatory cells have the potential to distinguish functionally active from suppressed inflammatory cells
S. Nagl, M. Haas, G. Lahmer, M. Büttner-Herold, G. G. Grabenbauer, R. Fietkau & L. V. Distel
Article: e1127494
Published online: 29 Apr 2016
AbstractforCell-to-cell distances between tumor-infiltrating inflammatory cells have the potential to distinguish functionally active from suppressed inflammatory cells | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1167 Views
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Article
Nucleic acid-sensing toll-like receptors 3, 7 and 8 in esophageal epithelium, barrett’s esophagus, dysplasia and adenocarcinoma
Olli Helminen, Heikki Huhta, Petri P. Lehenkari, Juha Saarnio, Tuomo J. Karttunen & Joonas H. Kauppila
Article: e1127495
Published online: 29 Apr 2016
AbstractforNucleic acid-sensing toll-like receptors 3, 7 and 8 in esophageal epithelium, barrett’s esophagus, dysplasia and adenocarcinoma | Full Text | References | PDF (5.3 MB)
  • 652 Views
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Article
TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models
Myriam Lamrani, Nejia Sassi, Catherine Paul, Nadhir Yousfi, Jean-Luc Boucher, Nolwenn Gauthier, Jérôme Labbé, Cédric Seignez, Cindy Racoeur, Anne Athias, Romain Guerreiro, Catherine Vergely, Luc Rochette, Ali Bettaieb & Jean-François Jeannin
Article: e1123369
Published online: 29 Apr 2016
AbstractforTLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models | Full Text | References | PDF (800.1 KB) | Supplemental
  • 996 Views
  • 18 CrossRef citations
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Article
Anti-α-enolase antibody limits the invasion of myeloid-derived suppressor cells and attenuates their restraining effector T cell response
Paola Cappello, Elisabetta Tonoli, Roberta Curto, Daniele Giordano, Mirella Giovarelli & Francesco Novelli
Article: e1112940
Published online: 29 Apr 2016
AbstractforAnti-α-enolase antibody limits the invasion of myeloid-derived suppressor cells and attenuates their restraining effector T cell response | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1060 Views
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Article
Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2
Emna Dabbeche-Bouricha, Luiza M. Araujo, Masashi Kato, Armelle Prévost-Blondel & Henri-Jean Garchon
Article: e1100793
Published online: 04 May 2016
AbstractforRapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2 | Full Text | References | PDF (1 MB)
  • 586 Views
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Article
Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis
Lucia Cottone, Annalisa Capobianco, Chiara Gualteroni, Antonella Monno, Isabella Raccagni, Silvia Valtorta, Tamara Canu, Tiziano Di Tomaso, Angelo Lombardo, Antonio Esposito, Rosa Maria Moresco, Alessandro Del Maschio, Luigi Naldini, Patrizia Rovere-Querini, Marco E. Bianchi & Angelo A. Manfredi
Article: e1122860
Published online: 05 May 2016
AbstractforLeukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis | Full Text | References | PDF (2.1 MB) | Supplemental
  • 1235 Views
  • 18 CrossRef citations
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Article
Identification of CD245 as myosin 18A, a receptor for surfactant A: A novel pathway for activating human NK lymphocytes
A. De Masson, J. Giustiniani, A. Marie-Cardine, J. D. Bouaziz, N. Dulphy, D. Gossot, P. Validire, A. Tazi, C. Garbar, M. Bagot, Y. Merrouche & A. Bensussan
Article: e1127493
Published online: 04 May 2016
AbstractforIdentification of CD245 as myosin 18A, a receptor for surfactant A: A novel pathway for activating human NK lymphocytes | Full Text | References | PDF (928.4 KB)
  • 997 Views
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Article
High-risk oncogenic HPV genotype infection associates with increased immune activation and T cell exhaustion in ART-suppressed HIV-1-infected women
Emmanouil Papasavvas, Lea F. Surrey, Deborah K. Glencross, Livio Azzoni, Jocelin Joseph, Tanvier Omar, Michael D. Feldman, Anna-Lise Williamson, Maureen Siminya, Avril Swarts, Xiangfan Yin, Qin Liu, Cynthia Firnhaber & Luis J. Montaner
Article: e1128612
Published online: 02 May 2016
AbstractforHigh-risk oncogenic HPV genotype infection associates with increased immune activation and T cell exhaustion in ART-suppressed HIV-1-infected women | Full Text | References | PDF (914.5 KB) | Supplemental
