Emerging Microbes & Infections, Volume 11, Issue 1 (2022)

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Emerging Microbes & Infections, Volume 11, Issue 1 (2022)

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Coronaviruses

Article
The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron
Li Zhang, Qianqian Li, Ziteng Liang, Tao Li, Shuo Liu, Qianqian Cui, Jianhui Nie, Qian Wu, Xiaowang Qu, Weijin Huang & Youchun Wang
Pages: 1-5
Published online: 21 Dec 2021
AbstractforThe significant immune escape of pseudotyped SARS-CoV-2 variant Omicron | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Research Article

Article
Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany
Christina Frank, Jonathan Wickel, Dirk Brämer, Jakob Matschke, Richard Ibe, Caroline Gazivoda, Albrecht Günther, Christian Hartmann, Kordt Rehn, Daniel Cadar, Thomas E. Mayer, Kirsten Pörtner, Hendrik Wilking, Jonas Schmidt-Chanasit & Dennis Tappe
Pages: 6-13
Published online: 21 Dec 2021
AbstractforHuman Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany | Full Text | References | PDF (2.6 MB) | EPUB
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Coronaviruses

Letter
Identification of the SARS-CoV-2 Delta variant C22995A using a high-resolution melting curve RT-FRET-PCR
Subarna Barua, Jianfa Bai, Patrick John Kelly, Gregg Hanzlicek, Lance Noll, Calvin Johnson, Ji-Hang Yin & Chengming Wang
Pages: 14-17
Published online: 21 Dec 2021
AbstractforIdentification of the SARS-CoV-2 Delta variant C22995A using a high-resolution melting curve RT-FRET-PCR | Full Text | References | PDF (997.5 KB) | EPUB | Supplemental
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Open Access
Article
Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination
Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang & Weijin Huang
Pages: 18-29
Published online: 21 Dec 2021
AbstractforReduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Cell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy
Yue Chen, Hongliang Jin, Xiaoran Tang, Li Li, Xiuzhu Geng, Yuanmei Zhu, Huihui Chong & Yuxian He
Pages: 30-49
Published online: 21 Dec 2021
AbstractforCell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy | Full Text | References | PDF (4.5 MB) | EPUB | Supplemental
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Coronaviruses

Article
Outcomes of patients with severe and critical COVID-19 treated with dexamethasone: a prospective cohort study
Bernardo A. Martinez-Guerra, Maria F. Gonzalez-Lara, Carla M. Roman-Montes, Karla M. Tamez-Torres, Francisco E. Dardón-Fierro, Sandra Rajme-Lopez, Carla Medrano-Borromeo, Alejandra Martínez-Valenzuela, Edgar Ortiz-Brizuela, Jose Sifuentes-Osornio & Alfredo Ponce-de-Leon
Pages: 50-59
Published online: 21 Dec 2021
AbstractforOutcomes of patients with severe and critical COVID-19 treated with dexamethasone: a prospective cohort study | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
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Research Article

Article
Different impact of bovine complement regulatory protein 46 (CD46bov) as a cellular receptor for members of the species Pestivirus H and Pestivirus G
Elena Leveringhaus, Gökce Nur Cagatay, Juliane Hardt, Paul Becher & Alexander Postel
Pages: 60-72
Published online: 04 Jan 2022
AbstractforDifferent impact of bovine complement regulatory protein 46 (CD46bov) as a cellular receptor for members of the species Pestivirus H and Pestivirus G | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Open Access

Influenza Infections

Article
Emergence, prevalence, and evolution of H5N8 avian influenza viruses in central China, 2020
Xiang Li, Xinru Lv, Yi Li, Linhong Xie, Peng Peng, Qing An, Tian Fu, Siyuan Qin, Yuan Cui, Chengbo Zhang, Rongxiu Qin, Fengyi Qu, Zhenliang Zhao, Meixi Wang, Qiuzi Xu, Yong Li, Guoxiang Yang, Guang Chen, Jun Zhang, Hesong Zheng, Enda Ma, Ruifang Zhou, Xiangwei Zeng, Yulong Wang, Zhijun Hou, Yajun Wang, Dong Chu, Yanbing Li & Hongliang Chai
Pages: 73-82
Published online: 22 Dec 2021
AbstractforEmergence, prevalence, and evolution of H5N8 avian influenza viruses in central China, 2020 | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Research Article

Article
Association of capsular polysaccharide locus 2 with prognosis of Acinetobacter baumannii bacteraemia
Jia-Ling Yang, Chia-Jui Yang, Yu-Chung Chuang, Wang-Huei Sheng, Yee-Chun Chen & Shan-Chwen Chang
Pages: 83-90
Published online: 21 Dec 2021
AbstractforAssociation of capsular polysaccharide locus 2 with prognosis of Acinetobacter baumannii bacteraemia | Full Text | References | PDF (800.3 KB) | EPUB
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Coronaviruses

Letter
Experimental and field investigations of exposure, replication and transmission of SARS-CoV-2 in pigs in the Netherlands
Reina S. Sikkema, Tijs Tobias, Nadia Oreshkova, Erwin de Bruin, Nisreen Okba, Felicity Chandler, Marcel M. Hulst, Jordi Rodon, Manon Houben, Kees van Maanen, Hans Bultman, Marina Meester, Nora M. Gerhards, Martijn Bouwknegt, Bert Urlings, Bart Haagmans, Jan Kluytmans, Corine H. GeurtsvanKessel, Wim H.M. van der Poel, Marion P.G. Koopmans & Arjan Stegeman
Pages: 91-94
Published online: 21 Dec 2021
AbstractforExperimental and field investigations of exposure, replication and transmission of SARS-CoV-2 in pigs in the Netherlands | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Open Access
Article
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer
Konner Cool, Natasha N. Gaudreault, Igor Morozov, Jessie D. Trujillo, David A. Meekins, Chester McDowell, Mariano Carossino, Dashzeveg Bold, Dana Mitzel, Taeyong Kwon, Velmurugan Balaraman, Daniel W. Madden, Bianca Libanori Artiaga, Roman M. Pogranichniy, Gleyder Roman-Sosa, Jamie Henningson, William C. Wilson, Udeni B. R. Balasuriya, Adolfo García-Sastre & Juergen A. Richt
Pages: 95-112
Published online: 21 Dec 2021
AbstractforInfection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Replicative transposition contributes to the evolution and dissemination of KPC-2-producing plasmid in Enterobacterales
Yu Tang, Gang Li, Pinghua Shen, Ying Zhang & Xiaofei Jiang
Pages: 113-122
Published online: 21 Dec 2021
AbstractforReplicative transposition contributes to the evolution and dissemination of KPC-2-producing plasmid in Enterobacterales | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Research Article

Article
Sequence duplication in 3′ UTR modulates virus replication and virulence of Japanese encephalitis virus
Qiu-Yan Zhang, Si-Qing Liu, Xiao-Dan Li, Jia-Qi Li, Ya-Nan Zhang, Cheng-Lin Deng, Hong-Lei Zhang, Xu-Fang Li, Chun-Xiao Fang, Feng-Xia Yang, Bo Zhang, Yi Xu & Han-Qing Ye
Pages: 123-135
Published online: 21 Dec 2021
AbstractforSequence duplication in 3′ UTR modulates virus replication and virulence of Japanese encephalitis virus | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 4173 Views
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Open Access
Article
Host–pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella
Victor Garcia-Bustos, Javier Pemán, Alba Ruiz-Gaitán, Marta Dafne Cabañero-Navalon, Ana Cabanilles-Boronat, María Fernández-Calduch, Lucía Marcilla-Barreda, Ignacio A. Sigona-Giangreco, Miguel Salavert, María Ángeles Tormo-Mas & Amparo Ruiz-Saurí
Pages: 136-146
Published online: 21 Dec 2021
AbstractforHost–pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella | Full Text | References | PDF (2.7 MB) | EPUB
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Coronaviruses

Article
A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses
Pengfei Wang, Ryan G. Casner, Manoj S. Nair, Jian Yu, Yicheng Guo, Maple Wang, Jasper F.-W. Chan, Gabriele Cerutti, Sho Iketani, Lihong Liu, Zizhang Sheng, Zhiwei Chen, Kwok-Yung Yuen, Peter D. Kwong, Yaoxing Huang, Lawrence Shapiro & David D. Ho
Pages: 147-157
Published online: 28 Dec 2021
AbstractforA monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
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Research Article

Article
Immune reconstruction effectiveness of combination antiretroviral therapy for HIV-1 CRF01_AE cluster 1 and 2 infected individuals
Kang Li, Huanhuan Chen, Jianjun Li, Yi Feng, Guanghua Lan, Shujia Liang, Meiliang Liu, Abdur Rashid, Hui Xing, Zhiyong Shen & Yiming Shao
Pages: 158-167
Published online: 28 Dec 2021
AbstractforImmune reconstruction effectiveness of combination antiretroviral therapy for HIV-1 CRF01_AE cluster 1 and 2 infected individuals | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 3189 Views
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Coronaviruses

Letter
Two novel human coronavirus OC43 genotypes circulating in hospitalized children with pneumonia in China
Zhaoyong Zhang, Wenkuan Liu, Shengnan Zhang, Peilan Wei, Lu Zhang, Dehui Chen, Shuyan Qiu, Xiaobo Li, Jingxian Zhao, Yongxia Shi, Rong Zhou, Yanqun Wang & Jincun Zhao
Pages: 168-171
Published online: 04 Jan 2022
AbstractforTwo novel human coronavirus OC43 genotypes circulating in hospitalized children with pneumonia in China | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 4285 Views
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Open Access
Article
A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain)
Cristina Andrés, Maria Piñana, Blanca Borràs-Bermejo, Alejandra González-Sánchez, Damir García-Cehic, Juliana Esperalba, Ariadna Rando, Ricardo-Gabriel Zules-Oña, Carolina Campos, Maria Gema Codina, Albert Blanco-Grau, Sergi Colomer-Castell, Maria Carmen Martín, Carla Castillo, Karen García-Comuñas, Rodrigo Vásquez-Mercado, Reginaldo Martins-Martins, Narcís Saubi, Magda Campins-Martí, Tomàs Pumarola, Josep Quer & Andrés Antón
Pages: 172-181
Published online: 04 Jan 2022
AbstractforA year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain) | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 3749 Views
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Open Access
Article
A second functional furin site in the SARS-CoV-2 spike protein
Yue Zhang, Li Zhang, Jiajing Wu, Yuanling Yu, Shuo Liu, Tao Li, Qianqian Li, Ruxia Ding, Haixin Wang, Jianhui Nie, Zhimin Cui, Yulin Wang, Weijin Huang & Youchun Wang
Pages: 182-194
Published online: 04 Jan 2022
AbstractforA second functional furin site in the SARS-CoV-2 spike protein | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 6053 Views
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Ebola

Article
Pharmacologically induced endolysosomal cholesterol imbalance through clinically licensed drugs itraconazole and fluoxetine impairs Ebola virus infection in vitro
Susann Kummer, Angelika Lander, Jonas Goretzko, Norman Kirchoff, Ursula Rescher & Sebastian Schloer
Pages: 195-207
Published online: 07 Jan 2022
AbstractforPharmacologically induced endolysosomal cholesterol imbalance through clinically licensed drugs itraconazole and fluoxetine impairs Ebola virus infection in vitro | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 3169 Views
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Coronaviruses

Article Commentary
Omicron: a drug developer’s perspective
Fang “Flora” Fang & Pei-Yong Shi
Pages: 208-211
Published online: 04 Jan 2022
AbstractforOmicron: a drug developer’s perspective | Full Text | References | PDF (459.9 KB) | EPUB
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Open Access
Article
Preclinical immunological evaluation of an intradermal heterologous vaccine against SARS-CoV-2 variants
Shengtao Fan, Kang Xiao, Dandan Li, Heng Zhao, Jingjing Zhang, Li Yu, Penglan Chang, Shuangli Zhu, Xingli Xu, Yun Liao, Tianjiao Ji, Guorun Jiang, Dongmei Yan, Fengyuan Zeng, Suqin Duan, Baicheng Xia, Lichun Wang, Fengmei Yang, Zhanlong He, Yang Song, Pingfang Cui, Xiaolei Li, Yaxing Zhang, Bangyi Zheng, Ying Zhang, Wenbo Xu & Qihan Li
Pages: 212-226
Published online: 07 Jan 2022
AbstractforPreclinical immunological evaluation of an intradermal heterologous vaccine against SARS-CoV-2 variants | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 4399 Views
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Research Article

Article
Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1–4
Tomokazu Tamura, Jiayu Zhang, Vrinda Madan, Abhishek Biswas, Michael P. Schwoerer, Thomas R. Cafiero, Brigitte L. Heller, Wei Wang & Alexander Ploss
Pages: 227-239
Published online: 07 Jan 2022
AbstractforGeneration and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1–4 | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 5686 Views
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Article
COVID-19 prevention measures reduce dengue spread in Yunnan Province, China, but do not reduce established outbreak
Z.Y. Sheng, M. Li, R. Yang, Y.H. Liu, X.X. Yin, J. R. Mao, Heidi E. Brown, J. An, H.N. Zhou & P.G. Wang
Pages: 240-249
Published online: 07 Jan 2022
AbstractforCOVID-19 prevention measures reduce dengue spread in Yunnan Province, China, but do not reduce established outbreak | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 3297 Views
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Coronaviruses

Article
A new testing platform using fingerstick blood for quantitative antibody response evaluation after SARS-CoV-2 vaccination
Jinwei Du, Dayu Zhang, Joseph A. Pathakamuri, Daniel Kuebler, Ying Yang, Yulia Loginova, Eric Chu, Roberta Madej, Jocelyn V. Neves, Brianna Singer, Holly Radke, Naomi Spencer, Elizabeth Rizk, Aiguo Zhang, Chuanyi M. Lu & Michael Y. Sha
Pages: 250-259
Published online: 07 Jan 2022
AbstractforA new testing platform using fingerstick blood for quantitative antibody response evaluation after SARS-CoV-2 vaccination | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3227 Views
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Article
Enhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula
Nigeer Te, Jordi Rodon, Mónica Pérez, Joaquim Segalés, Júlia Vergara-Alert & Albert Bensaid
Pages: 260-274
Published online: 01 Feb 2022
AbstractforEnhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Comment

Comment
Future science prize goes to EMI editorial board members and the science of emerging infections
Shan Lu & Yu-mei Wen
Pages: 275-276
Published online: 16 Jan 2022
CitationforFuture science prize goes to EMI editorial board members and the science of emerging infections | Full Text | References | PDF (354.2 KB) | EPUB
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Coronaviruses

Article
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells
Hanjun Zhao, Lu Lu, Zheng Peng, Lin-Lei Chen, Xinjin Meng, Chuyuan Zhang, Jonathan Daniel Ip, Wan-Mui Chan, Allen Wing-Ho Chu, Kwok-Hung Chan, Dong-Yan Jin, Honglin Chen, Kwok-Yung Yuen & Kelvin Kai-Wang To
Pages: 277-283
Published online: 19 Jan 2022
AbstractforSARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells | Full Text | References | PDF (2.1 MB) | EPUB
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Research Article

Article
Epidemiology of ticks submitted from human hosts in Alberta, Canada (2000–2019)
Jamil N. Kanji, Abraam Isaac, Daniel Gregson, Monika Mierzejewski, Danny Shpeley, Pauline Tomlin, Michael Groeschel, L. Robbin Lindsay, Lisa Lachance & Kinga Kowalewska-Grochowska
Pages: 284-292
Published online: 01 Feb 2022
AbstractforEpidemiology of ticks submitted from human hosts in Alberta, Canada (2000–2019) | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2484 Views
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Antimicrobial Agents

Article
Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides
Wen Zhang, ZhiFei Li, Yufan Sun, Peng Cui, Jianhua Liang, Qinghe Xing, Jing Wu, Yanhui Xu, Wenhong Zhang, Ying Zhang, Lin He & Ning Gao
Pages: 293-305
Published online: 21 Jan 2022
AbstractforCryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 5751 Views
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Coronaviruses

Letter
Genetic analysis of a SARS-CoV-2 Omicron variant from a Chinese traveller returning from overseas
Hongling Jia, Hui Wang, Lan Cao, Zhisheng Lai, Zichun Cheng, Qingpei Chen, Tongzheng Liu, Xiangyi Liu, Yanting Wen, Conghui Xu, Weizhi Lu, Guang Yang, Deqian Zhou, Biao Di, Feng Gao & Zhicong Yang
Pages: 306-309
Published online: 04 Feb 2022
AbstractforGenetic analysis of a SARS-CoV-2 Omicron variant from a Chinese traveller returning from overseas | Full Text | References | PDF (706 KB) | EPUB
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Research Article

Article
The first case of Francisella novicida infection in Taiwan: bacteraemic pneumonia in a haemodialysis adult
Hao-En Jan, Chin-Shiang Tsai, Nan-Yao Lee, Pei-Fang Tsai, Li-Rong Wang, Po-Lin Chen & Wen-Chien Ko
Pages: 310-313
Published online: 21 Jan 2022
AbstractforThe first case of Francisella novicida infection in Taiwan: bacteraemic pneumonia in a haemodialysis adult | Full Text | References | PDF (563.1 KB) | EPUB
  • 1980 Views
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Article
Establishing and applying an adaptive strategy and approach to eliminating malaria: practice and lessons learnt from China from 2011 to 2020
Fang Huang, Xin-Yu Feng, Shui-Sen Zhou, Lin-Hua Tang & Zhi-Gui Xia
Pages: 314-325
Published online: 21 Jan 2022
AbstractforEstablishing and applying an adaptive strategy and approach to eliminating malaria: practice and lessons learnt from China from 2011 to 2020 | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2698 Views
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Article
Genomic epidemiology and characterisation of penicillin-sensitive Staphylococcus aureus isolates from invasive bloodstream infections in China: an increasing prevalence and higher diversity in genetic typing be revealed
Ye Jin, Wangxiao Zhou, Qing Zhan, Yunbo Chen, Qixia Luo, Ping Shen & Yonghong Xiao
Pages: 326-336
Published online: 21 Jan 2022
AbstractforGenomic epidemiology and characterisation of penicillin-sensitive Staphylococcus aureus isolates from invasive bloodstream infections in China: an increasing prevalence and higher diversity in genetic typing be revealed | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 3750 Views
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Coronaviruses

Article
Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost
Jingwen Ai, Haocheng Zhang, Yi Zhang, Ke Lin, Yanliang Zhang, Jing Wu, Yanming Wan, Yanfang Huang, Jieyu Song, Zhangfan Fu, Hongyu Wang, Jingxin Guo, Ning Jiang, Mingxiang Fan, Yang Zhou, Yuanhan Zhao, Qiran Zhang, Qiang Liu, Jing Lv, Peiyao Li, Chao Qiu & Wenhong Zhang
Pages: 337-343
Published online: 24 Jan 2022
AbstractforOmicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 24155 Views
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Antimicrobial Agents

Article
Dissemination and genome analysis of high-level ceftriaxone-resistant penA 60.001 Neisseria gonorrhoeae strains from the Guangdong Gonococcal antibiotics susceptibility Programme (GD-GASP), 2016–2019
Xiaomian Lin, Wentao Chen, Qinghui Xie, Yuqi Yu, Yiwen Liao, Zhanjin Feng, Xiaolin Qin, Xingzhong Wu, Sanmei Tang & Heping Zheng
Pages: 344-350
Published online: 24 Jan 2022
AbstractforDissemination and genome analysis of high-level ceftriaxone-resistant penA 60.001 Neisseria gonorrhoeae strains from the Guangdong Gonococcal antibiotics susceptibility Programme (GD-GASP), 2016–2019 | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 3824 Views
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Coronaviruses

