Virulence, Volume 8, Issue 2 (2017)

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Virulence, Volume 8, Issue 2 (2017)

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New Antifungal Compounds

Editorial

Article Commentary
Virulence factors associated with Aggregatibacter actinomycetemcomitans and their role in promoting periodontal diseases
Bruna Benso
Pages: 111-114
Published online: 01 Nov 2016
First Page PreviewforVirulence factors associated with Aggregatibacter actinomycetemcomitans and their role in promoting periodontal diseases | Full Text | References | PDF (435.6 KB)
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Research Paper

Article
A novel intrinsically disordered outer membrane lipoprotein of Aggregatibacter actinomycetemcomitans binds various cytokines and plays a role in biofilm response to interleukin-1β and interleukin-8
Tuuli Ahlstrand, Heidi Tuominen, Arzu Beklen, Annamari Torittu, Jan Oscarsson, Raija Sormunen, Marja T. Pöllänen, Perttu Permi & Riikka Ihalin
Pages: 115-134
Published online: 26 Aug 2016
AbstractforA novel intrinsically disordered outer membrane lipoprotein of Aggregatibacter actinomycetemcomitans binds various cytokines and plays a role in biofilm response to interleukin-1β and interleukin-8 | Full Text | References | PDF (1.2 MB)
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Editorial

Editorial
The unmet clinical need of novel antifungal drugs
Damian J. Krysan
Pages: 135-137
Published online: 02 Mar 2017
First Page PreviewforThe unmet clinical need of novel antifungal drugs | Full Text | References | PDF (247.2 KB)
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Brief Report

Brief Report
Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi
Nathan P. Wiederhold, Thomas F. Patterson, Anand Srinivasan, Ashok K. Chaturvedi, Annette W. Fothergill, Floyd L. Wormley, Anand K. Ramasubramanian & José L. Lopez-Ribot Pharm.D./Ph.D
Pages: 138-142
Published online: 24 Jun 2016
AbstractforRepurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi | Full Text | References | PDF (325 KB)
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Review

Article Commentary
Trehalose pathway as an antifungal target
John R. Perfect MD, James B. Duke Professor of Medicine, Jennifer L. Tenor, Yi Miao & Richard G. Brennan
Pages: 143-149
Published online: 17 Jun 2016
AbstractforTrehalose pathway as an antifungal target | Full Text | References | PDF (423.2 KB)
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Review Article
Targeting Candida albicans filamentation for antifungal drug development
Taissa Vila, Jesus A. Romo, Christopher G. Pierce, Stanton F. McHardy, Stephen P. Saville & José L. Lopez-Ribot Pharm.D./Ph.D
Pages: 150-158
Published online: 24 Jun 2016
AbstractforTargeting Candida albicans filamentation for antifungal drug development | Full Text | References | PDF (524.5 KB)
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Review Article
Exploiting mitochondria as targets for the development of new antifungals
Dongmei Li & Richard Calderone
Pages: 159-168
Published online: 09 Jun 2016
AbstractforExploiting mitochondria as targets for the development of new antifungals | Full Text | References | PDF (798.3 KB)
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Review Article
Combinatorial strategies for combating invasive fungal infections
Michaela Spitzer, Nicole Robbins & Gerard D. Wright
Pages: 169-185
Published online: 24 Jun 2016
AbstractforCombinatorial strategies for combating invasive fungal infections | Full Text | References | PDF (978.1 KB)
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Review Article
Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach
Praveen R. Juvvadi, Soo Chan Lee, Joseph Heitman & William J. Steinbach
Pages: 186-197
Published online: 07 Jul 2016
AbstractforCalcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach | Full Text | References | PDF (537.1 KB)
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Review Article
Antifungal adjuvants: Preserving and extending the antifungal arsenal
Arielle Butts, Glen E. Palmer & P. David Rogers
Pages: 198-210
Published online: 19 Aug 2016
AbstractforAntifungal adjuvants: Preserving and extending the antifungal arsenal | Full Text | References | PDF (505.2 KB)
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Review
Antifungal therapeutics for dimorphic fungal pathogens
Kristie D. Goughenour & Chad A. Rappleye
Pages: 211-221
Published online: 01 Nov 2016
AbstractforAntifungal therapeutics for dimorphic fungal pathogens | Full Text | References | PDF (463.3 KB)
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Review Article
New facets of antifungal therapy
Ya-Lin Chang, Shang-Jie Yu, Joseph Heitman, Melanie Wellington & Ying-Lien Chen
Pages: 222-236
Published online: 02 Dec 2016
AbstractforNew facets of antifungal therapy | Full Text | References | PDF (510.6 KB)
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Letter to the Editor

Letter
Trehalose as antifungal target: The picture is still incomplete
Juan-Carlos Argüelles
Pages: 237-238
Published online: 15 Sep 2016
CitationforTrehalose as antifungal target: The picture is still incomplete | Full Text | References | PDF (243.7 KB)
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Article Commentary
Reply to Argüelles
John R. Perfect MD
Page: 239
Published online: 02 Sep 2016
CitationforReply to Argüelles | Full Text | References | PDF (162 KB)
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