  • 1330 Views
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Article
Targeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma
Lin-Lin Bu, Guang-Tao Yu, Wei-Wei Deng, Liang Mao, Jian-Feng Liu, Si-Rui Ma, Teng-Fei Fan, Bradford Hall, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun
Article: e1130206
Published online: 04 May 2016
AbstractforTargeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma | Full Text | References | PDF (1.9 MB) | Supplemental
  • 1513 Views
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Article
Priming of neutrophils toward NETosis promotes tumor growth
Mélanie Demers, Siu Ling Wong, Kimberly Martinod, Maureen Gallant, Jessica E. Cabral, Yanming Wang & Denisa D. Wagner
Article: e1134073
Published online: 04 May 2016
AbstractforPriming of neutrophils toward NETosis promotes tumor growth | Full Text | References | PDF (1 MB)
  • 3590 Views
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Article
Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis
Monika Dadrich, Nils H. Nicolay, Paul Flechsig, Sebastian Bickelhaupt, Line Hoeltgen, Falk Roeder, Kai Hauser, Alexandra Tietz, Jürgen Jenne, Ramon Lopez, Manuel Roehrich, Ute Wirkner, Michael Lahn & Peter E. Huber
Article: e1123366
Published online: 11 May 2016
AbstractforCombined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis | Full Text | References | PDF (1.5 MB) | Supplemental
  • 3119 Views
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Article
ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing
Maria Raffaella Zocchi, Caterina Camodeca, Elisa Nuti, Armando Rossello, Roberta Venè, Francesca Tosetti, Irene Dapino, Delfina Costa, Alessandra Musso & Alessandro Poggi
Article: e1123367
Published online: 11 May 2016
AbstractforADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing | Full Text | References | PDF (931.5 KB) | Supplemental
  • 1992 Views
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Article
Cripto-1 vaccination elicits protective immunity against metastatic melanoma
M. A. Ligtenberg, K. Witt, F. Galvez-Cancino, A. Sette, A. Lundqvist, A. Lladser & R. Kiessling
Article: e1128613
Published online: 11 May 2016
AbstractforCripto-1 vaccination elicits protective immunity against metastatic melanoma | Full Text | References | PDF (696 KB) | Supplemental
  • 2065 Views
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Article
PD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations
Andreas H. Scheel, Sascha Ansén, Anne M. Schultheis, Matthias Scheffler, Rieke N. Fischer, Sebastian Michels, Martin Hellmich, Julie George, Thomas Zander, Michael Brockmann, Erich Stoelben, Harry Groen, Wim Timens, Sven Perner, Michael von Bergwelt-Baildon, Reinhard Büttner & Jürgen Wolf
Article: e1131379
Published online: 11 May 2016
AbstractforPD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations | Full Text | References | PDF (1 MB) | Supplemental
  • 4908 Views
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Article
Syngeneic Syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting
Mikko Siurala, Markus Vähä-Koskela, Riikka Havunen, Siri Tähtinen, Simona Bramante, Suvi Parviainen, J. Michael Mathis, Anna Kanerva & Akseli Hemminki
Article: e1136046
Published online: 11 May 2016
AbstractforSyngeneic Syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting | Full Text | References | PDF (882.4 KB) | Supplemental
  • 1610 Views
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Article
Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4+ Th1 responses against telomerase in cancer patients
Caroline Laheurte, Jeanne Galaine, Laurent Beziaud, Magalie Dosset, Jerome Kerzerho, Claire Jacquemard, Béatrice Gaugler, Christophe Ferrand, Anne Dormoy, François Aubin, Pascale Jacoulet, Virginie Westeel, Christophe Borg, Eric Tartour, Yann Godet, Bernard Maillère & Olivier Adotévi
Article: e1137416
Published online: 11 May 2016
AbstractforImmunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4+ Th1 responses against telomerase in cancer patients | Full Text | References | PDF (991.8 KB) | Supplemental
  • 1154 Views
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Article