Article
Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein
Shiqi Xu, Yifan Wang, Yanxing Wang, Chao Zhang, Qin Hong, Chenjian Gu, Rong Xu, Tingfeng Wang, Yong Yang, Jinkai Zang, Yu Zhou, Zuyang Li, Qixing Liu, Bingjie Zhou, Lulu Bai, Yuanfei Zhu, Qiang Deng, Haikun Wang, Dimitri Lavillette, Gary Wong, Youhua Xie, Yao Cong & Zhong Huang
Pages: 351-367
Published online: 24 Jan 2022
AbstractforMapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
  • 5351 Views
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Article
Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model
Yanxia Chen, Can Li, Feifei Liu, Zhanhong Ye, Wenchen Song, Andrew C. Y. Lee, Huiping Shuai, Lu Lu, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Hin Chu & Kwok-Yung Yuen
Pages: 368-383
Published online: 24 Jan 2022
AbstractforAge-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model | Full Text | References | PDF (4.2 MB) | EPUB
  • 6999 Views
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Review

Review
WHO informal consultation on regulatory considerations for evaluation of the quality, safety and efficacy of RNA-based prophylactic vaccines for infectious diseases, 20–22 April 2021
Margaret A. Liu, Tiequn Zhou, Rebecca L. Sheets, Heidi Meyer & Ivana Knezevic
Pages: 384-391
Published online: 31 Jan 2022
AbstractforWHO informal consultation on regulatory considerations for evaluation of the quality, safety and efficacy of RNA-based prophylactic vaccines for infectious diseases, 20–22 April 2021 | Full Text | References | PDF (714.9 KB) | EPUB
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Research Article

Article
Pharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4+ T cells
Jing Wen, Xin Li, Qing-Xia Zhao, Xiao-Fan Yang, Meng-Li Wu, Qihong Yan, Junbiao Chang, Haikun Wang, Xia Jin, Xiao Su, Kai Deng, Ling Chen & Jian-Hua Wang
Pages: 392-406
Published online: 01 Feb 2022
AbstractforPharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4+ T cells | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 5241 Views
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Coronaviruses

Letter
Direct neuronal infection of SARS-CoV-2 reveals cellular and molecular pathology of chemosensory impairment of COVID-19 patients
Kwang-Soo Lyoo, Hyeon Myeong Kim, Bina Lee, Young Hyun Che, Seong-Jae Kim, Daesub Song, Woochang Hwang, Sun Lee, Jae-Hoon Park, Woonsung Na, Seung Pil Yun & Yong Jun Kim
Pages: 407-412
Published online: 27 Jan 2022
AbstractforDirect neuronal infection of SARS-CoV-2 reveals cellular and molecular pathology of chemosensory impairment of COVID-19 patients | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 4894 Views
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Article
Sequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tract
Manel Essaidi-Laziosi, Catia Alvarez, Olha Puhach, Pascale Sattonnet-Roche, Giulia Torriani, Caroline Tapparel, Laurent Kaiser & Isabella Eckerle
Pages: 413-424
Published online: 27 Jan 2022
AbstractforSequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tract | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Letter
Resistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma
Yingdan Wang, Yunping Ma, Yan Xu, Jiangyan Liu, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang, Fan Wu & Jinghe Huang
Pages: 425-428
Published online: 28 Jan 2022
First Page PreviewforResistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma | Full Text | References | PDF (743.8 KB) | EPUB
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Research Article

Article
A CRISPR/Cas12a-based DNAzyme visualization system for rapid, non-electrically dependent detection of Bacillus anthracis
Dongshu Wang, Gang Chen, Yufei Lyu, Erling Feng, Li Zhu, Chao Pan, Weicai Zhang, Xiankai Liu & Hengliang Wang
Pages: 429-438
Published online: 01 Feb 2022
AbstractforA CRISPR/Cas12a-based DNAzyme visualization system for rapid, non-electrically dependent detection of Bacillus anthracis | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Coronaviruses

Letter
Safety, mucosal and systemic immunopotency of an aerosolized adenovirus-vectored vaccine against SARS-CoV-2 in rhesus macaques
Fang Xu, Shipo Wu, Linan Yi, Shaodan Peng, Fan Wang, Weixue Si, Lihua Hou & Tao Zhu
Pages: 439-442
Published online: 29 Jan 2022
AbstractforSafety, mucosal and systemic immunopotency of an aerosolized adenovirus-vectored vaccine against SARS-CoV-2 in rhesus macaques | Full Text | References | PDF (739.5 KB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries: a systematic review and meta-analysis
Olaniyi Ayobami, Simon Brinkwirth, Tim Eckmanns & Robby Markwart
Pages: 443-451
Published online: 04 Feb 2022
AbstractforAntibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries: a systematic review and meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Coronaviruses

Article
B cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses
Ke Lin, Yawen Zhou, Jingwen Ai, Yan A. Wang, Senxin Zhang, Chao Qiu, Chaoyang Lian, Bo Gao, Tingting Liu, Hongyu Wang, Haocheng Zhang, Yi Zhang, Zhangfan Fu, Dan Li, Ning Jiang, Jingxin Guo, Jing Wu, Yan O. Wang, Shusen Song, Qiang Li, Yanan Yin, Jia Xia, Yingjie Xu, Leng-Siew Yeap, Xiaoqi Zheng, Ye Gu, Hongyan Liu, Wenhong Zhang & Fei-Long Meng
Pages: 452-464
Published online: 04 Feb 2022
AbstractforB cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Article
A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon
Na Li, Xiao-Ling Chen, Qi Li, Zhe-Rui Zhang, Cheng-Lin Deng, Bo Zhang, Xiao-Dan Li & Han-Qing Ye
Pages: 465-476
Published online: 04 Feb 2022
AbstractforA new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon | Full Text | References | PDF (2.7 MB) | EPUB
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Article
Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies
Xun Wang, Xiaoyu Zhao, Jieyu Song, Jing Wu, Yuqi Zhu, Minghui Li, Yuchen Cui, Yanjia Chen, Lulu Yang, Jun Liu, Huanzhang Zhu, Shibo Jiang & Pengfei Wang
Pages: 477-481
Published online: 04 Feb 2022
AbstractforHomologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies | Full Text | References | PDF (837.5 KB) | EPUB | Supplemental
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Correction

Correction
Correction
Page: 482
Published online: 10 Feb 2022
CitationforCorrection | Full Text | PDF (118.2 KB) | EPUB
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Free Access

Coronaviruses

Article
Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
Binli Mao, Vu Thuy Khanh Le-Trilling, Kai Wang, Denise Mennerich, Jie Hu, Zhenyu Zhao, Jiaxin Zheng, Yingying Deng, Benjamin Katschinski, Shilei Xu, Guiji Zhang, Xuefei Cai, Yuan Hu, Jianwei Wang, Mengji Lu, Ailong Huang, Ni Tang, Mirko Trilling & Yong Lin
Pages: 483-497
Published online: 10 Feb 2022
AbstractforObatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
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Research Article

Article
Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men
Chin-Shiang Tsai, Kuan-Yin Lin, Bo-Huang Liou, Chien-Shun Chiou, Yi-Chun Lin, Yuan-Ti Lee, Chia-Jui Yang, Hung-Jen Tang, Ying-Shu Liao, Chun-Eng Liu, Chen-Hsiang Lee, Po-Liang Lu, Sung-Hsi Huang, Chien-Ching Hung, Wen-Chien Ko & on behalf of the Taiwan HIV Study Group
Pages: 498-506
Published online: 10 Feb 2022
AbstractforChanging epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Identification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence
Xinyi Wang, Huilin Zhao, Bingjie Wang, Ying Zhou, Yanlei Xu, Lulin Rao, Wenxiu Ai, Yinjuan Guo, Xiaocui Wu, Jingyi Yu, Longhua Hu, Lizhong Han, Shuying Chen, Liang Chen & Fangyou Yu
Pages: 507-518
Published online: 11 Feb 2022
AbstractforIdentification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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Coronaviruses

Article
hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs
Xi Zhang, Hin Chu, Kenn Ka-Heng Chik, Lei Wen, Huiping Shuai, Dong Yang, Yixin Wang, Yuxin Hou, Terrence Tsz-Tai Yuen, Jian-Piao Cai, Shuofeng Yuan, Feifei Yin, Kwok-Yung Yuen & Jasper Fuk-Woo Chan
Pages: 519-531
Published online: 10 Feb 2022
AbstractforhnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Methicillin-resistant Staphylococcus aureus in China: a multicentre longitudinal study and whole-genome sequencing
Bingjie Wang, Yanlei Xu, Huilin Zhao, Xinyi Wang, Lulin Rao, Yinjuan Guo, Xie Yi, Longhua Hu, Shuying Chen, Lizhong Han, Junying Zhou, Guoxiu Xiang, Long Hu, Liang Chen & Fangyou Yu
Pages: 532-542
Published online: 10 Feb 2022
AbstractforMethicillin-resistant Staphylococcus aureus in China: a multicentre longitudinal study and whole-genome sequencing | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 5821 Views
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Coronaviruses

Article
Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine
Lin-Lei Chen, Gilbert T. Chua, Lu Lu, Brian Pui-Chun Chan, Joshua Sung-Chih Wong, Calvin Chit-Kwong Chow, Tak-Ching Yu, Agnes Sze-Yin Leung, Shu-Yan Lam, Tak-Wai Wong, Hing-Wai Tsang, Ian Chi-Kei Wong, Kwok-Hung Chan, Kwok-Yung Yuen, Patrick Ip, Mike Yat-Wah Kwan & Kelvin Kai-Wang To
Pages: 543-547
Published online: 10 Feb 2022
AbstractforOmicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Article
Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants
Fengze Wang, Li Li, Yang Dou, Rui Shi, Xiaomin Duan, Hongchuan Liu, Jing Zhang, DanDan Liu, Jing Wu, Yang He, Jun Lan, Bai Lu, Hui Feng & Jinghua Yan
Pages: 548-551
Published online: 10 Feb 2022
AbstractforEtesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 3235 Views
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Letter
Possible recombination between two variants of concern in a COVID-19 patient
Yaqing He, Wentai Ma, Shengyuan Dang, Long Chen, Renli Zhang, Shujiang Mei, Xinyi Wei, Qiuying Lv, Bo Peng, Jiancheng Chen, Dongfeng Kong, Ying Sun, Xiujuan Tang, Weihua Wu, Zhigao Chen, Shimin Li, Jia Wan, Xuan Zou, Mingkun Li, Tiejian Feng, Lili Ren & Jianwei Wang
Pages: 552-555
Published online: 10 Feb 2022
AbstractforPossible recombination between two variants of concern in a COVID-19 patient | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Research Article

Article
Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China
Jieming Qu, Jing Zhang, Yu Chen, Yi Huang, Yusang Xie, Min Zhou, Yuping Li, Dongwei Shi, Jinfu Xu, Qiuyue Wang, Bei He, Ning Shen, Bin Cao, Danyang She, Yi Shi, Xin Su, Hua Zhou, Hong Fan, Feng Ye, Qiao Zhang, Xinlun Tian & Guoxiang Lai
Pages: 556-566
Published online: 10 Feb 2022
AbstractforAetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 8687 Views
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Coronaviruses

Article
Drastic decline in sera neutralization against SARS-CoV-2 Omicron variant in Wuhan COVID-19 convalescents
Chengbao Ma, Xianying Chen, Fanghua Mei, Qing Xiong, Qianyun Liu, Lianghui Dong, Chen Liu, Wenjing Zou, Faxian Zhan, Bing Hu, Yingle Liu, Fang Liu, Li Zhou, Junqiang Xu, Yongzhong Jiang, Ke Xu, Kun Cai, Yu Chen, Huan Yan & Ke Lan
Pages: 567-572
Published online: 16 Feb 2022
AbstractforDrastic decline in sera neutralization against SARS-CoV-2 Omicron variant in Wuhan COVID-19 convalescents | Full Text | References | PDF (1.7 MB) | EPUB
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Tuberculosis

Article
H2O2 concentration-dependent kinetics of gene expression: linking the intensity of oxidative stress and mycobacterial physiological adaptation
Mengying Wu, Wenyan Shan, Guo-Ping Zhao & Liang-Dong Lyu
Pages: 573-584
Published online: 16 Feb 2022
AbstractforH2O2 concentration-dependent kinetics of gene expression: linking the intensity of oxidative stress and mycobacterial physiological adaptation | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Coronaviruses

Article
Comparing real-life effectiveness of various COVID-19 vaccine regimens during the delta variant-dominant pandemic: a test-negative case-control study
Paskorn Sritipsukho, Thana Khawcharoenporn, Boonying Siribumrungwong, Pansachee Damronglerd, Nuntra Suwantarat, Araya Satdhabudha, Chanapai Chaiyakulsil, Phakatip Sinlapamongkolkul, Auchara Tangsathapornpong, Pornumpa Bunjoungmanee, Sira Nanthapisal, Chamnan Tanprasertkul, Naiyana Sritipsukho, Chatchai Mingmalairak, Anucha Apisarnthanarak & Pichaya Tantiyavarong
Pages: 585-592
Published online: 16 Feb 2022
AbstractforComparing real-life effectiveness of various COVID-19 vaccine regimens during the delta variant-dominant pandemic: a test-negative case-control study | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Research Article

Article
Metabolomic analysis reveals potential biomarkers and the underlying pathogenesis involved in Mycoplasma pneumoniae pneumonia
Jieqiong Li, Laurence Don Wai Luu, Xiaoxia Wang, XiaoDai Cui, Xiaolan Huang, Jin Fu, Xiong Zhu, Zhenjun Li, Yi Wang & Jun Tai
Pages: 593-605
Published online: 21 Feb 2022
AbstractforMetabolomic analysis reveals potential biomarkers and the underlying pathogenesis involved in Mycoplasma pneumoniae pneumonia | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
  • 4992 Views
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Article
Effect of pneumococcal conjugate vaccine availability on Streptococcus pneumoniae infections and genetic recombination in Zhejiang, China from 2009 to 2019
Xueqing Wu, Shanshan Zhao, Yan Jiang, Xi Xiang, Lihong Ge, Qiong Chen, Yanfei Wang, Jorge E. Vidal & Yunsong Yu
Pages: 606-615
Published online: 21 Feb 2022
AbstractforEffect of pneumococcal conjugate vaccine availability on Streptococcus pneumoniae infections and genetic recombination in Zhejiang, China from 2009 to 2019 | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 2474 Views
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Hepatitis

Article
Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines
Fahong Li, Yingying Deng, Shenyan Zhang, Beidi Zhu, Jun Wang, Jinyu Wang, Xueyu Wang, Zhenyu Zhao, Wanyu Deng, Richeng Mao, Zhongliang Shen, Jieliang Chen, Ruth Broering, Yong Lin, Mengji Lu & Jiming Zhang
Pages: 616-628
Published online: 21 Feb 2022
AbstractforHuman hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 4070 Views
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Coronaviruses

Article
CRISPR-based assay reveals SARS-CoV-2 RNA dynamic changes and redistribution patterns in non-human primate model
Zhen Huang, Lili Zhang, Christopher J. Lyon, Bo Ning, Brady M. Youngquist, Alex Niu, Brandon J. Beddingfield, Nicholas J. Maness, Nakhle S. Saba, Chen-Zhong Li, Chad J. Roy & Tony Y. Hu
Pages: 629-638
Published online: 21 Feb 2022
AbstractforCRISPR-based assay reveals SARS-CoV-2 RNA dynamic changes and redistribution patterns in non-human primate model | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2778 Views
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Research Article

Article
Safety and immunogenicity of a third-dose homologous BBIBP-CorV boosting vaccination: interim results from a prospective open-label study
Jingwen Ai, Yi Zhang, Haocheng Zhang, Qiran Zhang, Zhangfan Fu, Ke Lin, Jieyu Song, Yuanhan Zhao, Mingxiang Fan, Hongyu Wang, Yang Zhou, Xiaohua Chen, Chao Qiu & Wenhong Zhang
Pages: 639-647
Published online: 23 Feb 2022
AbstractforSafety and immunogenicity of a third-dose homologous BBIBP-CorV boosting vaccination: interim results from a prospective open-label study | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 5103 Views
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Antimicrobial Agents

Article
Emergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China
Xiaoyu Liu, Yarong Wu, Ying Zhu, Peiyao Jia, Xue Li, Xinmiao Jia, Wei Yu, Yujun Cui, Ruifu Yang, Wei Xia, Yingchun Xu & Qiwen Yang
Pages: 648-661
Published online: 03 Mar 2022
AbstractforEmergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 6699 Views
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Coronaviruses

Article
Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant
Natasha N. Gaudreault, Konner Cool, Jessie D. Trujillo, Igor Morozov, David A. Meekins, Chester McDowell, Dashzeveg Bold, Mariano Carossino, Velmurugan Balaraman, Dana Mitzel, Taeyong Kwon, Daniel W. Madden, Bianca Libanori Artiaga, Roman M. Pogranichniy, Gleyder Roman-Sosa, William C. Wilson, Udeni B. R. Balasuriya, Adolfo García-Sastre & Juergen A. Richt
Pages: 662-675
Published online: 24 Feb 2022
AbstractforSusceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 3186 Views
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Article
Plasma miRNA profile at COVID-19 onset predicts severity status and mortality
Asier Fernández-Pato, Ana Virseda-Berdices, Salvador Resino, Pablo Ryan, Oscar Martínez-González, Felipe Pérez-García, María Martin-Vicente, Daniel Valle-Millares, Oscar Brochado-Kith, Rafael Blancas, Amalia Martínez, Francisco C. Ceballos, Sofía Bartolome-Sánchez, Erick Joan Vidal-Alcántara, David Alonso, Natalia Blanca-López, Ignacio Ramirez Martinez-Acitores, Laura Martin-Pedraza, María Ángeles Jiménez-Sousa & Amanda Fernández-Rodríguez
Pages: 676-688
Published online: 27 Feb 2022
AbstractforPlasma miRNA profile at COVID-19 onset predicts severity status and mortality | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Article
Co-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong
Kin-Hang Kok, Shuk-Ching Wong, Wan-Mui Chan, Lei Wen, Allen Wing-Ho Chu, Jonathan Daniel Ip, Lam-Kwong Lee, Ivan Tak-Fai Wong, Hazel Wing-Hei Lo, Vincent Chi-Chung Cheng, Alex Yat-Man Ho, Bosco Hoi-Shiu Lam, Herman Tse, David Lung, Ken Ng Ho-Leung Ng, Albert Ka-Wing Au, Gilman Kit-Hang Siu & Kwok-Yung Yuen
Pages: 689-698
Published online: 27 Feb 2022
AbstractforCo-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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Article
Animal alphacoronaviruses found in human patients with acute respiratory illness in different countries.
Anastasia N. Vlasova, Teck-Hock Toh, Jeffrey Soon-Yit Lee, Yong Poovorawan, Phillip Davis, Marli S. P. Azevedo, John A. Lednicky, Linda J. Saif & Gregory C. Gray
Pages: 699-702
Published online: 27 Feb 2022
AbstractforAnimal alphacoronaviruses found in human patients with acute respiratory illness in different countries. | Full Text | References | PDF (925.2 KB) | EPUB
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Antimicrobial Agents