Thymic hyperplasia after chemotherapy in adults with mature B cell lymphoma and its influence on thymic output and CD4+ T cells repopulation
Dao-Ping Sun, Hui Jin, Chong-Yang Ding, Jin-Hua Liang, Li Wang, Lei Fan, Yu-Jie Wu, Wei Xu & Jian-Yong Li
Article: e1137417
Published online: 11 May 2016
AbstractforThymic hyperplasia after chemotherapy in adults with mature B cell lymphoma and its influence on thymic output and CD4+ T cells repopulation | Full Text | References | PDF (474.7 KB)
  • 1246 Views
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Article
Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma
Hans A. Schlößer, Uta Drebber, Michael Kloth, Martin Thelen, Sacha I. Rothschild, Simon Haase, Maria Garcia-Marquez, Kerstin Wennhold, Felix Berlth, Alexander Urbanski, Hakan Alakus, Astrid Schauss, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Ute Warnecke-Ebertz, Dirk L. Stippel, Alfred Zippelius, Reinhard Büttner, Michael Hallek, Arnulf H. Hölscher, Thomas Zander, Stefan P. Mönig & Michael von Bergwelt-Baildon
Article: e1100789
Published online: 31 May 2016
AbstractforImmune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1611 Views
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Article
Phase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients
Yu Sawada, Toshiaki Yoshikawa, Kazuya Ofuji, Mayuko Yoshimura, Nobuhiro Tsuchiya, Mari Takahashi, Daisuke Nobuoka, Naoto Gotohda, Shinichiro Takahashi, Yuichiro Kato, Masaru Konishi, Taira Kinoshita, Masafumi Ikeda, Kohei Nakachi, Naoya Yamazaki, Shoichi Mizuno, Tadatoshi Takayama, Kenji Yamao, Katsuhiko Uesaka, Junji Furuse, Itaru Endo & Tetsuya Nakatsura
Article: e1129483
Published online: 31 May 2016
AbstractforPhase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients | Full Text | References | PDF (807.4 KB) | Supplemental
  • 3534 Views
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Article
Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma
Gabriele Büchel, Johannes H. Schulte, Luke Harrison, Katharina Batzke, Ulrich Schüller, Wiebke Hansen & Alexander Schramm
Article: e1131378
Published online: 31 May 2016
AbstractforImmune response modulation by Galectin-1 in a transgenic model of neuroblastoma | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1160 Views
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Article
Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
Nadia Mensali, Fan Ying, Vincent Oei Yi Sheng, Weiwen Yang, Even Walseng, Shraddha Kumari, Lars-Egil Fallang, Arne Kolstad, Wolfgang Uckert, Karl Johan Malmberg, Sébastien Wälchli & Johanna Olweus
Article: e1138199
Published online: 12 May 2016
AbstractforTargeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1807 Views
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Article
Serum anti-MDM2 and anti-c-Myc autoantibodies as biomarkers in the early detection of lung cancer
Pei Li, Jian-Xiang Shi, Li-Ping Dai, Yu-Rong Chai, Hong-Fei Zhang, Mutombo Kankonde, Peggy Kankonde, Bao-Fa Yu & Jian-Ying Zhang
Article: e1138200
Published online: 22 Apr 2016
AbstractforSerum anti-MDM2 and anti-c-Myc autoantibodies as biomarkers in the early detection of lung cancer | Full Text | References | PDF (933.8 KB)
  • 1082 Views
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Article
Rituximab-based treatments followed by adoptive cellular immunotherapy for biopsy-proven EBV-associated post-transplant lymphoproliferative disease in recipients of allogeneic hematopoietic stem cell transplantation
Xinmiao Jiang, Lanping Xu, Yu Zhang, Fen Huang, Daihong Liu, Jin Sun, Chaoyang Song, Xinquan Liang, Zhiping Fan, Hongsheng Zhou, Min Dai, Can Liu, Qianli Jiang, Na Xu, Li Xuan, Meiqing Wu, Xiaojun Huang & Qifa Liu
Article: e1139274
Published online: 10 Mar 2016
AbstractforRituximab-based treatments followed by adoptive cellular immunotherapy for biopsy-proven EBV-associated post-transplant lymphoproliferative disease in recipients of allogeneic hematopoietic stem cell transplantation | Full Text | References | PDF (740.3 KB)
  • 1294 Views
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Article
Lenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro
Isabelle Krämer, Melanie Engelhardt, Sabrina Fichtner, Brigitte Neuber, Sergej Medenhoff, Uta Bertsch, Jens Hillengass, Marc-Steffen Raab, Dirk Hose, Anthony D. Ho, Hartmut Goldschmidt & Michael Hundemer
Article: e1139662