Article
Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance
Jochem B. Buil, Jason D. Oliver, Derek Law, Tim Baltussen, Jan Zoll, Margriet W. J. Hokken, Marlou Tehupeiory-Kooreman, Willem J. G. Melchers, Mike Birch & Paul E. Verweij
Pages: 703-714
Published online: 01 Mar 2022
AbstractforResistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 2937 Views
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Tuberculosis

Article
Modern Beijing sublineage of Mycobacterium tuberculosis shift macrophage into a hyperinflammatory status
Jingfeng Tong, Lu Meng, Cheng Bei, Qingyun Liu, Min Wang, TingTing Yang, Howard E. Takiff, Shuye Zhang, Qian Gao, Chuan Wang & Bo Yan
Pages: 715-724
Published online: 01 Mar 2022
AbstractforModern Beijing sublineage of Mycobacterium tuberculosis shift macrophage into a hyperinflammatory status | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 2816 Views
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Influenza infections

Letter
Infections with highly pathogenic avian influenza A virus (HPAIV) H5N8 in harbor seals at the German North Sea coast, 2021
Alexander Postel, Jacqueline King, Franziska K. Kaiser, Johanna Kennedy, Mara Sophie Lombardo, Wencke Reineking, Madeleine de le Roi, Timm Harder, Anne Pohlmann, Thomas Gerlach, Guus Rimmelzwaan, Simon Rohner, Lotte C. Striewe, Stephanie Gross, Luca A. Schick, Jana C. Klink, Katharina Kramer, Albert D. M. E. Osterhaus, Martin Beer, Wolfgang Baumgärtner, Ursula Siebert & Paul Becher
Pages: 725-729
Published online: 01 Mar 2022
AbstractforInfections with highly pathogenic avian influenza A virus (HPAIV) H5N8 in harbor seals at the German North Sea coast, 2021 | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 3720 Views
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Coronaviruses

Article
Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein
Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Xinrong Guo, Zhiyu Zhang, Jiawang Hou, Yuan Ding, Alex Cheng & Bin Wang
Pages: 730-740
Published online: 01 Mar 2022
AbstractforIdentification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 3299 Views
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Research Article

Article
Aedes Albopictus and Cache Valley virus: a new threat for virus transmission in New York State
Constentin Dieme, Joseph G. Maffei, Maryam Diarra, Cheri A. Koetzner, Lili Kuo, Kiet A. Ngo, Alan P. Dupuis II, Steven D. Zink, P. Bryon Backenson, Laura D. Kramer & Alexander T. Ciota
Pages: 741-748
Published online: 03 Mar 2022
AbstractforAedes Albopictus and Cache Valley virus: a new threat for virus transmission in New York State | Full Text | References | PDF (1.6 MB) | EPUB
  • 1841 Views
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Coronaviruses

Article
Three doses of an inactivation-based COVID-19 vaccine induces cross-neutralizing immunity against the SARS CoV-2 Omicron variant
Xiaoling Yu, Xiangrong Qi, Yu Cao, Peiyao Li, Li Lu, Pingping Wang, Yuchen Feng, Jie Yang, Huihui Wei, Lixian Guo, Mingyue Sun, Qiang Liu, Jing Lv & Yingmei Feng
Pages: 749-752
Published online: 03 Mar 2022
AbstractforThree doses of an inactivation-based COVID-19 vaccine induces cross-neutralizing immunity against the SARS CoV-2 Omicron variant | Full Text | References | PDF (931 KB) | EPUB | Supplemental
  • 3458 Views
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Letter
The SARS-CoV-2 inactivated vaccine enhances the broad neutralization against variants in individuals recovered from COVID-19 up to one year
Xinrong Zhou, Lin Cheng, Haiyan Wang, Xuejiao Liao, Miao Wang, Lanlan Wei, Shuo Song, Bing Zhou, Zhenghua Ma, Huimin Guo, Xiangyang Ge, Bin Ju & Zheng Zhang
Pages: 753-756
Published online: 03 Mar 2022
First Page PreviewforThe SARS-CoV-2 inactivated vaccine enhances the broad neutralization against variants in individuals recovered from COVID-19 up to one year | Full Text | References | PDF (474.1 KB) | EPUB | Supplemental
  • 2472 Views
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Influenza infections

Letter
Highly pathogenic avian influenza (A/H5N1) virus outbreaks in Lesotho, May 2021
Mabusetsa R.J. Makalo, William G. Dundon, Tirumala B.K. Settypalli, Sneha Datta, Charles E. Lamien, Giovanni Cattoli, Moeketsi S. Phalatsi, Relebohile J. Lepheana, Mpaliseng Matlali, Relebohile G. Mahloane, Marosi Molomo & Palesa C. Mphaka
Pages: 757-760
Published online: 10 Mar 2022
AbstractforHighly pathogenic avian influenza (A/H5N1) virus outbreaks in Lesotho, May 2021 | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2728 Views
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Research Article

Article
Usutu Virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus
Marie-France Martin, Ghizlane Maarifi, Hervé Abiven, Marine Seffals, Nicolas Mouchet, Cécile Beck, Charles Bodet, Nicolas Lévèque, Nathalie J. Arhel, Fabien P. Blanchet, Yannick Simonin & Sébastien Nisole
Pages: 761-774
Published online: 07 Mar 2022
AbstractforUsutu Virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 2450 Views
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Hepatitis

Article
A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients
Guangxin Yu, Ran Chen, Sujun Zheng, Yanna Liu, Jun Zou, Zhiqiang Gu, Bei Jiang, Qi Gao, Lizhong Dai, Jie Peng, Jie Wang & Fengmin Lu
Pages: 775-785
Published online: 10 Mar 2022
AbstractforA standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 4189 Views
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Coronaviruses

Letter
Viro-immunological evaluation in an immunocompromised patient with long-lasting SARS-CoV-2 infection
A. Mancon, A. Rizzo, D. Mileto, S. Grosso, A. Foschi, M. Cutrera, A. Capetti, I. Faggion, A. Anselmo, A. Monte, S. Fillo, G. Rizzardini, M. R. Gismondo & V. Micheli
Pages: 786-789
Published online: 10 Mar 2022
First Page PreviewforViro-immunological evaluation in an immunocompromised patient with long-lasting SARS-CoV-2 infection | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1562 Views
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Letter
Reduced neutralization of SARS-CoV-2 Omicron variant by BNT162b2 vaccinees’ sera: a preliminary evaluation
D. Mileto, V. Micheli, C. Fenizia, M. Cutrera, G. Gagliardi, A. Mancon, F. Bracchitta, A. De Silvestri, G. Rizzardini, A. Lombardi, M. Biasin & M. R. Gismondo
Pages: 790-792
Published online: 10 Mar 2022
First Page PreviewforReduced neutralization of SARS-CoV-2 Omicron variant by BNT162b2 vaccinees’ sera: a preliminary evaluation | Full Text | References | PDF (817.3 KB) | EPUB
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Article
The Protection of Naturally Acquired Antibodies Against Subsequent SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis
Qi Chen, Kongxin Zhu, Xiaohui Liu, Chunlan Zhuang, Xingcheng Huang, Yue Huang, Xingmei Yao, Jiali Quan, Hongyan Lin, Shoujie Huang, Yingying Su, Ting Wu, Jun Zhang & Ningshao Xia
Pages: 793-803
Published online: 12 Mar 2022
AbstractforThe Protection of Naturally Acquired Antibodies Against Subsequent SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Letter
COVID-19 mass vaccination – an illustration of the impact of syringe choice on the effectiveness of mass vaccination campaigns
Roseline Mazet, Luc Choisnard, Julien Leenhardt, Olivier Epaulard, Etienne Brudieu & Pierrick Bedouch
Pages: 804-806
Published online: 12 Mar 2022
AbstractforCOVID-19 mass vaccination – an illustration of the impact of syringe choice on the effectiveness of mass vaccination campaigns | Full Text | References | PDF (1,023 KB) | EPUB | Supplemental
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Influenza infections

Letter
Human infection with avian-origin H5N6 influenza a virus after exposure to slaughtered poultry
Jun Li, Yezhen Fang, Xiaofeng Qiu, Xinfen Yu, Shi Cheng, Na Li, Zhou Sun, Zhimin Ni & Haoqiu Wang
Pages: 807-810
Published online: 12 Mar 2022
AbstractforHuman infection with avian-origin H5N6 influenza a virus after exposure to slaughtered poultry | Full Text | References | PDF (774.5 KB) | EPUB | Supplemental
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Antimicrobial Agents

Review
Carbapenemase-producing Pseudomonas aeruginosa –an emerging challenge
Fred C. Tenover, David P. Nicolau & Christian M. Gill
Pages: 811-814
Published online: 12 Mar 2022
AbstractforCarbapenemase-producing Pseudomonas aeruginosa –an emerging challenge | Full Text | References | PDF (606.7 KB) | EPUB
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Research Article

Article
Metformin attenuated sepsis-related liver injury by modulating gut microbiota
Huoyan Liang, Heng Song, Xiaojuan Zhang, Gaofei Song, Yuze Wang, Xianfei Ding, Xiaoguang Duan, Lifeng Li, Tongwen Sun & Quancheng Kan
Pages: 815-828
Published online: 15 Mar 2022
AbstractforMetformin attenuated sepsis-related liver injury by modulating gut microbiota | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 8926 Views
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Coronaviruses

Article
Heterologous boosting with third dose of coronavirus disease recombinant subunit vaccine increases neutralizing antibodies and T cell immunity against different severe acute respiratory syndrome coronavirus 2 variants
Zhuxiang Zhao, Tingting Cui, Mingzhu Huang, Shuo Liu, Xiaoling Su, Guichang Li, Tao Song, Weidong Li, Nanshan Zhong, Miao Xu, Xiaoyun Yang, WeiJin Huang & Zhongfang Wang
Pages: 829-840
Published online: 15 Mar 2022
AbstractforHeterologous boosting with third dose of coronavirus disease recombinant subunit vaccine increases neutralizing antibodies and T cell immunity against different severe acute respiratory syndrome coronavirus 2 variants | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Research Article

Article
Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China
Xuemei Yang, Qiaoling Sun, Jiaping Li, Yu Jiang, Yi Li, Jianping Lin, Kaichao Chen, Edward Wai-Chi Chan, Rong Zhang & Sheng Chen
Pages: 841-849
Published online: 19 Mar 2022
AbstractforMolecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Characterization of a Clostridioides difficile outbreak caused by PCR ribotype 046, associated with increased mortality
Cecilia Magnusson, Sara Mernelius, Malin Bengnér, Torbjörn Norén, Lena Serrander, Sophie Forshell & Andreas Matussek
Pages: 850-859
Published online: 21 Mar 2022
AbstractforCharacterization of a Clostridioides difficile outbreak caused by PCR ribotype 046, associated with increased mortality | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Characterization and distribution of HIV-infected cells in semen
Lin Gao, Yan-Mei Jiao, Ping Ma, Lijun Sun, Hongxin Zhao, An-Liang Guo, Xing Fan, Chao Zhang, Jin-Wen Song, Ji-Yuan Zhang, Fengmin Lu & Fu-Sheng Wang
Pages: 860-872
Published online: 21 Mar 2022
AbstractforCharacterization and distribution of HIV-infected cells in semen | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 2607 Views
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Antimicrobial Agents

Article
Rifapentine is an entry and replication inhibitor against yellow fever virus both in vitro and in vivo
Xijing Qian, Bingan Wu, Hailin Tang, Zhenghan Luo, Zhenghao Xu, Songying Ouyang, Xiangliang Li, Jianfeng Xie, Zhigang Yi, Qibin Leng, Yan Liu, Zhongtian Qi & Ping Zhao
Pages: 873-884
Published online: 21 Mar 2022
AbstractforRifapentine is an entry and replication inhibitor against yellow fever virus both in vitro and in vivo | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 2614 Views
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Coronaviruses

Article
Adverse events of special interest following the use of BNT162b2 in adolescents: a population-based retrospective cohort study
Francisco Tsz Tsun Lai, Gilbert T. Chua, Edward Wai Wa Chan, Lei Huang, Mike Yat Wah Kwan, Tiantian Ma, Xiwen Qin, Celine Sze Ling Chui, Xue Li, Eric Yuk Fai Wan, Carlos King Ho Wong, Esther Wai Yin Chan, Ian Chi Kei Wong & Patrick Ip
Pages: 885-893
Published online: 21 Mar 2022
AbstractforAdverse events of special interest following the use of BNT162b2 in adolescents: a population-based retrospective cohort study | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Article
SARS-CoV-2 reinfection and COVID-19 severity
Nhu Ngoc Nguyen, Linda Houhamdi, Van Thuan Hoang, Jeremy Delerce, Léa Delorme, Philippe Colson, Philippe Brouqui, Pierre-Edouard Fournier, Didier Raoult & Philippe Gautret
Pages: 894-901
Published online: 21 Mar 2022
AbstractforSARS-CoV-2 reinfection and COVID-19 severity | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 7084 Views
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Article
A 1-year longitudinal study on COVID-19 convalescents reveals persistence of anti-SARS-CoV-2 humoral and cellular immunity
Yang Li, Xi Wang, Xu-Rui Shen, Rong Geng, Nan Xie, Jun-Feng Han, Qing-Miao Zhang, Zheng-Li Shi & Peng Zhou
Pages: 902-913
Published online: 30 Mar 2022
AbstractforA 1-year longitudinal study on COVID-19 convalescents reveals persistence of anti-SARS-CoV-2 humoral and cellular immunity | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Influenza infections

Article
A prophylactic effect of aluminium-based adjuvants against respiratory viruses via priming local innate immunity
Xin Wang, Xiaochen Yin, Boya Zhang, Chenfeng Liu, Yahua Lin, Xiaofen Huang, Yufang Li, Chenguang Shen, Weibin Zheng, Guofeng Fu, Junyu Chen, Yanling Wen, Wei Zhang, Bo-Sheng Pan, Mujin Fang, Zizheng Zheng, Zheng Zhang, Quan Yuan, Guo Fu, Shaowei Li, Jun Zhang, Yixin Chen, Ningshao Xia & Qinjian Zhao
Pages: 914-925
Published online: 28 Mar 2022
AbstractforA prophylactic effect of aluminium-based adjuvants against respiratory viruses via priming local innate immunity | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 3357 Views
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Coronaviruses

Article
Fusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants
Hanjun Zhao, Xinjie Meng, Zheng Peng, Hoiyan Lam, Chuyuan Zhang, Xinxin Zhou, Jasper Fuk-Woo Chan, Richard Yi Tsun Kao, Kelvin Kai-Wang To & Kwok-Yung Yuen
Pages: 926-937
Published online: 30 Mar 2022
AbstractforFusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Research Article

Article
Dissecting The role of Plasmodium metacaspase-2 in malaria gametogenesis and sporogony
Vandana Kumari, Kona Madhavinadha Prasad, Inderjeet Kalia, Gagandeep Sindhu, Rajnikant Dixit, Diwan S. Rawat, O. P. Singh, Agam P. Singh & Kailash C. Pandey
Pages: 938-955
Published online: 30 Mar 2022
AbstractforDissecting The role of Plasmodium metacaspase-2 in malaria gametogenesis and sporogony | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
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Article
Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups
Aapo Knuutila, Pauline Versteegen, Alex-Mikael Barkoff, Pieter van Gageldonk, Jussi Mertsola, Guy Berbers, Qiushui He & PERISCOPE Consortium
Pages: 956-963
Published online: 30 Mar 2022
AbstractforPertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups | Full Text | References | PDF (1,014.4 KB) | EPUB | Supplemental
  • 1648 Views
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Coronaviruses

Letter
A nasal omicron vaccine booster elicits potent neutralizing antibody response against emerging SARS-CoV-2 variants
Joy-Yan Lam, Yau-Yee Ng, Chun-Kit Yuen, Wan-Man Wong, Kwok-Yung Yuen & Kin-Hang Kok
Pages: 964-967
Published online: 30 Mar 2022
AbstractforA nasal omicron vaccine booster elicits potent neutralizing antibody response against emerging SARS-CoV-2 variants | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Research Article

Article
Concurrent pigeon paramyxovirus-1 and Acinetobacter baumannii infection in a fatal case of pneumonia
Xiaohui Zou, Lijun Suo, Yimin Wang, Hongyun Cao, Shengrui Mu, Chao Wu, Lizhen Yan, Xiaowei Qi, Jianwei Lu, Binghuai Lu, Yanyan Fan, Hui Li, Lixue Huang, Lili Ren, Bo Liu & Bin Cao
Pages: 968-977
Published online: 30 Mar 2022
AbstractforConcurrent pigeon paramyxovirus-1 and Acinetobacter baumannii infection in a fatal case of pneumonia | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3190 Views
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Coronaviruses

Article
RT-LAMP assay for rapid detection of the R203M mutation in SARS-CoV-2 Delta variant
Jianing Yang, Xuejiao Hu, Wenzhuo Wang, Yujing Yang, Xinqiang Zhang, Wei Fang, Lei Zhang, Shan Li & Bing Gu
Pages: 978-987
Published online: 30 Mar 2022
AbstractforRT-LAMP assay for rapid detection of the R203M mutation in SARS-CoV-2 Delta variant | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Research Article

Article
Adaptive evolution of West Nile virus facilitated increased transmissibility and prevalence in New York State
Sean M. Bialosuknia, Alan P. Dupuis II, Steven D. Zink, Cheri A. Koetzner, Joseph G. Maffei, Jennifer C. Owen, Hannah Landwerlen, Laura D. Kramer & Alexander T. Ciota
Pages: 988-999
Published online: 31 Mar 2022
AbstractforAdaptive evolution of West Nile virus facilitated increased transmissibility and prevalence in New York State | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2014 Views
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Article
Unprecedented outbreak of respiratory syncytial virus in Taiwan associated with ON1 variant emergence between 2010 and 2020
Wei-Hsuan Lin, Fang-Tzy Wu, Yi-Yin Chen, Chih-Wei Wang, Ho-Chen Lin, Ching-Chia Kuo, Wan-Chun Lai, Fang-Ju Lin, Wan-Tin Tiew, An-Li Tsai, Kuan-Ta Ho, Ting-Yu Kuo, Chung-Hao Li, Ching-Yi Wu, Yi-Jiun Pan, Kuo-Chien Tsao & Yu-Chia Hsieh
Pages: 1000-1009
Published online: 31 Mar 2022
AbstractforUnprecedented outbreak of respiratory syncytial virus in Taiwan associated with ON1 variant emergence between 2010 and 2020 | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 2561 Views
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Coronaviruses

Letter
Identification of a recombinant equine coronavirus in donkey, China
Peng-Fei Qi, Xing-Yi Gao, Jing-Kai Ji, Yan Zhang, Shao-Hua Yang, Kai-Hui Cheng, Ning Cui, Man-Ling Zhu, Tao Hu, Xuan Dong, Bin Yan, Chang-Fa Wang, Hong-Jun Yang, Wei-Feng Shi & Wei Zhang
Pages: 1010-1013
Published online: 04 Apr 2022
AbstractforIdentification of a recombinant equine coronavirus in donkey, China | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Correction

Correction
Correction
Page: 1014
Published online: 03 Apr 2022
CitationforCorrection | Full Text | PDF (114.8 KB) | EPUB
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Antimicrobial Agents

Article
Effective phage cocktail to combat the rising incidence of extensively drug-resistant Klebsiella pneumoniae sequence type 16
Willames M. B. S. Martins, Mei Li, Kirsty Sands, Michael H. Lenzi, Edward Portal, Jordan Mathias, Priscila P. Dantas, Roberta Migliavacca, James R. Hunter, Eduardo A. Medeiros, Ana C. Gales & Mark A. Toleman
Pages: 1015-1023
Published online: 07 Apr 2022
AbstractforEffective phage cocktail to combat the rising incidence of extensively drug-resistant Klebsiella pneumoniae sequence type 16 | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Coronaviruses

Article
Analysis of SARS-CoV-2 variants B.1.617: host tropism, proteolytic activation, cell–cell fusion, and neutralization sensitivity
Li Zhang, Qianqian Li, Jiajing Wu, Yuanling Yu, Yue Zhang, Jianhui Nie, Ziteng Liang, Zhimin Cui, Shuo Liu, Haixin Wang, Ruxia Ding, Fei Jiang, Tao Li, Lingling Nie, Qiong Lu, Jiayi Li, Lili Qin, Yinan Jiang, Yi Shi, Wenbo Xu, Weijin Huang & Youchun Wang
Pages: 1024-1036
Published online: 07 Apr 2022
AbstractforAnalysis of SARS-CoV-2 variants B.1.617: host tropism, proteolytic activation, cell–cell fusion, and neutralization sensitivity | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
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Article
Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2
Sven-Kevin Hotop, Susanne Reimering, Aditya Shekhar, Ehsaneddin Asgari, Ulrike Beutling, Christine Dahlke, Anahita Fathi, Fawad Khan, Marc Lütgehetmann, Rico Ballmann, Andreas Gerstner, Werner Tegge, Luka Cicin-Sain, Ursula Bilitewski, Alice C. McHardy & Mark Brönstrup
Pages: 1037-1048
Published online: 11 Apr 2022
AbstractforPeptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2 | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
Identification and genetic characterization of two conjugative plasmids that confer azithromycin resistance in Salmonella
Miaomiao Xie, Kaichao Chen, Edward Wai-chi Chan & Sheng Chen
Pages: 1049-1057
Published online: 11 Apr 2022
AbstractforIdentification and genetic characterization of two conjugative plasmids that confer azithromycin resistance in Salmonella | Full Text | References | PDF (2.3 MB) | EPUB
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Coronaviruses

Article
A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates
Yaling An, Shihua Li, Xiyue Jin, Jian-bao Han, Kun Xu, Senyu Xu, Yuxuan Han, Chuanyu Liu, Tianyi Zheng, Mei Liu, Mi Yang, Tian-Zhang Song, Baoying Huang, Li Zhao, Wen Wang, Ruhan A, Yingjie Cheng, Changwei Wu, Enqi Huang, Shilong Yang, Gary Wong, Yuhai Bi, Changwen Ke, Wenjie Tan, Jinghua Yan, Yong-Tang Zheng, Lianpan Dai & George F. Gao
Pages: 1058-1071
Published online: 11 Apr 2022
AbstractforA tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Article Commentary
Lessons learned from the fifth wave of COVID-19 in Hong Kong in early 2022
Pak-Hin Hinson Cheung, Chi-Ping Chan & Dong-Yan Jin
Pages: 1072-1078
Published online: 09 Apr 2022
First Page PreviewforLessons learned from the fifth wave of COVID-19 in Hong Kong in early 2022 | Full Text | References | PDF (1.4 MB) | EPUB
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Research Article

Article
Persistence of an epidemic cluster of Rhodotorula mucilaginosa in multiple geographic regions in China and the emergence of a 5-flucytosine resistant clone
Jing-Jing Huang, Xin-Fei Chen, Clement K.M. Tsui, Chong-Jie Pang, Zhi-Dong Hu, Yi Shi, Wei-Ping Wang, Lan-Ying Cui, Yu-Ling Xiao, Jie Gong, Xin Fan, Ying-Xing Li, Ge Zhang, Meng Xiao & Ying-Chun Xu
Pages: 1079-1089
Published online: 13 Apr 2022
AbstractforPersistence of an epidemic cluster of Rhodotorula mucilaginosa in multiple geographic regions in China and the emergence of a 5-flucytosine resistant clone | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 2525 Views
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Article
Epidemiology of extrapulmonary tuberculosis among pediatric inpatients in mainland China: a descriptive, multicenter study
Ping Chu, Yan Chang, Xuan Zhang, Shujing Han, Yaqiong Jin, Yongbo Yu, Yeran Yang, Guoshuang Feng, Xinyu Wang, Ying Shen, Xin Ni, Yongli Guo, Jie Lu & on behalf of the Futang Research Center of and Pediatric Development (FRCPD)
Pages: 1090-1102
Published online: 13 Apr 2022
AbstractforEpidemiology of extrapulmonary tuberculosis among pediatric inpatients in mainland China: a descriptive, multicenter study | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 3250 Views
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Coronaviruses

Article
Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters
C. J. Field, T. A. Heinly, D. R. Patel, D. G. Sim, E. Luley, S. L. Gupta, T. H. Vanderford, J. Wrammert & T. C. Sutton
Pages: 1103-1114
Published online: 18 Apr 2022
AbstractforImmune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 2686 Views
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Article
SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients
SARS-CoV-2 infection impairs islet function
Ningfei Ji, Mingshun Zhang, Liang Ren, Yunyun Wang, Bicheng Hu, Jie Xiang, Yingyun Gong, Chaojie Wu, Guoqiang Qu, Wenqiu Ding, Zhiqiang Yin, Shan Li, Zhengxia Wang, Lianzheng Zhou, Xueqin Chen, Yuan Ma, Jinhai Tang, Yun Liu, Liang Liu & Mao Huang
Pages: 1115-1125
Published online: 18 Apr 2022
AbstractforSARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients | Full Text | References | PDF (3.3 MB) | EPUB
  • 3540 Views
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Article
Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV
Ling Ao, Ting Lu, Yu Cao, Zhiwei Chen, Yuting Wang, Zisheng Li, Xingqian Ren, Pan Xu, Mingli Peng, Min Chen, Gaoli Zhang, Dejuan Xiang, Dachuan Cai, Peng Hu, Xiaofeng Shi, Dazhi Zhang & Hong Ren
Pages: 1126-1134
Published online: 18 Apr 2022
AbstractforSafety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 3648 Views
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Article
SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner
Yun-Qi Zhou, Ke Wang, Xue-Yan Wang, Hong-Yong Cui, Yongxiang Zhao, Ping Zhu & Zhi-Nan Chen
Pages: 1135-1144
Published online: 18 Apr 2022
AbstractforSARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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Article
Transcriptomic analysis of the innate immune signatures of a SARS-CoV-2 protein subunit vaccine ZF2001 and an mRNA vaccine RRV
Qian Wang, Ziyang Song, Jinghuan Yang, Qian He, Qunying Mao, Yu Bai, Jianyang Liu, Chaoqiang An, Xujia Yan, Bopei Cui, Lifang Song, Dong Liu, Miao Xu & Zhenglun Liang
Pages: 1145-1153
Published online: 18 Apr 2022
AbstractforTranscriptomic analysis of the innate immune signatures of a SARS-CoV-2 protein subunit vaccine ZF2001 and an mRNA vaccine RRV | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Article
Clinical efficacy and safety of interleukin-6 receptor antagonists (tocilizumab and sarilumab) in patients with COVID-19: a systematic review and meta-analysis
Su-Yeon Yu, Dae-Hyup Koh, Miyoung Choi, Seungeun Ryoo, Kyungmin Huh, Joon Sup Yeom & Young Kyung Yoon
Pages: 1154-1165
Published online: 18 Apr 2022
AbstractforClinical efficacy and safety of interleukin-6 receptor antagonists (tocilizumab and sarilumab) in patients with COVID-19: a systematic review and meta-analysis | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article
The novel fosfomycin resistance gene fosY is present on a genomic island in CC1 methicillin-resistant Staphylococcus aureus
Yiyi Chen, Shujuan Ji, Lu Sun, Haiping Wang, Feiteng Zhu, Mengzhen Chen, Hemu Zhuang, Zhengan Wang, Shengnan Jiang, Yunsong Yu & Yan Chen
Pages: 1166-1173
Published online: 20 Apr 2022
AbstractforThe novel fosfomycin resistance gene fosY is present on a genomic island in CC1 methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Influenza infections

Article
Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China
Wenli Gu, Jianzhong Shi, Pengfei Cui, Cheng Yan, Yaping Zhang, Congcong Wang, Yuancheng Zhang, Xin Xing, Xianying Zeng, Liling Liu, Guobin Tian, Yasuo Suzuki, Chengjun Li, Guohua Deng & Hualan Chen
Pages: 1174-1185
Published online: 25 Apr 2022
AbstractforNovel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 5567 Views
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Coronaviruses

Letter
The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2
Xiaolong Tian, Xiaoyi Zhu, Wenping Song, Zhenlin Yang, Yanling Wu & Tianlei Ying
Pages: 1186-1190
Published online: 25 Apr 2022
AbstractforThe prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2 | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 1906 Views
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Influenza infections

Article
Pandemic influenza A (H1N1) virus causes abortive infection of primary human T cells
Jiapei Yu, Hui Li, Ju Jia, Zhisheng Huang, Shuai Liu, Ying Zheng, Shengrui Mu, Xiaoyan Deng, Xiaohui Zou, Yeming Wang, Xiao Shang, Dan Cui, Lixue Huang, Xiaoxuan Feng, William J. Liu & Bin Cao
Pages: 1191-1204
Published online: 25 Apr 2022
AbstractforPandemic influenza A (H1N1) virus causes abortive infection of primary human T cells | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Coronaviruses

Article
Assessing the transition of COVID-19 burden towards the young population while vaccines are rolled out in China*
Jun Cai, Juan Yang, Xiaowei Deng, Cheng Peng, Xinhua Chen, Qianhui Wu, Hengcong Liu, Juanjuan Zhang, Wen Zheng, Junyi Zou, Zeyao Zhao, Marco Ajelli & Hongjie Yu
Pages: 1205-1214
Published online: 25 Apr 2022
AbstractforAssessing the transition of COVID-19 burden towards the young population while vaccines are rolled out in China* | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2874 Views
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Research Article

Article
Mapping the risk distribution of Borrelia burgdorferi sensu lato in China from 1986 to 2020: a geospatial modelling analysis
Tian-Le Che, Bao-Gui Jiang, Qiang Xu, Yu-Qi Zhang, Chen-Long Lv, Jin-Jin Chen, Ying-Jie Tian, Yang Yang, Simon I. Hay, Wei Liu & Li-Qun Fang
Pages: 1215-1226
Published online: 28 Apr 2022
AbstractforMapping the risk distribution of Borrelia burgdorferi sensu lato in China from 1986 to 2020: a geospatial modelling analysis | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 2824 Views
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Hepatitis

Article
Sexually-transmitted hepatitis C virus reinfections among people living with HIV in Taiwan: the emerging role of genotype 6
Guan-Jhou Chen, Hsin-Yun Sun, Sui-Yuan Chang, Li-Hsin Su, Yi-Ting Chen, Szu-Min Hsieh, Wan-Da Liu, Wang-Huei Sheng, Yu-Shan Huang, Kuan-Yin Lin, Yi-Ching Su, Wen-Chun Liu & Chien-Ching Hung
Pages: 1227-1235
Published online: 28 Apr 2022
AbstractforSexually-transmitted hepatitis C virus reinfections among people living with HIV in Taiwan: the emerging role of genotype 6 | Full Text | References | PDF (1.5 MB) | EPUB
  • 2053 Views
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Antimicrobial Agents

Article
MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria
Siyuan Feng, Wanfei Liang, Jiachen Li, Yong Chen, Dianrong Zhou, Lujie Liang, Daixi Lin, Yaxin Li, Hui Zhao, Huihui Du, Min Dai, Li-Na Qin, Fan Bai, Yohei Doi, Lan-Lan Zhong & Guo-bao Tian
Pages: 1236-1249
Published online: 28 Apr 2022
AbstractforMCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 4182 Views
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Influenza infections

Article
Exploring surface water as a transmission medium of avian influenza viruses – systematic infection studies in mallards
Ann Kathrin Ahrens, Hans-Christoph Selinka, Thomas C. Mettenleiter, Martin Beer & Timm C. Harder
Pages: 1250-1261
Published online: 03 May 2022
AbstractforExploring surface water as a transmission medium of avian influenza viruses – systematic infection studies in mallards | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 2820 Views
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Coronaviruses

Article
COVID-19 breakthrough infections and humoral immune response among BNT162b2 vaccinated healthcare workers in Malaysia
Su Lan Yang, Adiratna Mat Ripen, Chin Tho Leong, Jen Ven Lee, Chia How Yen, Avinash Kumar Chand, Karina Koh, Nur Aisyah Binti Abdul Rahim, Varaalakshmy Gokilavanan, Nik Nur Eliza binti Mohamed, Raj Kumar A/L. Sevalingam, Nadirah Sulaiman, Ahmad Kamil bin Ab Razak, Nurul Haslinda binti Mohd Nor, Mei Kuan Pong, Ket Yan Tai, Valerie Toh, Yuan Liang Woon & Kalaiarasu M. Peariasamy
Pages: 1262-1271
Published online: 03 May 2022
AbstractforCOVID-19 breakthrough infections and humoral immune response among BNT162b2 vaccinated healthcare workers in Malaysia | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 5049 Views
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Research Article

Article
Risk assessment of urban yellow fever virus transmission in Kenya: is Aedes aegypti an efficient vector?
Sheila B. Agha, David P. Tchouassi, Michael J. Turell, Armanda D.S. Bastos & Rosemary Sang
Pages: 1272-1280
Published online: 05 May 2022
AbstractforRisk assessment of urban yellow fever virus transmission in Kenya: is Aedes aegypti an efficient vector? | Full Text | References | PDF (1.3 MB) | EPUB
  • 2306 Views
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Article
Outer membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae
Yuneng Hua, Jingyu Wang, Mei Huang, Yiyi Huang, Ruyi Zhang, Fan Bu, Biao Yang, Juanjiang Chen, Xiaomin Lin, Xiumei Hu, Lei Zheng & Qian Wang
Pages: 1281-1292
Published online: 23 May 2022
AbstractforOuter membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 5088 Views
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Antimicrobial Agents

Article
N-chlorotaurine is highly active against respiratory viruses including SARS-CoV-2 (COVID-19) in vitro
Michaela Lackner, Annika Rössler, André Volland, Marlena Nastassja Stadtmüller, Brigitte Müllauer, Zoltan Banki, Johannes Ströhle, Angela Luttick, Jennifer Fenner, Bettina Sarg, Leopold Kremser, Paul Tone, Heribert Stoiber, Dorothee von Laer, Thorsten Wolff, Carsten Schwarz & Markus Nagl
Pages: 1293-1307
Published online: 23 May 2022
AbstractforN-chlorotaurine is highly active against respiratory viruses including SARS-CoV-2 (COVID-19) in vitro | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
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Research Article

Article
Invasive listeriosis outbreaks and salmon products: a genomic, epidemiological study
Raskit Lachmann, Sven Halbedel, Stefanie Lüth, Alexandra Holzer, Marlen Adler, Ariane Pietzka, Sascha Al Dahouk, Klaus Stark, Antje Flieger, Sylvia Kleta & Hendrik Wilking
Pages: 1308-1315
Published online: 23 May 2022
AbstractforInvasive listeriosis outbreaks and salmon products: a genomic, epidemiological study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 4914 Views
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Coronaviruses

Article
Impact of prior vaccination on clinical outcomes of patients with COVID-19
Woo Jung Seo, Jiyeon Kang, Hyung Koo Kang, So Hee Park, Hyeon-Kyoung Koo, Hye Kyeong Park, Sung-Soon Lee, Je Eun Song, Yee Gyung Kwak & Jieun Kang
Pages: 1316-1324
Published online: 23 May 2022
AbstractforImpact of prior vaccination on clinical outcomes of patients with COVID-19 | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Research Article

Article
Evidence of pediatric sepsis caused by a drug resistant Lactococcus garvieae contaminated platelet concentrate
Luna Colagrossi, Valentino Costabile, Rossana Scutari, Marilena Agosta, Manuela Onori, Livia Mancinelli, Barbara Lucignano, Andrea Onetti Muda, Giada Del Baldo, Angela Mastronuzzi, Franco Locatelli, Guglielmo Trua, Mauro Montanari, Claudia Alteri, Paola Bernaschi & Carlo Federico Perno
Pages: 1325-1334
Published online: 23 May 2022
AbstractforEvidence of pediatric sepsis caused by a drug resistant Lactococcus garvieae contaminated platelet concentrate | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article Commentary

Article Commentary
Molecular epidemiology of human Borna disease virus 1 infection revisited
Liv Bode, Yujie Guo & Peng Xie
Pages: 1335-1338
Published online: 23 May 2022
AbstractforMolecular epidemiology of human Borna disease virus 1 infection revisited | Full Text | References | PDF (1.8 MB) | EPUB
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Research Article

Article
Detection of human, porcine and canine picornaviruses in municipal sewage sludge using pan-enterovirus amplicon-based long-read Illumina sequencing
Temitope O. C. Faleye, Erin M. Driver, Devin A. Bowes, Rochelle H. Holm, Daymond Talley, Ray Yeager, Aruni Bhatnagar, Ted Smith, Arvind Varsani, Rolf U. Halden & Matthew Scotch
Pages: 1339-1342
Published online: 23 May 2022
AbstractforDetection of human, porcine and canine picornaviruses in municipal sewage sludge using pan-enterovirus amplicon-based long-read Illumina sequencing | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 2006 Views
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Coronaviruses

Letter
Real-world effectiveness of homologous and heterologous BNT162b2, CoronaVac, and AZD1222 booster vaccination against Delta and Omicron SARS-CoV-2 infection
Jing Lian Suah, Boon Hwa Tng, Peter Seah Keng Tok, Masliyana Husin, Thevesh Thevananthan, Kalaiarasu M. Peariasamy & Sheamini Sivasampu
Pages: 1343-1345
Published online: 23 May 2022
AbstractforReal-world effectiveness of homologous and heterologous BNT162b2, CoronaVac, and AZD1222 booster vaccination against Delta and Omicron SARS-CoV-2 infection | Full Text | References | PDF (943.1 KB) | EPUB | Supplemental
  • 6266 Views
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Research Article

Article
Identification of a novel drug-resistant community-acquired Nocardia spp. in a patient with bronchiectasis
Zhengtu Li, Yongming Li, Shaoqiang Li, Zhun Li, Ying Mai, Jing Cheng, Danhong Su, Yangqing Zhan, Nanshan Zhong & Feng Ye
Pages: 1346-1355
Published online: 23 May 2022
AbstractforIdentification of a novel drug-resistant community-acquired Nocardia spp. in a patient with bronchiectasis | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 2339 Views
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Article
Solely HBsAg intrauterine exposure accelerates HBV clearance by promoting HBs-specific immune response in the mouse pups
Jing Ning, Jianwen Wang, Huiling Zheng, Siwen Peng, Tianhao Mao, Lu Wang, Guangxin Yu, Jia Liu, Shuang Liu, Ting Zhang, Shigang Ding, Fengmin Lu & Xiangmei Chen
Pages: 1356-1370
Published online: 23 May 2022
AbstractforSolely HBsAg intrauterine exposure accelerates HBV clearance by promoting HBs-specific immune response in the mouse pups | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 5198 Views
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Coronaviruses