Published online: 31 May 2016
AbstractforLenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro | Full Text | References | PDF (741.2 KB) | Supplemental
  • 1397 Views
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Article
The clinical impact of ICOS signal in colorectal cancer patients
Yan Zhang, Yang Luo, Shao-Lan Qin, Yi-Fei Mu, Yang Qi, Min-Hao Yu & Ming Zhong
Article: e1141857
Published online: 10 Mar 2016
AbstractforThe clinical impact of ICOS signal in colorectal cancer patients | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2657 Views
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Article
Combating rituximab resistance by inducing ceramide/lysosome-involved cell death through initiation of CD20-TNFR1 co-localization
Fan Zhang, Junlan Yang, Huafei Li, Moyan Liu, Jie Zhang, Lichao Zhao, Lingxiong Wang, RuiXia LingHu, Fan Feng, Xudong Gao, Biqin Dong, Xiaohan Liu, Jian Zi, Weijing Zhang, Yi Hu, Jingkun Pan, Lei Tian, Yazuo Hu, Zhitao Han, Honghong Zhang, Xiaoning Wang & Lei Zhao
Article: e1143995
Published online: 31 May 2016
AbstractforCombating rituximab resistance by inducing ceramide/lysosome-involved cell death through initiation of CD20-TNFR1 co-localization | Full Text | References | PDF (1.7 MB) | Supplemental
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Article
19F-MRI for monitoring human NK cells in vivo
Myriam N. Bouchlaka, Kai D. Ludwig, Jeremy W. Gordon, Matthew P. Kutz, Bryan P. Bednarz, Sean B. Fain & Christian M. Capitini
Article: e1143996
Published online: 31 May 2016
Abstractfor19F-MRI for monitoring human NK cells in vivo | Full Text | References | PDF (1,014.1 KB)
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Article
Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma
Ioannis Karydis, Pui Ying Chan, Matthew Wheater, Edurne Arriola, Peter W. Szlosarek & Christian H. Ottensmeier
Article: e1143997
Published online: 31 May 2016
AbstractforClinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma | Full Text | References | PDF (770.5 KB)
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Article
The ratio of CD8 to Treg tumor-infiltrating lymphocytes is associated with response to cisplatin-based neoadjuvant chemotherapy in patients with muscle invasive urothelial carcinoma of the bladder
Alexander S. Baras, Charles Drake, Jen-Jane Liu, Nilay Gandhi, Max Kates, Mohamed O. Hoque, Alan Meeker, Noah Hahn, Janis M. Taube, Mark P. Schoenberg, George Netto & Trinity J. Bivalacqua
Article: e1134412
Published online: 31 May 2016
AbstractforThe ratio of CD8 to Treg tumor-infiltrating lymphocytes is associated with response to cisplatin-based neoadjuvant chemotherapy in patients with muscle invasive urothelial carcinoma of the bladder | Full Text | References | PDF (566.6 KB) | Supplemental
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Review

Review
Producer T cells: Using genetically engineered T cells as vehicles to generate and deliver therapeutics to tumors
Alexander K. Tsai & Eduardo Davila
Article: e1122158
Published online: 19 Apr 2016
AbstractforProducer T cells: Using genetically engineered T cells as vehicles to generate and deliver therapeutics to tumors | Full Text | References | PDF (549.6 KB)
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Review
Cytokine patterns in cancer patients: A review of the correlation between interleukin 6 and prognosis
Bodo E. Lippitz & Robert A. Harris
Article: e1093722
Published online: 11 May 2016
AbstractforCytokine patterns in cancer patients: A review of the correlation between interleukin 6 and prognosis | Full Text | References | PDF (556.1 KB)
  • 4738 Views
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Review
Regulatory B lymphocyte functions should be considered in chronic lymphocytic leukemia
Audrey Mohr, Yves Renaudineau, Cristina Bagacean, Jacques-Olivier Pers, Christophe Jamin & Anne Bordron
Article: e1132977
Published online: 11 May 2016
AbstractforRegulatory B lymphocyte functions should be considered in chronic lymphocytic leukemia | Full Text | References | PDF (495 KB)
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Editorial Retraction

Retraction
Editorial retraction
Article: e1173506
Published online: 29 Apr 2016
CitationforEditorial retraction | Full Text | PDF (82.7 KB)
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