Review
Virus-host interaction networks as new antiviral drug targets for IAV and SARS-CoV-2
Na Chen, Baoge Zhang, Lulu Deng, Bing Liang & Jihui Ping
Pages: 1371-1389
Published online: 23 May 2022
AbstractforVirus-host interaction networks as new antiviral drug targets for IAV and SARS-CoV-2 | Full Text | References | PDF (2.2 MB) | EPUB
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Letter

Letter
Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever
Stephen R. Welch, Sarah C. Genzer, JoAnn D. Coleman-McCray, Jessica R. Harmon, Florine E.M. Scholte, Joel M. Montgomery, Christina F. Spiropoulou & Jessica R. Spengler
Pages: 1390-1393
Published online: 23 May 2022
AbstractforViral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1291 Views
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Coronaviruses

Article
Understanding the impact of rapid antigen tests on SARS-CoV-2 transmission in the fifth wave of COVID-19 in Hong Kong in early 2022
Zhanwei Du, Linwei Tian & Dong-Yan Jin
Pages: 1394-1401
Published online: 23 May 2022
AbstractforUnderstanding the impact of rapid antigen tests on SARS-CoV-2 transmission in the fifth wave of COVID-19 in Hong Kong in early 2022 | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Research Article

Article
Virulence adaption to environment promotes the age-dependent nasal colonization of Staphylococcus aureus
Na Zhao, Danhong Cheng, Ziyu Yang, Yao Liu, Yanan Wang, Ying Jian, Hua Wang, Min Li, Taeok Bae & Qian Liu
Pages: 1402-1415
Published online: 23 May 2022
AbstractforVirulence adaption to environment promotes the age-dependent nasal colonization of Staphylococcus aureus | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 2065 Views
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Article
Molecular diagnostics and next-generation sequencing reveal real etiological characteristics of invasive Salmonella infection in febrile illness in Freetown, Sierra Leone
Jiayong Zhao, Xin Lu, Alie Tie, Esther Ngegba, Lili Wang, Lu Sun, Ying Liang, Michael K. Abdulai, Sununu Bah, Gang Wang, Xiaoping Dong, Doris Harding & Biao Kan
Pages: 1416-1424
Published online: 23 May 2022
AbstractforMolecular diagnostics and next-generation sequencing reveal real etiological characteristics of invasive Salmonella infection in febrile illness in Freetown, Sierra Leone | Full Text | References | PDF (1.7 MB) | EPUB
  • 2219 Views
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Influenza infections

Article
Assessing potential pathogenicity of novel highly pathogenic avian influenza (H5N6) viruses isolated from Mongolian wild duck feces using a mouse model
Bao Tuan Duong, Duc Duong Than, Ulaankhuu Ankhanbaatar, Delgerzul Gombo-Ochir, Gansukh Shura, Amartuvshin Tsolmon, Chris Ka Pun Mok, Ganzorig Basan, Seon Ju Yeo & Hyun Park
Pages: 1425-1434
Published online: 25 May 2022
AbstractforAssessing potential pathogenicity of novel highly pathogenic avian influenza (H5N6) viruses isolated from Mongolian wild duck feces using a mouse model | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 2489 Views
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Antimicrobial Agents

Letter
Triazole-resistant Aspergillus luchuensis, an industrially important black Aspergillus spp. used in fermentation in East Asia, isolated from the patient with invasive pulmonary aspergillosis in China
Qiqi Wang, Yun Li, Yanming Li, Nir Osherov, Gustavo H. Goldman, Paul E. Verweij, Bo Zheng, Ruoyu Li, Wei Chen, Tianyu Liang, Zhe Wan & Wei Liu
Pages: 1435-1438
Published online: 26 May 2022
AbstractforTriazole-resistant Aspergillus luchuensis, an industrially important black Aspergillus spp. used in fermentation in East Asia, isolated from the patient with invasive pulmonary aspergillosis in China | Full Text | References | PDF (860.2 KB) | EPUB
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Research Article

Article
Recombinant adeno-associated virus serotype 9 AAV-RABVG expressing a Rabies Virus G protein confers long-lasting immune responses in mice and non-human primates
Chenjuan Shi, Li Tian, Wenwen Zheng, Yelei Zhu, Peilu Sun, Lele Liu, Wenkai Liu, Yanyan Song, Xianzhu Xia, Xianghong Xue & Xuexing Zheng
Pages: 1439-1451
Published online: 26 May 2022
AbstractforRecombinant adeno-associated virus serotype 9 AAV-RABVG expressing a Rabies Virus G protein confers long-lasting immune responses in mice and non-human primates | Full Text | References | PDF (4 MB) | EPUB
  • 2626 Views
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Influenza infections

Article
Pathogenesis and transmission of human seasonal and swine-origin A(H1) influenza viruses in the ferret model
Joanna A. Pulit-Penaloza, Nicole Brock, Joyce Jones, Jessica A. Belser, Yunho Jang, Xiangjie Sun, Sharmi Thor, Claudia Pappas, Natosha Zanders, Terrence M. Tumpey, C. Todd Davis & Taronna R. Maines
Pages: 1452-1459
Published online: 01 Jun 2022
AbstractforPathogenesis and transmission of human seasonal and swine-origin A(H1) influenza viruses in the ferret model | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Research Article

Article
Genomic dissection of the microevolution of Australian epidemic Bordetella pertussis
Zheng Xu, Dalong Hu, Laurence Don Wai Luu, Sophie Octavia, Anthony D. Keil, Vitali Sintchenko, Mark M. Tanaka, Frits R. Mooi, Jenny Robson & Ruiting Lan
Pages: 1460-1473
Published online: 01 Jun 2022
AbstractforGenomic dissection of the microevolution of Australian epidemic Bordetella pertussis | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1738 Views
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Article
Analysis of the evolution, infectivity and antigenicity of circulating rabies virus strains
Meina Cai, Haizhou Liu, Fei Jiang, Yeqing Sun, Wenbo Wang, Yimeng An, Mengyi Zhang, Xueli Li, Di Liu, Yuhua Li, Yongxin Yu, Weijin Huang & Youchun Wang
Pages: 1474-1487
Published online: 01 Jun 2022
AbstractforAnalysis of the evolution, infectivity and antigenicity of circulating rabies virus strains | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 2937 Views
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Coronaviruses

Article
ACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants
Bolun Wang, Junxuan Zhao, Shuo Liu, Jingyuan Feng, Yufeng Luo, Xinyu He, Yanmin Wang, Feixiang Ge, Junyi Wang, Buqing Ye, Weijin Huang, Xiaochen Bo, Youchun Wang & Jianzhong Jeff Xi
Pages: 1488-1499
Published online: 01 Jun 2022
AbstractforACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 2728 Views
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Article
Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection
Huang Liang, Peiyan Zheng, Qian Wang, Yijun Deng, Dan Liang, Haisu Yi, Yuanyi Cheng, Xinwei Zhao, Jing Ma, Yidong Yang, Peiyu Hu, Pingqian Zheng, Yudi Zhang, Shuangshuang Huang, Xiancheng Lin, Changwen Ke, Xuefeng Niu, Baoqing Sun & Ling Chen
Pages: 1500-1507
Published online: 02 Jun 2022
AbstractforBroad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 2113 Views
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Research Article

Article
Mycoplasma pneumoniae triggers pneumonia epidemic in autumn and winter in Beijing: a multicentre, population-based epidemiological study between 2015 and 2020
Xue Wang, Maozhong Li, Ming Luo, Qin Luo, Lu Kang, Hui Xie, Yiting Wang, Xiali Yu, Aihua Li, Mei Dong, Fang Huang & Cheng Gong
Pages: 1508-1517
Published online: 02 Jun 2022
AbstractforMycoplasma pneumoniae triggers pneumonia epidemic in autumn and winter in Beijing: a multicentre, population-based epidemiological study between 2015 and 2020 | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 3328 Views
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Coronaviruses

Article
An open, prospective cohort study of VV116 in Chinese participants infected with SARS-CoV-2 omicron variants
Yinzhong Shen, Jingwen Ai, Na Lin, Haocheng Zhang, Yang Li, Hongyu Wang, Sen Wang, Zhen Wang, Tao Li, Feng Sun, Zhenyu Fan, Liqun Li, Yunfei Lu, Xianmin Meng, Hong Xiao, Huiliang Hu, Yun Ling, Feng Li, Hongdi Li, Chunmei Xi, Liping Gu, Wenhong Zhang & Xiaohong Fan
Pages: 1518-1523
Published online: 02 Jun 2022
AbstractforAn open, prospective cohort study of VV116 in Chinese participants infected with SARS-CoV-2 omicron variants | Full Text | References | PDF (802.7 KB) | EPUB
  • 12361 Views
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Article
The Third dose of CoronVac vaccination induces broad and potent adaptive immune responses that recognize SARS-CoV-2 Delta and Omicron variants
Yuxin Chen, Lin Chen, Shengxia Yin, Yue Tao, Liguo Zhu, Xin Tong, Minxin Mao, Ming Li, Yawen Wan, Jun Ni, Xiaoyun Ji, Xianchi Dong, Jie Li, Rui Huang, Ya Shen, Han Shen, Changjun Bao & Chao Wu
Pages: 1524-1536
Published online: 02 Jun 2022
AbstractforThe Third dose of CoronVac vaccination induces broad and potent adaptive immune responses that recognize SARS-CoV-2 Delta and Omicron variants | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 3876 Views
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Article
Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS
María C. García-Hidalgo, Jessica González, Iván D. Benítez, Paola Carmona, Sally Santisteve, Manel Pérez-Pons, Anna Moncusí-Moix, Clara Gort-Paniello, Fátima Rodríguez-Jara, Marta Molinero, Thalia Belmonte, Gerard Torres, Gonzalo Labarca, Estefania Nova-Lamperti, Jesús Caballero, Jesús F. Bermejo-Martin, Adrián Ceccato, Laia Fernández-Barat, Ricard Ferrer, Dario Garcia-Gasulla, Rosario Menéndez, Ana Motos, Oscar Peñuelas, Jordi Riera, Antoni Torres, Ferran Barbé, David de Gonzalo-Calvo & on behalf of the CIBERESUCICOVID Project (COV20/00110, ISCIII)
Pages: 1537-1549
Published online: 04 Jun 2022
AbstractforIdentification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 3517 Views
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Letter
mRNA based vaccines provide broad protection against different SARS-CoV-2 variants of concern
Haomeng Wang, Zhao Chen, Zhenghua Wang, Jin Li, Zhihong Yan, Jinbo Yuan, Airu Zhu, Lan Chen, Ye Liu, Chenlong Hu, Ali Zhu, Guowei Li, Yuehu Li, Jie Deng, Liqiao Ma, Xiuwen Sui, Wei Miao, Junqiang Li, Xiuyu Zheng, Jinhua Piao, Yanfeng Yao, Juhong Rao, Chao Shan, Zhiming Yuan, Jincun Zhao & Tao Zhu
Pages: 1550-1553
Published online: 04 Jun 2022
AbstractformRNA based vaccines provide broad protection against different SARS-CoV-2 variants of concern | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Research Article

Article
Gene essentiality profiling reveals a novel determinant of stresses preventing protein aggregation in Salmonella
Zuoqiang Wang, Siqi Zhu, Congcong Li, Lin Lyu, Jingchen Yu, Danni Wang, Zhihong Xu, Jinjing Ni, Beile Gao, Jie Lu & Yu-Feng Yao
Pages: 1554-1571
Published online: 04 Jun 2022
AbstractforGene essentiality profiling reveals a novel determinant of stresses preventing protein aggregation in Salmonella | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2511 Views
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Article
Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain
Hailong Li, Xiaoxu Han, Wei Du, Yang Meng, Yanjian Li, Tianshu Sun, Qiaojing Liang, Chao Li, Chenhao Suo, Xindi Gao, Yu Qiu, Wen Tian, Minghui An, Hui Zhang, Yajing Fu, Xiaolin Li, Tian Lan, Sheng Yang, Zining Zhang, Wenqing Geng, Chen Ding & Hong Shang
Pages: 1572-1585
Published online: 04 Jun 2022
AbstractforComparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 2848 Views
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Article
Down-regulated cylindromatosis enhances NF-κB activation and aggravates inflammation in HBV-ACLF patients
Xueyun Zhang, Yao Zhang, Pu Zhou, Jingwen Ai, Xiaoqin Liu, Quanbao Zhang, Zhengxin Wang, Hongyan Wang, Wenhong Zhang, Jiming Zhang & Yuxian Huang
Pages: 1586-1601
Published online: 07 Jun 2022
AbstractforDown-regulated cylindromatosis enhances NF-κB activation and aggravates inflammation in HBV-ACLF patients | Full Text | References | PDF (5.1 MB) | EPUB | Supplemental
  • 4177 Views
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Antimicrobial Agents

Article Commentary
Comments on the published meta-analysis of antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries
Zahra Hadi, Forough Goodarzi, Amine Dalir & Mohammad Sholeh
Pages: 1602-1603
Published online: 10 Jun 2022
CitationforComments on the published meta-analysis of antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries | Full Text | References | PDF (232.3 KB) | EPUB
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Zika

Article
Identification and characterization of key residues in Zika virus envelope protein for virus assembly and entry
Xiao Ma, Zhenghong Yuan & Zhigang Yi
Pages: 1604-1620
Published online: 10 Jun 2022
AbstractforIdentification and characterization of key residues in Zika virus envelope protein for virus assembly and entry | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
  • 2136 Views
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Article
Zika virus infects human osteoclasts and blocks differentiation and bone resorption
Noreen Mumtaz, Marijke Koedam, Johannes P. T. M. van Leeuwen, Marion P. G. Koopmans, Bram C. J. van der Eerden & Barry Rockx
Pages: 1621-1634
Published online: 14 Jun 2022
AbstractforZika virus infects human osteoclasts and blocks differentiation and bone resorption | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 1727 Views
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Ebola

Article
Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques
Courtney Woolsey, Alyssa C. Fears, Viktoriya Borisevich, Krystle N. Agans, Natalie S. Dobias, Abhishek N. Prasad, Daniel J. Deer, Joan B. Geisbert, Karla A. Fenton, Thomas W. Geisbert & Robert W. Cross
Pages: 1635-1646
Published online: 14 Jun 2022
AbstractforNatural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 2592 Views
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Research Article

Article
Comparison of laboratory and immune characteristics of the initial and second phase of tick-borne encephalitis
Petra Bogovič, Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, Katarina Resman Rus, Klemen Strle & Franc Strle
Pages: 1647-1656
Published online: 15 Jun 2022
AbstractforComparison of laboratory and immune characteristics of the initial and second phase of tick-borne encephalitis | Full Text | References | PDF (1.4 MB) | EPUB
  • 2001 Views
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Article
Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins
Tengcheng Que, Jing Li, Yugan He, Panyu Chen, Wei Lin, Meihong He, Lei Yu, Aiqiong Wu, Luohao Tan, Yingjiao Li, Yanling Hu & Yigang Tong
Pages: 1657-1663
Published online: 20 Jun 2022
AbstractforHuman parainfluenza 3 and respiratory syncytial viruses detected in pangolins | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 2062 Views
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Hepatitis

Article
Hepatitis C microelimination among people living with HIV in Taiwan
Guan-Jhou Chen, Shu-Yuan Ho, Li-Hsin Su, Sui-Yuan Chang, Szu-Min Hsieh, Wang-Huei Sheng, Wang-Da Liu, Yu-Shan Huang, Kuan-Yin Lin, Yi-Ting Chen, Yi-Ching Su, Wen-Chun Liu, Hsin-Yun Sun & Chien-Ching Hung
Pages: 1664-1671
Published online: 20 Jun 2022
AbstractforHepatitis C microelimination among people living with HIV in Taiwan | Full Text | References | PDF (2 MB) | EPUB
  • 1890 Views
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Research Article

Article
Effect of genomic variations in severe fever with thrombocytopenia syndrome virus on the disease lethality
Zi-Niu Dai, Xue-Fang Peng, Jia-Chen Li, Jing Zhao, Yong-Xiang Wu, Xin Yang, Tong Yang, Shao-Fei Zhang, Ke Dai, Xiu-Gang Guan, Chun Yuan, Zhen-Dong Yang, Ning Cui, Qing-Bin Lu, Yong Huang, Hang Fan, Xiao-Ai Zhang, Geng-Fu Xiao, Ke Peng, Lei-Ke Zhang, Wei Liu & Hao Li
Pages: 1672-1682
Published online: 20 Jun 2022
AbstractforEffect of genomic variations in severe fever with thrombocytopenia syndrome virus on the disease lethality | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Article
Outbreak of central nervous system infections among children in Thai Binh, Viet Nam
Duc Long Phi, Xuan Duong Tran, Minh Manh To, Hai Yen Dang, Thi Dung Pham, Thi Thu Trang Vu, Trong Kiem Tran, Manh Dung Do, Thi Thuy Vu, Stéphane Ranque, Laetitia Ninove, Sylvie Pillet, Philippe Colson, Bernard La Scola, Van Thuan Hoang & Philippe Gautret
Pages: 1683-1692
Published online: 20 Jun 2022
AbstractforOutbreak of central nervous system infections among children in Thai Binh, Viet Nam | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 2398 Views
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Influenza infections

Article
Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China
Pengfei Cui, Jianzhong Shi, Congcong Wang, Yuancheng Zhang, Xin Xing, Huihui Kong, Cheng Yan, Xianying Zeng, Liling Liu, Guobin Tian, Chengjun Li, Guohua Deng & Hualan Chen
Pages: 1693-1704
Published online: 28 Jun 2022
AbstractforGlobal dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 8412 Views
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Letter

Letter
AIRE gene mutation predisposing chronic mucocutaneous candidiasis and pigmented retinitis in two kids from a Chinese family
Yubo Ma, Xiaowen Wang & Ruoyu Li
Pages: 1705-1706
Published online: 28 Jun 2022
CitationforAIRE gene mutation predisposing chronic mucocutaneous candidiasis and pigmented retinitis in two kids from a Chinese family | Full Text | References | PDF (594.7 KB) | EPUB
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Coronaviruses

Letter
Absence of SARS-CoV-2 in a captive white-tailed deer population in Alabama, USA
Subarna Barua, Chad H. Newbolt, Stephen S. Ditchkoff, Calvin Johnson, Sarah Zohdy, Rachel Smith & Chengming Wang
Pages: 1707-1710
Published online: 28 Jun 2022
First Page PreviewforAbsence of SARS-CoV-2 in a captive white-tailed deer population in Alabama, USA | Full Text | References | PDF (550.5 KB) | EPUB
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Article Commentary
Lessons learned from the COVID-19 control strategy of the XXXII Tokyo Summer Olympics and the XXIV Beijing Winter Olympics
Yi Zhang, Jingwen Ai, Jing Bao & Wenhong Zhang
Pages: 1711-1716
Published online: 04 Jul 2022
AbstractforLessons learned from the COVID-19 control strategy of the XXXII Tokyo Summer Olympics and the XXIV Beijing Winter Olympics | Full Text | References | PDF (705.8 KB) | EPUB
  • 2039 Views
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Article
Modulation of viral replication, apoptosis and antiviral response by induction and mutual regulation of EGR and AP-1 family genes during coronavirus infection
Lixia Yuan, To Sing Fung, Jiawen He, Rui Ai Chen & Ding Xiang Liu
Pages: 1717-1729
Published online: 04 Jul 2022
AbstractforModulation of viral replication, apoptosis and antiviral response by induction and mutual regulation of EGR and AP-1 family genes during coronavirus infection | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2064 Views
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Antimicrobial Agents

Article
Epidemiological and genetic characteristics of clinical carbapenem-resistant Acinetobacter baumannii strains collected countrywide from hospital intensive care units (ICUs) in China
Congcong Liu, Kaichao Chen, Yuchen Wu, Ling Huang, Yinfei Fang, Jiayue Lu, Yu Zeng, Miaomiao Xie, Edward Wai Chi Chan, Sheng Chen & Rong Zhang
Pages: 1730-1741
Published online: 04 Jul 2022
AbstractforEpidemiological and genetic characteristics of clinical carbapenem-resistant Acinetobacter baumannii strains collected countrywide from hospital intensive care units (ICUs) in China | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 4367 Views
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Coronaviruses

Article
Severity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections
Winnie W.Y. Tso, Mike Y.W. Kwan, Yu Liang Wang, Lok Kan Leung, Daniel Leung, Gilbert T. Chua, Patrick Ip, Daniel Y.T. Fong, Wilfred H.S. Wong, Sophelia H.S. Chan, Jasper F.W. Chan, Malik Peiris, Yu Lung Lau & Jaime S. Rosa Duque
Pages: 1742-1750
Published online: 04 Jul 2022
AbstractforSeverity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 8270 Views
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Letter
Head-to-head comparisons of the neutralizing antibody against SARS-CoV-2 variants elicited by four priming-boosting regimens
Hu-Dachuan Jiang, Xi-ling Guo, Peng-Fei Jin, Rong Tang, Jing-Xin Li & Feng-Cai Zhu
Pages: 1751-1753
Published online: 17 Jul 2022
First Page PreviewforHead-to-head comparisons of the neutralizing antibody against SARS-CoV-2 variants elicited by four priming-boosting regimens | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Hepatitis

Article
Molecular epidemiology and genotype-specific disease severity of hepatitis E virus infections in Germany, 2010–2019
Mathias Schemmerer, Jürgen J. Wenzel, Klaus Stark & Mirko Faber
Pages: 1754-1763
Published online: 17 Jul 2022
AbstractforMolecular epidemiology and genotype-specific disease severity of hepatitis E virus infections in Germany, 2010–2019 | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Letter

Letter
Detection of Bartonella vinsonii subsp. berkhoffii in an HIV patient using metagenomic Next-Generation Sequencing
Yuru Shi, Jing Yang, Yingjie Qi, Junlan Xu, Yingqi Shi, Tiantian Shi, Chao Liu & Xiaoling Ma
Pages: 1764-1767
Published online: 17 Jul 2022
AbstractforDetection of Bartonella vinsonii subsp. berkhoffii in an HIV patient using metagenomic Next-Generation Sequencing | Full Text | References | PDF (990.9 KB) | EPUB
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Review

Review
Monkeypox virus emerges from the shadow of its more infamous cousin: family biology matters
Yan Xiang & Addison White
Pages: 1768-1777
Published online: 12 Jul 2022
AbstractforMonkeypox virus emerges from the shadow of its more infamous cousin: family biology matters | Full Text | References | PDF (883.1 KB) | EPUB
  • 13123 Views
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Coronaviruses

Article
Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters
Melanie Rissmann, Danny Noack, Debby van Riel, Katharina S. Schmitz, Rory D. de Vries, Peter van Run, Mart M. Lamers, Corine H. Geurts van Kessel, Marion P. G. Koopmans, Ron A. M. Fouchier, Thijs Kuiken, Bart L. Haagmans & Barry Rockx
Pages: 1778-1786
Published online: 17 Jul 2022
AbstractforPulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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Article Commentary

Article Commentary
Mysterious cases of acute hepatitis in children: is adenovirus still a lead suspect?
Adriana E. Kajon & Kirsten St. George
Pages: 1787-1789
Published online: 17 Jul 2022
First Page PreviewforMysterious cases of acute hepatitis in children: is adenovirus still a lead suspect? | Full Text | References | PDF (426.1 KB) | EPUB
  • 1696 Views
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Tuberculosis

Article
Adjunctive Zoledronate + IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosis1
Hongbo Shen, Enzhuo Yang, Ming Guo, Rui Yang, Guixian Huang, Ying Peng, Wei Sha, Feifei Wang & Ling Shen
Pages: 1790-1805
Published online: 21 Jul 2022
AbstractforAdjunctive Zoledronate + IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosis1 | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1689 Views
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Article
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress
Haoran Wang, Jiao Yao, Yulan Chen, Yuanzhi Wang, Yiduo Liu, Yi Liao, Zhengmin Liang, Yu hui Dong, Mengjin Qu, Xin Ge & Xiangmei Zhou
Pages: 1806-1818
Published online: 21 Jul 2022
AbstractforGut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2381 Views
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Coronaviruses

Article
SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron
Yuanmei Zhu, Xiaojing Dong, Nian Liu, Tong Wu, Huihui Chong, Xiaobo Lei, Lili Ren, Jianwei Wang & Yuxian He
Pages: 1819-1827
Published online: 21 Jul 2022
AbstractforSARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron | Full Text | References | PDF (2 MB) | EPUB
  • 2876 Views
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Article
Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA.1 infection
Chaitanya Kurhade, Jing Zou, Hongjie Xia, Mingru Liu, Qi Yang, Mark Cutler, David Cooper, Alexander Muik, Ugur Sahin, Kathrin U. Jansen, Ping Ren, Xuping Xie, Kena A. Swanson & Pei-Yong Shi
Pages: 1828-1832
Published online: 27 Jul 2022
AbstractforNeutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA.1 infection | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Effect of oral antiseptics in reducing SARS-CoV-2 infectivity: evidence from a randomized double-blind clinical trial
Álvaro Sánchez Barrueco, María Victoria Mateos-Moreno, Yolanda Martínez-Beneyto, Elisa García-Vázquez, Alfonso Campos González, Javier Zapardiel Ferrero, Abel Bogoya Castaño, Ignacio Alcalá Rueda, José Miguel Villacampa Aubá, Carlos Cenjor Español, Laura Moreno-Parrado, Verónica Ausina-Márquez, Sandra García-Esteban, Alejandro Artacho, F. Xavier López-Labrador, Alex Mira & María D. Ferrer
Pages: 1833-1842
Published online: 27 Jul 2022
AbstractforEffect of oral antiseptics in reducing SARS-CoV-2 infectivity: evidence from a randomized double-blind clinical trial | Full Text | References | PDF (2.3 MB) | EPUB
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Research Article

Article
Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease
Jessica Rauch, Johanna Friederike Steffen, Birgit Muntau, Jana Gisbrecht, Kirsten Pörtner, Christiane Herden, Hans Helmut Niller, Markus Bauswein, Dennis Rubbenstroth, Ute Mehlhoop, Petra Allartz & Dennis Tappe
Pages: 1843-1856
Published online: 27 Jul 2022
AbstractforHuman Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2490 Views
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Tuberculosis

Article
High clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates
Kanwara Trisakul, Ditthawat Nonghanphithak, Pratchakan Chaiyachat, Orawee Kaewprasert, Kankanon Sakmongkoljit, Wipa Reechaipichitkul, Angkana Chaiprasert, David Blair, Taane G. Clark & Kiatichai Faksri
Pages: 1857-1866
Published online: 27 Jul 2022
AbstractforHigh clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Research Article

Article
The first invasive Candida auris infection in Taiwan
Yu-Te Tsai, Po-Liang Lu, Hung-Jen Tang, Chung-Hao Huang, Wei-Chun Hung, Yi-Ting Tseng, Kun-Mu Lee & Shang-Yi Lin
Pages: 1867-1875
Published online: 27 Jul 2022
AbstractforThe first invasive Candida auris infection in Taiwan | Full Text | References | PDF (2.4 MB) | EPUB
  • 2240 Views
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Hepatitis

Article
Intrahepatic transcriptomics reveals gene signatures in chronic hepatitis B patients responded to interferon therapy
Ning Li, Kangkang Yu, Minhui Dong, Jinyu Wang, Feifei Yang, Haoxiang Zhu, Jie Yu, Jingshu Yang, Wentao Xie, Bidisha Mitra, Richeng Mao, Feizhen Wu, Haitao Guo & Jiming Zhang
Pages: 1876-1889
Published online: 27 Jul 2022
AbstractforIntrahepatic transcriptomics reveals gene signatures in chronic hepatitis B patients responded to interferon therapy | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 3042 Views
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Coronaviruses

Article
Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice
Xingxing Li, Ling Wang, Jingjing Liu, Enyue Fang, Xiaohui Liu, Qinhua Peng, Zelun Zhang, Miao Li, Xinyu Liu, Xiaohong Wu, Danhua Zhao, Lihong Yang, Jia Li, Shouchun Cao, Yanqiu Huang, Leitai Shi, Hongshan Xu, Yunpeng Wang, Yue Suo, Guangzhi Yue, Jianhui Nie, Weijin Huang, Wenjuan Li & Yuhua Li
Pages: 1890-1899
Published online: 27 Jul 2022
AbstractforCombining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Research Article

Article
Induction of amphotericin B resistance in susceptible Candida auris by extracellular vesicles
Walton Chan, Franklin Wang-Ngai Chow, Chi-Ching Tsang, Xueyan Liu, Weiming Yao, Tony Tat-Yin Chan, Gilman Kit-Hang Siu, Alex Yat-Man Ho, Kristine Shik Luk, Susanna Kar-Pui Lau & Patrick Chiu-Yat Woo
Pages: 1900-1909
Published online: 27 Jul 2022
AbstractforInduction of amphotericin B resistance in susceptible Candida auris by extracellular vesicles | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 4067 Views
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Coronaviruses

Article
Efficacy of heterologous boosting against SARS-CoV-2 using a recombinant interferon-armed fusion protein vaccine (V-01): a randomized, double-blind and placebo-controlled phase III trial
Xuan-Yi Wang, Syed Faisal Mahmood, Fang Jin, Wee Kooi Cheah, Muhammad Ahmad, Mian Amjad Sohail, Waheed Ahmad, Vijaya K. Suppan, Muneeba Ahsan Sayeed, Shobha Luxmi, Aik-Howe Teo, Li Yuan Lee, Yang-Yang Qi, Rong-Juan Pei, Wei Deng, Zhong-Hui Xu, Jia-Ming Yang, Yan Zhang, Wu-Xiang Guan & Xiong Yu
Pages: 1910-1919
Published online: 01 Aug 2022
AbstractforEfficacy of heterologous boosting against SARS-CoV-2 using a recombinant interferon-armed fusion protein vaccine (V-01): a randomized, double-blind and placebo-controlled phase III trial | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Article
An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry
Xi Lin, Liyan Guo, Sheng Lin, Zimin Chen, Fanli Yang, Jing Yang, Lingling Wang, Ao Wen, Yanping Duan, Xindan Zhang, Yushan Dai, Keqing Yin, Xin Yuan, Chongzhang Yu, Bin He, Yu Cao, Haohao Dong, Jian Li, Qi Zhao & Guangwen Lu
Pages: 1920-1935
Published online: 05 Aug 2022
AbstractforAn engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2710 Views
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Antimicrobial Agents

Article
Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns
Dongxing Tian, Xiao Liu, Wenjie Chen, Ying Zhou, Dakang Hu, Weiwen Wang, Jinzuan Wu, Qing Mu & Xiaofei Jiang
Pages: 1936-1949
Published online: 05 Aug 2022
AbstractforPrevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 4596 Views
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Coronaviruses

Article
A case–case study on the effect of primary and booster immunization with China-produced COVID-19 vaccines on prevention of pneumonia and viral load among vaccinated persons infected by Delta and Omicron variants
Dan Wu, Ying Ye, Lin Tang, Ai-Bin Wang, Rui Zhang, Zhao-Hui Qian, Fu-Zhen Wang, Hui Zheng, Chang Huang, Xiao-Ya Lv, Hai-Feng Wang, Yan-Yang Zhang, Jing-Jing Pan, Ya-Fei Li, Ming-Xia Lu, Chang-Shuang Wang, Ya-Ting Ma, Zhi-Jie An, Lance Everett Rodewald, Zun-Dong Yin, Xuan-Yi Wang, Zhi-Yin Wu & Yi-Ming Shao
Pages: 1950-1958
Published online: 05 Aug 2022
AbstractforA case–case study on the effect of primary and booster immunization with China-produced COVID-19 vaccines on prevention of pneumonia and viral load among vaccinated persons infected by Delta and Omicron variants | Full Text | References | PDF (1.5 MB) | EPUB
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Antimicrobial Agents

Article
Frequent convergence of mcr-9 and carbapenemase genes in Enterobacter cloacae complex driven by epidemic plasmids and host incompatibility
Tingting Xu, Chun-Xu Xue, Yuxin Chen, Junxi Huang, Weiyuan Wu, Yuemei Lu, Qiuhui Huang, Dandan Chen & Kai Zhou
Pages: 1959-1972
Published online: 05 Aug 2022
AbstractforFrequent convergence of mcr-9 and carbapenemase genes in Enterobacter cloacae complex driven by epidemic plasmids and host incompatibility | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2179 Views
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Tuberculosis

Article
Mycobacterium paragordonae is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes
Yuanchun Li, Wenping Zhang, Jing Zhao, Wenjie Lai, Yanlin Zhao, Yanming Li & Jiuxin Qu
Pages: 1973-1981
Published online: 08 Aug 2022
AbstractforMycobacterium paragordonae is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 2652 Views
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Research Article

Article
Low-toxin Clostridioides difficile RT027 strains exhibit robust virulence
Farhan Anwar, Bryan Angelo P. Roxas, Kareem W. Shehab, Neil M. Ampel, V. K. Viswanathan & Gayatri Vedantam
Pages: 1982-1993
Published online: 08 Aug 2022
AbstractforLow-toxin Clostridioides difficile RT027 strains exhibit robust virulence | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Article
Development and evaluation of an inactivated coxsackievirus A16 vaccine in gerbils
Yi-Sheng Sun, Yong Xia, Fang Xu, Hang-Jing Lu, Zi-An Mao, Meng Gao, Tian-Yuan Pan, Ping-Ping Yao, Zhen Wang & Han-Ping Zhu
Pages: 1994-2006
Published online: 11 Aug 2022
AbstractforDevelopment and evaluation of an inactivated coxsackievirus A16 vaccine in gerbils | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1740 Views
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Coronaviruses

Article
Comparative global B cell receptor repertoire difference induced by SARS-CoV-2 infection or vaccination via single-cell V(D)J sequencing
Bing He, Shuning Liu, Mengxin Xu, Yunqi Hu, Kexin Lv, Yuanyuan Wang, Yong Ma, Yanmei Zhai, Xinyu Yue, Lin Liu, Hongjie Lu, Siwei Zhou, Pengbin Li, Guoqin Mai, Xiaoping Huang, Chenhang Li, Shifeng Chen, Shupei Ye, Pingsen Zhao, Yuedong Yang, Xinhua Li, Yusheng Jie, Mang Shi, Jingyi Yang, Yuelong Shu & Yao-Qing Chen
Pages: 2007-2020
Published online: 11 Aug 2022
AbstractforComparative global B cell receptor repertoire difference induced by SARS-CoV-2 infection or vaccination via single-cell V(D)J sequencing | Full Text | References | PDF (4.8 MB) | EPUB | Supplemental
  • 4966 Views
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Review

Review
African swine fever control and prevention: an update on vaccine development
Ana Catarina Urbano & Fernando Ferreira
Pages: 2021-2033
Published online: 25 Aug 2022
AbstractforAfrican swine fever control and prevention: an update on vaccine development | Full Text | References | PDF (2 MB) | EPUB
  • 10574 Views
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Antimicrobial Agents

Article
Ultrasensitive and rapid identification of ESRI developer- and piperacillin/tazobactam-resistant Escherichia coli by the MALDIpiptaz test
Angel Rodríguez Villodres, Lydia Gálvez Benítez, Manuel J. Arroyo, Gema Méndez, Luis Mancera, Andrea Vila Domínguez, José Antonio Lepe Jímenez & Younes Smani
Pages: 2034-2044
Published online: 28 Aug 2022
AbstractforUltrasensitive and rapid identification of ESRI developer- and piperacillin/tazobactam-resistant Escherichia coli by the MALDIpiptaz test | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1684 Views
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Coronaviruses

Article
Geriatric risk and protective factors for serious COVID-19 outcomes among older adults in Shanghai Omicron wave
Guanzhu Lu, Yi Zhang, Haocheng Zhang, Jingwen Ai, Liu He, Xiaoling Yuan, Suxia Bao, Xiaohua Chen, Hongyu Wang, Jianpeng Cai, Sen Wang, Wenhong Zhang & Jie Xu
Pages: 2045-2054
Published online: 31 Aug 2022
AbstractforGeriatric risk and protective factors for serious COVID-19 outcomes among older adults in Shanghai Omicron wave | Full Text | References | PDF (2 MB) | EPUB | Supplemental
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Research Article

Article
Correlation of Moraxella catarrhalis macrolide susceptibility with the ability to adhere and invade human respiratory epithelial cells
Ya-li Liu, Rui Ding, Xin-miao Jia, Jing-jing Huang, Shuying Yu, Hiu Tat Chan, Wei Li, Lei-li Mao, Li Zhang, Xin-yao Zhang, Wei Wu, An-ping Ni & Ying-chun Xu
Pages: 2055-2068
Published online: 31 Aug 2022
AbstractforCorrelation of Moraxella catarrhalis macrolide susceptibility with the ability to adhere and invade human respiratory epithelial cells | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 1762 Views
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Article
Evolutionary and genomic insights into the long-term colonization of Shigella flexneri in animals
Junrong Liang, Zhen Zhu, Ruiting Lan, Jing Meng, Bram Vrancken, Shan Lu, Dong Jin, Jing Yang, Jianping Wang, Tian Qin, Ji Pu, Li Zhang, Kui Dong, Mingchao Xu, Huaiyu Tian, Taijiao Jiang & Jianguo Xu
Pages: 2069-2079
Published online: 31 Aug 2022
AbstractforEvolutionary and genomic insights into the long-term colonization of Shigella flexneri in animals | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2627 Views
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Article
Total RNA sequencing of Phlebotomus chinensis sandflies in China revealed viral, bacterial, and eukaryotic microbes potentially pathogenic to humans
Jing Wang, Qin-yu Gou, Geng-yan Luo, Xin Hou, Guodong Liang & Mang Shi
Pages: 2080-2092
Published online: 31 Aug 2022
AbstractforTotal RNA sequencing of Phlebotomus chinensis sandflies in China revealed viral, bacterial, and eukaryotic microbes potentially pathogenic to humans | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 2479 Views
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Coronaviruses

Article
The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage
Ronghui Liang, Zi-Wei Ye, Chon Phin Ong, Zhenzhi Qin, Yubin Xie, Yilan Fan, Kaiming Tang, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Xiaomeng Yang, Hehe Cao, Kun Wang, Haoran Sun, Bodan Hu, Jian-Piao Cai, Cuiting Luo, Kenn Ka-Heng Chik, Hin Chu, Yi Zheng, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Dong-Yan Jin & Shuofeng Yuan
Pages: 2093-2101
Published online: 31 Aug 2022
AbstractforThe spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
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Tuberculosis

Article
High proportion of tuberculosis transmission among social contacts in rural China: a 12-year prospective population-based genomic epidemiological study
Meng Li, Mingcheng Guo, Ying Peng, Qi Jiang, Lan Xia, Sheng Zhong, Yong Qiu, Xin Su, Shu Zhang, Chongguang Yang, Peierdun Mijiti, Qizhi Mao, Howard Takiff, Fabin Li, Chuang Chen & Qian Gao
Pages: 2102-2111
Published online: 31 Aug 2022
AbstractforHigh proportion of tuberculosis transmission among social contacts in rural China: a 12-year prospective population-based genomic epidemiological study | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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Coronaviruses

Letter
Persistence of SARS-CoV-2 neutralizing antibodies longer than 13 months in naturally infected, captive white-tailed deer (Odocoileus virginianus), Texas
Sarah A. Hamer, Chase Nunez, Christopher M. Roundy, Wendy Tang, Logan Thomas, Jack Richison, Jamie S. Benn, Lisa D. Auckland, Terry Hensley, Walter E. Cook, Alex Pauvolid-Corrêa & Gabriel L. Hamer
Pages: 2112-2115
Published online: 31 Aug 2022
AbstractforPersistence of SARS-CoV-2 neutralizing antibodies longer than 13 months in naturally infected, captive white-tailed deer (Odocoileus virginianus), Texas | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Letter
SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong Kong
Rosana Wing-Shan Poon, Brian Pui-Chun Chan, Wan-Mui Chan, Carol Ho-Yan Fong, Xiaojuan Zhang, Lu Lu, Lin-Lei Chen, Joy-Yan Lam, Vincent Chi-Chung Cheng, Samson S. Y. Wong, Kin-Hang Kok, Kwok-Yung Yuen & Kelvin Kai-Wang To
Pages: 2116-2119
Published online: 05 Sep 2022
AbstractforSARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong Kong | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Identification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein
Aiping Wang, Yuanyuan Tian, Hongliang Liu, Peiyang Ding, Yumei Chen, Chao Liang, Yongkun Du, Dawei Jiang, Xifang Zhu, Jiajia Yin & Gaiping Zhang
Pages: 2120-2131
Published online: 14 Sep 2022
AbstractforIdentification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Research Article

Article
Airway acidification impaired host defense against Pseudomonas aeruginosa infection by promoting type 1 interferon β response
Yang Liu, Ying-Zhou Xie, Yi-Han Shi, Ling Yang, Xiao-Yang Chen, Ling-Wei Wang, Jie-Ming Qu, Dong Weng, Xiao-Jian Wang, Hai-Peng Liu, Bao-Xue Ge & Jin-Fu Xu
Pages: 2132-2146
Published online: 14 Sep 2022
AbstractforAirway acidification impaired host defense against Pseudomonas aeruginosa infection by promoting type 1 interferon β response | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
  • 2671 Views
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Article
Serodiagnosis and therapeutic monitoring of New-World tegumentary leishmaniasis using synthetic type-2 glycoinositolphospholipid-based neoglycoproteins
Sayonara M. Viana, Alba L. Montoya, Augusto M. Carvalho, Brunele S. de Mendonça, Susana Portillo, Janet J. Olivas, Nasim H. Karimi, Igor L. Estevao, Uriel Ortega-Rodriguez, Edgar M. Carvalho, Walderez O. Dutra, Rosa A. Maldonaldo, Katja Michael, Camila I. de Oliveira & Igor C. Almeida
Pages: 2147-2159
Published online: 21 Sep 2022
AbstractforSerodiagnosis and therapeutic monitoring of New-World tegumentary leishmaniasis using synthetic type-2 glycoinositolphospholipid-based neoglycoproteins | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Coronaviruses

Article
3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseases
Sebastian Schloer, Daniel Treuherz, Aileen Faist, Marlous de Witt, Katharina Wunderlich, Rainer Wiewrodt, Karsten Wiebe, Peter Barth, Joo-Hee Wälzlein, Susann Kummer, Anne Balkema-Buschmann, Stephan Ludwig, Linda Brunotte & Ursula Rescher
Pages: 2160-2175
Published online: 21 Sep 2022
Abstractfor3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseases | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 2142 Views
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Article
Furin cleavage is required for swine acute diarrhea syndrome coronavirus spike protein-mediated cell – cell fusion
Jinman Kim, Jaewon Yoon & Jung-Eun Park
Pages: 2176-2183
Published online: 21 Sep 2022
AbstractforFurin cleavage is required for swine acute diarrhea syndrome coronavirus spike protein-mediated cell – cell fusion | Full Text | References | PDF (1.5 MB) | EPUB
  • 1984 Views
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Hepatitis

Article
Role of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection
Xinyi Jiang, Le Chang, Ying Yan, Huimin Ji, Huizhen Sun, Yingzi Xiao, Shi Song, Kaihao Feng, Abudulimutailipu Nuermaimaiti & Lunan Wang
Pages: 2184-2196
Published online: 21 Sep 2022
AbstractforRole of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 1512 Views
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Coronaviruses

Article
Early treatment of Favipiravir in COVID-19 patients without pneumonia: a multicentre, open-labelled, randomized control study
Rujipas Sirijatuphat, Weerawat Manosuthi, Suvimol Niyomnaitham, Andrew Owen, Katherine Kradangna Copeland, Lantharita Charoenpong, Manoch Rattanasompattikul, Surakameth Mahasirimongkol, Nuanjun Wichukchinda & Kulkanya Chokephaibulkit
Pages: 2197-2206
Published online: 21 Sep 2022
AbstractforEarly treatment of Favipiravir in COVID-19 patients without pneumonia: a multicentre, open-labelled, randomized control study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3863 Views
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Letter

Letter
An outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021
Juan Li, Nan Ni, Yanan Cui, Shuai Zong, Xue Yao, Tao Hu, Mengyuan Cao, Yong Zhang, Peiqiang Hou, Michael J. Carr, Weijia Xing, Hong Zhou & Weifeng Shi
Pages: 2207-2210
Published online: 21 Sep 2022
AbstractforAn outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021 | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 1696 Views
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Letter
Detection of Leptospira species in bat cadavers, Czech and Slovak Republics
Veronika Seidlova, Petra Straková, Romana Kejíková, Monika Nemcova, Tomáš Bartonička, Jiří Salát, Lucie Dufková, Silvie Šikutová, Jan Mendel, Clifton McKee, Jan Zukal, Jiri Pikula & Ivo Rudolf
Pages: 2211-2213
Published online: 26 Sep 2022
AbstractforDetection of Leptospira species in bat cadavers, Czech and Slovak Republics | Full Text | References | PDF (949.4 KB) | EPUB | Supplemental
  • 1189 Views
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Influenza infections

Letter
A case of human infection by H3N8 influenza virus
Xin Tan, XiaoTian Yan, Yang Liu, Ying Wu, Ji Yang Liu, Mi Mu, Jie Zhao, XiangYun Wang, Jie Qiong Li, Long Wen, Peng Guo, Zhi Guo Zhou, Xiu Bin Li & Peng Tao Bao
Pages: 2214-2217
Published online: 28 Sep 2022
First Page PreviewforA case of human infection by H3N8 influenza virus | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 2256 Views
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Coronaviruses

Letter
Outbreak of cutaneous leishmaniasis before and during the COVID-19 pandemic in Jahrom, an endemic region in the southwest of Iran
Samaneh Mazaherifar, Kavous Solhjoo & Amir Abdoli
Pages: 2218-2221
Published online: 28 Sep 2022
AbstractforOutbreak of cutaneous leishmaniasis before and during the COVID-19 pandemic in Jahrom, an endemic region in the southwest of Iran | Full Text | References | PDF (785.7 KB) | EPUB
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Article
Association of COVID-19 vaccination before conception with maternal liver function during early pregnancy: a cohort study of 7745 Chinese pregnant women
Yan Zhao, Yongbo Zhao, Mengyuan Li, Yicheng Zhou, Yijun Zhang, Xin Su, Ziyi Zhang & Liping Jin
Pages: 2222-2228
Published online: 26 Sep 2022
AbstractforAssociation of COVID-19 vaccination before conception with maternal liver function during early pregnancy: a cohort study of 7745 Chinese pregnant women | Full Text | References | PDF (840.9 KB) | EPUB | Supplemental
  • 1538 Views
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Article
Immunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primates
Amir I. Tukhvatulin, Ilya V. Gordeychuk, Inna V. Dolzhikova, Alina S. Dzharullaeva, Marina E. Krasina, Ekaterina O. Bayurova, Daria M. Grousova, Anna V. Kovyrshina, Alla S. Kondrashova, Daria V. Avdoshina, Stanislav A. Gulyaev, Tatiana V. Gulyaeva, Andrey V. Moroz, Viktoria V. Illarionova, Ilya D. Zorkov, Anna A. Iliukhina, Artem Y. Shelkov, Andrei G. Botikov, Alina S. Erokhova, Dmitry V. Shcheblyakov, Ilias B. Esmagambetov, Olga V. Zubkova, Elisaveta A. Tokarskaya, Daria M. Savina, Yulia R. Vereveyko, Anastasiya S. Ungur, Boris S. Naroditsky, Aydar A. Ishmukhametov, Denis Y. Logunov & Alexander L. Gintsburg
Pages: 2229-2247
Published online: 26 Sep 2022
AbstractforImmunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primates | Full Text | References | PDF (7.4 MB) | EPUB | Supplemental
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Research Article

Article
A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model
Dong Li, Tiantian Sun, Ling Tao, Wangquan Ji, Peiyu Zhu, Ruonan Liang, Yu Zhang, Shuaiyin Chen, Haiyan Yang, Yuefei Jin & Guangcai Duan
Pages: 2248-2263
Published online: 26 Sep 2022
AbstractforA mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 1845 Views
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Antimicrobial Agents

Article
Determinants of fluconazole resistance and echinocandin tolerance in C. parapsilosis isolates causing a large clonal candidemia outbreak among COVID-19 patients in a Brazilian ICU
Farnaz Daneshnia, João N. de Almeida Júnior, Amir Arastehfar, Lisa Lombardi, Erika Shor, Lis Moreno, Ana Verena Mendes, Maria Goreth Barberino, Danilo Thomaz Yamamoto, Geraldine Butler, David S. Perlin & Arnaldo Lopes Colombo
Pages: 2264-2274
Published online: 27 Sep 2022
AbstractforDeterminants of fluconazole resistance and echinocandin tolerance in C. parapsilosis isolates causing a large clonal candidemia outbreak among COVID-19 patients in a Brazilian ICU | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2899 Views
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Coronaviruses

Article
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2
Bingjie Hu, Jasper Fuk-Woo Chan, Huan Liu, Yuanchen Liu, Yue Chai, Jialu Shi, Huiping Shuai, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Chaemin Yoon, Tianrenzheng Zhu, Jinjin Zhang, Wenjun Li, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Bao-Zhong Zhang, Kwok-Yung Yuen & Hin Chu
Pages: 2275-2287
Published online: 28 Sep 2022
AbstractforSpike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2 | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Antimicrobial Agents

Article Commentary
Authors reply: comments on the published meta-analysis of antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries
Olaniyi Ayobami, Simon Brinkwirth, Tim Eckmanns & Robby Markwart
Pages: 2288-2290
Published online: 27 Sep 2022
First Page PreviewforAuthors reply: comments on the published meta-analysis of antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries | Full Text | References | PDF (585.1 KB) | EPUB
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Influenza infections

Article
A variant NS1 protein from H5N2 avian influenza virus suppresses PKR activation and promotes replication and virulence in mammals
Yun-Ting Chung, Chih-Ying Kuan, Guan-Ru Liao, Randy A. Albrecht, Yeu-Yang Tseng, Yu-Chen Hsu, Shan-Chia Ou & Wei-Li Hsu
Pages: 2291-2303
Published online: 09 Oct 2022
AbstractforA variant NS1 protein from H5N2 avian influenza virus suppresses PKR activation and promotes replication and virulence in mammals | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2064 Views
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Coronaviruses

Article
Effectiveness of BNT162b2 and CoronaVac vaccinations against mortality and severe complications after SARS-CoV-2 Omicron BA.2 infection: a case–control study
Vincent Ka Chun Yan, Eric Yuk Fai Wan, Xuxiao Ye, Anna Hoi Ying Mok, Francisco Tsz Tsun Lai, Celine Sze Ling Chui, Xue Li, Carlos King Ho Wong, Philip Hei Li, Tiantian Ma, Simon Qin, Vincent Kai Chung Wong, Tat Chi Tsang, Sik Hon Tsui, William Chun Ming Chui, Benjamin John Cowling, Gabriel Matthew Leung, Chak Sing Lau, Ian Chi Kei Wong & Esther Wai Yin Chan
Pages: 2304-2314
Published online: 09 Oct 2022
AbstractforEffectiveness of BNT162b2 and CoronaVac vaccinations against mortality and severe complications after SARS-CoV-2 Omicron BA.2 infection: a case–control study | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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Article
Preclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Ji-Min Seo, Bobin Kang, Rina Song, Hanmi Noh, Cheolmin Kim, Jong-In Kim, Minsoo Kim, Dong-Kyun Ryu, Min-Ho Lee, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Hansaem Lee, Hye-Min Woo, Jun-Won Kim, Jung-Ah Choi, Manki Song, Monika Tomaszewska-Kiecana, Anna Wołowik, Agnieszka Kulesza, Sunghyun Kim, Keumyoung Ahn, Nahyun Jung & Soo-Young Lee
Pages: 2315-2325
Published online: 27 Sep 2022
AbstractforPreclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
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Research Article

Article
Molecular genetics and epidemiological characteristics of HIV-1 epidemic strains in various sexual risk behaviour groups in developed Eastern China, 2017–2020
Qin Fan, Jiafeng Zhang, Mingyu Luo, Yi Feng, Rui Ge, Yong Yan, Ping Zhong, Xiaobei Ding, Yan Xia, Zhihong Guo, Xiaohong Pan & Chengliang Chai
Pages: 2326-2339
Published online: 27 Sep 2022
AbstractforMolecular genetics and epidemiological characteristics of HIV-1 epidemic strains in various sexual risk behaviour groups in developed Eastern China, 2017–2020 | Full Text | References | PDF (2.9 MB) | EPUB
  • 1836 Views
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Review

Review
Clostridioides difficile spore: coat assembly and formation
Ji Zeng, Hao Wang, Min Dong & Guo-Bao Tian
Pages: 2340-2349
Published online: 29 Sep 2022
AbstractforClostridioides difficile spore: coat assembly and formation | Full Text | References | PDF (1.9 MB) | EPUB
  • 2601 Views
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Zika

Article
Aerosolized Zika virus infection in Guinea pigs
Hong-Ying Qiu, Na-Na Zhang, Qing-Qing Ma, Rui-Ting Li, Meng-Yue Guan, Li-Li Zhang, Jia Zhou, Rong-Rong Zhang, Xing-Yao Huang, Wen-Hui Yang, Yong-Qiang Deng, Cheng-Feng Qin & Dong-Sheng Zhou
Pages: 2350-2358
Published online: 29 Sep 2022
AbstractforAerosolized Zika virus infection in Guinea pigs | Full Text | References | PDF (1.8 MB) | EPUB
  • 1774 Views
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Coronaviruses

Article
A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine
Akihiko Sakamoto, Hiroaki Osawa, Hinata Hashimoto, Tetsushi Mizuno, Ammar A. Hasyim, Yu-ichi Abe, Yuto Okahashi, Ryohei Ogawa, Mitsuhiro Iyori, Hisatoshi Shida & Shigeto Yoshida
Pages: 2359-2370
Published online: 29 Sep 2022
AbstractforA replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1938 Views
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Research Article

Article
Development and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection
Yumin Zhang, Song Liang, Shiyu Zhang, Shidan Zhang, Yong Yu, Huochun Yao, Yongjie Liu, Wei Zhang & Guangjin Liu
Pages: 2371-2382
Published online: 29 Sep 2022
AbstractforDevelopment and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3077 Views
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Coronaviruses

Review
Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern in real-world: a literature review and meta-analysis
Weihao Shao, Xiaorui Chen, Caifang Zheng, Haoshuang Liu, Gaili Wang, Bowen Zhang, Zhiyuan Li & Weidong Zhang
Pages: 2383-2392
Published online: 29 Sep 2022
AbstractforEffectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern in real-world: a literature review and meta-analysis | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 3930 Views
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Review
COVID-19: imbalanced cell-mediated immune response drives to immunopathology
Jun Wang, Qian Li, YuanWang Qiu & Hongzhou Lu
Pages: 2393-2404
Published online: 09 Oct 2022
AbstractforCOVID-19: imbalanced cell-mediated immune response drives to immunopathology | Full Text | References | PDF (2.7 MB) | EPUB
  • 2708 Views
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Research Article

Article
Confirmation of fifth Candida auris clade by whole genome sequencing
Bram Spruijtenburg, Hamid Badali, Mahdi Abastabar, Hossein Mirhendi, Sadegh Khodavaisy, Joobin Sharifisooraki, Mojtaba Taghizadeh Armaki, Theun de Groot & Jacques F. Meis
Pages: 2405-2411
Published online: 18 Oct 2022
AbstractforConfirmation of fifth Candida auris clade by whole genome sequencing | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 4895 Views
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Coronaviruses

Review
Structure-based neutralizing mechanisms for SARS-CoV-2 antibodies
Qingrui Huang, Xiaonan Han & Jinghua Yan
Pages: 2412-2422
Published online: 09 Oct 2022
AbstractforStructure-based neutralizing mechanisms for SARS-CoV-2 antibodies | Full Text | References | PDF (2.7 MB) | EPUB
  • 2313 Views
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Article
Dynamics of viral shedding during ancestral or Omicron BA.1 SARS-CoV-2 infection and enhancement of pre-existing immunity during breakthrough infections
Carla Saade, Karen Brengel-Pesce, Alexandre Gaymard, Mary-Anne Trabaud, Gregory Destras, Guy Oriol, Valérie Cheynet, Marion Debombourg, Bouchra Mokdad, Geneviève Billaud, Antoine Oblette, Hervé Créhalet, Jean-Marc Giannoli, Christine Garrigou, Laurence Generenaz, Christelle Compagnon, André Boibieux, Bruno Lina, Florence Morfin, Bruno Pozzetto, Laurence Josset, Sophie Trouillet Assant & Antonin Bal
Pages: 2423-2432
Published online: 26 Oct 2022
AbstractforDynamics of viral shedding during ancestral or Omicron BA.1 SARS-CoV-2 infection and enhancement of pre-existing immunity during breakthrough infections | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 1980 Views
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Letter

Letter
Cat scratch disease with generalized bone lesions in an immunocompetent child
Jing Wang, Wenjuan Chen, Meng Wang, Qiang Mi, Lijun Bo, Congli Yuan & Qing Cao
Pages: 2433-2436
Published online: 26 Oct 2022
AbstractforCat scratch disease with generalized bone lesions in an immunocompetent child | Full Text | References | PDF (1 MB) | EPUB
  • 1824 Views
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Influenza infections

Article
Clinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus
Libing Zhang, Kaituo Liu, Qin Su, Xiao Chen, Xiaoquan Wang, Qingfeng Li, Wenlei Wang, Xuhua Mao, Jinmei Xu, Xin Zhou, Qin Xu, Le Zhou, Xiufan Liu & Pinghu Zhang
Pages: 2437-2446
Published online: 26 Oct 2022
AbstractforClinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3035 Views
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Zika

Article
Influence of Zika virus 3′-end sequence and nonstructural protein evolution on the viral replication competence and virulence
Hae-Gwang Jung, Hee Cho, Minwoo Kim, Haewon Jung, Yeonju Bak, Se-Young Lee, Han Young Seo, Yu-Min Son, Hawon Woo, Gone Yoon, Seong-Jun Kim & Jong-Won Oh
Pages: 2447-2465
Published online: 26 Oct 2022
AbstractforInfluence of Zika virus 3′-end sequence and nonstructural protein evolution on the viral replication competence and virulence | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
  • 2036 Views
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Coronaviruses

Article
Medium-term outcomes of myocarditis and pericarditis following BNT162b2 vaccination among adolescents in Hong Kong
Gilbert T. Chua, Sabrina Tsao, Mike Yat Wah Kwan, Tak Ching Yu, Agnes Sze Yin Leung, Ka Wah Li, Calvin Chit Kwong Chow, Wai Hung Ku, Janette Kwok, Kelvin K. W. To, Yu Lung Lau, Francisco Tsz Tsun Lai, Ian Chi Kei Wong & Patrick Ip
Pages: 2466-2473
Published online: 26 Oct 2022
AbstractforMedium-term outcomes of myocarditis and pericarditis following BNT162b2 vaccination among adolescents in Hong Kong | Full Text | References | PDF (1.4 MB) | EPUB
  • 1672 Views
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Article
Comparable antigen-specific T cell responses in vaccinees with diverse humoral immune responses after the primary and booster BBIBP-CorV vaccination
Dong Wei, Yingying Chen, Xiaoqi Yu, Yang-dian Lai, Wenxin Xu, Ping Ji, Zhitao Yang, Erzhen Chen, Xinxin Zhang & Ying Wang
Pages: 2474-2484
Published online: 26 Oct 2022
AbstractforComparable antigen-specific T cell responses in vaccinees with diverse humoral immune responses after the primary and booster BBIBP-CorV vaccination | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 2175 Views
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Hepatitis

Article
Compartmentalisation of Hepatitis B virus X gene evolution in hepatocellular carcinoma microenvironment and the genotype-phenotype correlation of tumorigenicity in HBV-related patients with hepatocellular carcinoma
Ya Fu, Fengling Fang, Hongyan Guo, Xialin Xiao, Yuhai Hu, Yongbin Zeng, Tianbin Chen, Songhang Wu, Ni Lin, Jinlan Huang, Ling Jiang, Qishui Ou & Can Liu
Pages: 2485-2500
Published online: 26 Oct 2022
AbstractforCompartmentalisation of Hepatitis B virus X gene evolution in hepatocellular carcinoma microenvironment and the genotype-phenotype correlation of tumorigenicity in HBV-related patients with hepatocellular carcinoma | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1841 Views
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Coronaviruses

Article
Identification of CKD, bedridden history and cancer as higher-risk comorbidities and their impact on prognosis of hospitalized Omicron patients: a multi-centre cohort study
Xiaohua Chen, Hongyu Wang, Jingwen Ai, Leer Shen, Ke Lin, Guanmin Yuan, Xiaohua Sheng, Xia Jin, Zhifeng Deng, Jie Xu, Guanzhu Lu, Shunjie Chen, Jianpeng Cai, Yi Zhang, Haocheng Zhang, Sen Wang, Wenhong Zhang & Cunyi Fan
Pages: 2501-2509
Published online: 26 Oct 2022
AbstractforIdentification of CKD, bedridden history and cancer as higher-risk comorbidities and their impact on prognosis of hospitalized Omicron patients: a multi-centre cohort study | Full Text | References | PDF (1.4 MB) | EPUB
  • 2518 Views
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Enterovirus 71 (EV71)

Article
Molecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study
Xiaoxia Duan, Chaoyong Zhang, Xiao Wang, Xueling Ren, Hongxia Peng, Xueqin Tang, Liangzhi Zhang, Zhenhua Chen, Yan Ye, Mengmou Zheng, Wanzhen Zhong, Xiyue Chen, Yilan Zeng, Ping Yuan & Lu Long
Pages: 2510-2519
Published online: 26 Oct 2022
AbstractforMolecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1826 Views
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Coronaviruses

Review
Consideration of COVID-19 beyond the human-centred approach of prevention and control: the ONE-HEALTH perspective
Qin Li, Robert Bergquist, Liz Grant, Jun-Xia Song, Xin-Yu Feng & Xiao-Nong Zhou
Pages: 2520-2528
Published online: 26 Oct 2022
AbstractforConsideration of COVID-19 beyond the human-centred approach of prevention and control: the ONE-HEALTH perspective | Full Text | References | PDF (1.7 MB) | EPUB
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Article
MERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes
Yujie Feng, Zhaoyi Pan, Zhihui Wang, Zhengyang Lei, Songge Yang, Huajun Zhao, Xueyao Wang, Yating Yu, Qiuju Han & Jian Zhang
Pages: 2529-2543
Published online: 26 Oct 2022
AbstractforMERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
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Research Article

Article
Outbreak of occupational Brucella infection caused by live attenuated Brucella vaccine in a biological products company in Chongqing, China, 2020
Chunbei Zhou, Wenli Huang, Xu Xiang, Jianping Qiu, Dayong Xiao, Ning Yao, Qiang Shu & Shuang Zhou
Pages: 2544-2552
Published online: 26 Oct 2022
AbstractforOutbreak of occupational Brucella infection caused by live attenuated Brucella vaccine in a biological products company in Chongqing, China, 2020 | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 1410 Views
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Letter

Letter
Emergence of chicken infection with novel reassortant H3N8 avian influenza viruses genetically close to human H3N8 isolate, China
Zhimin Wan, Wenjie Jiang, Jianxi Gong, Zhehong Zhao, Ting Tang, Yafeng Li, Jianjun Zhang, Quan Xie, Tuofan Li, Hongxia Shao, Jinhua Liu, Aijian Qin & Jianqiang Ye
Pages: 2553-2555
Published online: 26 Oct 2022
First Page PreviewforEmergence of chicken infection with novel reassortant H3N8 avian influenza viruses genetically close to human H3N8 isolate, China | Full Text | References | PDF (717.6 KB) | EPUB
  • 2015 Views
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Antimicrobial Agents

Article
Interactions between host epithelial cells and Acinetobacter baumannii promote the emergence of highly antibiotic resistant and highly mucoid strains
Wang Zhang, Yue Yao, Hua Zhou, Jintao He, Jingfen Wang, Li Li, Minsong Gao, Xiaochen Liu, Ya Shi, Jinzhong Lin, Jianzhao Liu, Huan Chen, Yu Feng, Zhihui Zhou, Yunsong Yu & Xiaoting Hua
Pages: 2556-2569
Published online: 26 Oct 2022
AbstractforInteractions between host epithelial cells and Acinetobacter baumannii promote the emergence of highly antibiotic resistant and highly mucoid strains | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2454 Views
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Research Article

Article
A One Health view of the West Nile virus outbreak in Andalusia (Spain) in 2020
Jordi Figuerola, Miguel Ángel Jiménez-Clavero, María José Ruíz-López, Francisco Llorente, Santiago Ruiz, Andreas Hoefer, Pilar Aguilera-Sepúlveda, Jéssica Jiménez-Peñuela, Olaya García-Ruiz, Laura Herrero, Ramón C. Soriguer, Raúl Fernández Delgado, María Paz Sánchez-Seco, Josué Martínez-de la Puente & Ana Vázquez
Pages: 2570-2578
Published online: 26 Oct 2022
AbstractforA One Health view of the West Nile virus outbreak in Andalusia (Spain) in 2020 | Full Text | References | PDF (1.4 MB) | EPUB
  • 3217 Views
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Review

Review
Clinical microbiology in detection and identification of emerging microbial pathogens: past, present and future
Hui Wang, Wenhong Zhang & Yi-Wei Tang
Pages: 2579-2589
Published online: 04 Nov 2022
AbstractforClinical microbiology in detection and identification of emerging microbial pathogens: past, present and future | Full Text | References | PDF (1.4 MB) | EPUB
  • 5724 Views
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Research Article

Article
Population genomics of emerging Elizabethkingia anophelis pathogens reveals potential outbreak and rapid global dissemination
Shaohua Hu, Hao Xu, Xiaohua Meng, Xiangxiang Bai, Junli Xu, Jinru Ji, Chaoqun Ying, Yunbo Chen, Ping Shen, Yunxiao Zhou, Beiwen Zheng & Yonghong Xiao
Pages: 2590-2599
Published online: 04 Nov 2022
AbstractforPopulation genomics of emerging Elizabethkingia anophelis pathogens reveals potential outbreak and rapid global dissemination | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 1801 Views
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Review

Review
Comprehensive literature review of monkeypox
Ma’mon M. Hatmal, Mohammad A. I. Al-Hatamleh, Amin N. Olaimat, Suhana Ahmad, Hanan Hasan, Nurfatihah Azlyna Ahmad Suhaimi, Khaled A. Albakri, Anas Abedalbaset Alzyoud, Ramlah Kadir & Rohimah Mohamud
Pages: 2600-2631
Published online: 04 Nov 2022
AbstractforComprehensive literature review of monkeypox | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 7839 Views
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Letter

Letter
Molecular detection and identification of relapsing fever Borrelia in ticks and wild small mammals in China
Xiao-Ai Zhang, Feng Tian, Yue Li, Xiao-Long Zhang, Bao-Gui Jiang, Bao-Cheng Liu, Jing-Tao Zhang, Shen Tian, Heng Ding, Shuang Li, Hao Li, Li-Qun Fang & Wei Liu
Pages: 2632-2635
Published online: 04 Nov 2022
AbstractforMolecular detection and identification of relapsing fever Borrelia in ticks and wild small mammals in China | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1268 Views
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Coronaviruses

Article
Omicron infections profile and vaccination status among 1881 liver transplant recipients: a multi-centre retrospective cohort
Ensi Ma, Jingwen Ai, Yi Zhang, Jianming Zheng, Xiaogang Gao, Junming Xu, Hao Yin, Zhiren Fu, Hao Xing, Li Li, Liying Sun, Heyu Huang, Quanbao Zhang, Linlin Xu, Yanting Jin, Rui Chen, Guoyue Lv, Zhijun Zhu, Wenhong Zhang & Zhengxin Wang
Pages: 2636-2644
Published online: 04 Nov 2022
AbstractforOmicron infections profile and vaccination status among 1881 liver transplant recipients: a multi-centre retrospective cohort | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2671 Views
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Research Article

Article
Oropouche virus as an emerging cause of acute febrile illness in Colombia
Karl A. Ciuoderis, Michael G. Berg, Lester J. Perez, Abbas Hadji, Laura S. Perez-Restrepo, Leidi Carvajal Aristizabal, Kenn Forberg, Julie Yamaguchi, Andres Cardona, Sonja Weiss, Xiaoxing Qiu, Juan Pablo Hernandez-Ortiz, Francisco Averhoff, Gavin A. Cloherty & Jorge E. Osorio
Pages: 2645-2657
Published online: 08 Dec 2022
AbstractforOropouche virus as an emerging cause of acute febrile illness in Colombia | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 4437 Views
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Coronaviruses

Article
Pathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levels
Xiaoxu Zhang, Bixia Hong, Peng Wei, Pengfei Pei, Haifeng Xu, Long Chen, Yigang Tong, Jialin Chen, Shi-Zhong Luo, Huahao Fan & Chengzhi He
Pages: 2658-2669
Published online: 04 Nov 2022
AbstractforPathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levels | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 2251 Views
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Influenza infections

Article
Immunodominance hierarchy after seasonal influenza vaccination
Laura Sánchez-de Prada, Iván Sanz-Muñoz, Raúl Ortiz de Lejarazu, José María Eiros, Adolfo García-Sastre & Teresa Aydillo
Pages: 2670-2679
Published online: 04 Nov 2022
AbstractforImmunodominance hierarchy after seasonal influenza vaccination | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1903 Views
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Coronaviruses

Article
Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study
Dapeng Li, Xuejiao Liao, Zhi Liu, Zhenghua Ma, Jingke Dong, Guoqin Zheng, Mei Zi, Fang Wang, Qing He, Guobao Li, Zheng Zhang & Lei Liu
Pages: 2680-2688
Published online: 04 Nov 2022
AbstractforHealthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 2869 Views
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Article
Heterologous booster with inhaled adenovirus vector COVID-19 vaccine generated more neutralizing antibodies against different SARS-CoV-2 variants
Jiaying Zhong, Shuo Liu, Tingting Cui, Jingxin Li, Fengcai Zhu, Nanshan Zhong, Weijin Huang, Zhuxiang Zhao & Zhongfang Wang
Pages: 2689-2697
Published online: 04 Nov 2022
AbstractforHeterologous booster with inhaled adenovirus vector COVID-19 vaccine generated more neutralizing antibodies against different SARS-CoV-2 variants | Full Text | References | PDF (2.4 MB) | EPUB
  • 6776 Views
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Article
The modulatory action of C-Vx substance on the immune system in COVID-19
Ilhan Tahrali, Nilgun Akdeniz, Vuslat Yilmaz, Umut C. Kucuksezer, Fatma B. Oktelik, Ozkan Ozdemir, Esin Cetin-Aktas, Yelda Ogutmen, Arzu Ergen, Neslihan Abaci, Erdem Tuzun, Oral Oncul & Gunnur Deniz
Pages: 2698-2710
Published online: 04 Nov 2022
AbstractforThe modulatory action of C-Vx substance on the immune system in COVID-19 | Full Text | References | PDF (4.1 MB) | EPUB
  • 1263 Views
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Letter

Letter
Multiple genotypes of Crimean-Congo hemorrhagic fever virus detected in ticks during a one health survey in Agnam, Northeastern Senegal
Moufid Mhamadi, Aminata Badji, Idrissa Dieng, Alioune Gaye, El Hadji Ndiaye, Mignane Ndiaye, Moundhir Mhamadi, Cheikh Talibouya Toure, Aliou Barry, Oumar Ndiaye, Babacar Faye, Fatimata Amadou Ba, Boly Diop, Mamadou Ndiaye, Samba Niang Sagne, Gamou Fall, Cheikh Loucoubar, Hugues Fausther Bovendo, Amadou Alpha Sall, Gary Kobinger, Ousmane Faye, Mawlouth Diallo & Oumar Faye
Pages: 2711-2714
Published online: 09 Nov 2022
AbstractforMultiple genotypes of Crimean-Congo hemorrhagic fever virus detected in ticks during a one health survey in Agnam, Northeastern Senegal | Full Text | References | PDF (801.1 KB) | EPUB
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Research Article

Article
Severe community-acquired pneumonia caused by Chlamydia psittaci genotype E/B strain circulating among geese in Lishui city, Zhejiang province, China
Xin-Cheng Qin, Jinwei Huang, Zhangnv Yang, Xiangrong Sun, Wen Wang, Enhui Gong, Zhuo Cao, Jianfeng Lin, Yanai Qiu, Bohai Wen, Biao Kan, Jianguo Xu & Tian Qin
Pages: 2715-2723
Published online: 10 Nov 2022
AbstractforSevere community-acquired pneumonia caused by Chlamydia psittaci genotype E/B strain circulating among geese in Lishui city, Zhejiang province, China | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1426 Views
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Coronaviruses

Article
A novel RBD-protein/peptide vaccine elicits broadly neutralizing antibodies and protects mice and macaques against SARS-CoV-2
Shixia Wang, Chang Yi Wang, Hui-Kai Kuo, Wen-Jiun Peng, Juin-Hua Huang, Be-Shen Kuo, Feng Lin, Yaw-Jen Liu, Zhi Liu, Huang-Ting Wu, Shuang Ding, Kou-Liang Hou, Jennifer Cheng, Ya-Ting Yang, Ming-Han Jiang, Min-Sheng Wang, Tony Chen, Wei Guo Xia, Ed Lin, Chung Ho Hung, Hui-Jung Chen, Zhonghao Shih, Yi Ling Lin, Valorie Ryan, Mei Mei Hu, D. Gray Heppner, Delphine C. Malherbe, Sivakumar Periasamy, Natalia Kuzmina, Chandru Subramani, Michael Hellerstein, Thomas P. Monath, Alexander Rumyantsev, Alexander Bukreyev & Farshad Guirakhoo
Pages: 2724-2734
Published online: 11 Nov 2022
AbstractforA novel RBD-protein/peptide vaccine elicits broadly neutralizing antibodies and protects mice and macaques against SARS-CoV-2 | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 3488 Views
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Antimicrobial Agents

Article
Emerging and re-emerging KPC-producing hypervirulent Pseudomonas aeruginosa ST697 and ST463 between 2010 and 2021
Biying Zhang, Xun Xu, Xiaomei Song, Yicheng Wen, Zhichen Zhu, Jingnan Lv, Xiaofang Xie, Liang Chen, Yi-Wei Tang & Hong Du
Pages: 2735-2745
Published online: 11 Nov 2022
AbstractforEmerging and re-emerging KPC-producing hypervirulent Pseudomonas aeruginosa ST697 and ST463 between 2010 and 2021 | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Letter

Letter
Novel Rickettsia spp. in two common overwintering North American songbirds
Daniel J. Becker, Allison Byrd, Tara M. Smiley, Mariana Fernandes Marques, Julissa Villegas Nunez, Katherine M. Talbott, Jonathan W. Atwell, Dmitriy V. Volokhov, Ellen D. Ketterson, Alex E. Jahn & Kerry L. Clark
Pages: 2746-2748
Published online: 11 Nov 2022
AbstractforNovel Rickettsia spp. in two common overwintering North American songbirds | Full Text | References | PDF (749.4 KB) | EPUB | Supplemental
  • 1153 Views
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Coronaviruses

Article
Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants
Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong & Ling Chen
Pages: 2749-2761
Published online: 11 Nov 2022
AbstractforShared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 2121 Views
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Review
Risk factors and preventive interventions for post Covid-19 condition: systematic review
Jennifer Pillay, Sholeh Rahman, Samantha Guitard, Aireen Wingert & Lisa Hartling
Pages: 2762-2780
Published online: 11 Nov 2022
AbstractforRisk factors and preventive interventions for post Covid-19 condition: systematic review | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 2476 Views
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Letter

Letter
First identification of human infection with Erysipelothrix Piscisicarius by metagenomic next-generation sequencing
Weifeng Huang, Dan Han, Qingqing Cai, Xiaoli Yi, Jin Tang, Yuan Fang & Yihan Lu
Pages: 2781-2784
Published online: 11 Nov 2022
First Page PreviewforFirst identification of human infection with Erysipelothrix Piscisicarius by metagenomic next-generation sequencing | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Research Article

Article
FBXO34 promotes latent HIV-1 activation by post-transcriptional modulation
Xinyi Yang, Xiaying Zhao, Yuqi Zhu, Jingna Xun, Qin Wen, Hanyu Pan, Jinlong Yang, Jing Wang, Zhimin Liang, Xiaoting Shen, Yue Liang, Qinru Lin, Huitong Liang, Min Li, Jun Chen, Shibo Jiang, Jianqing Xu, Hongzhou Lu & Huanzhang Zhu
Pages: 2785-2799
Published online: 12 Nov 2022
AbstractforFBXO34 promotes latent HIV-1 activation by post-transcriptional modulation | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2367 Views
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Coronaviruses

Article
Estimation of disease burden and clinical severity of COVID-19 caused by Omicron BA.2 in Shanghai, February-June 2022
Xinhua Chen, Xuemei Yan, Kaiyuan Sun, Nan Zheng, Ruijia Sun, Jiaxin Zhou, Xiaowei Deng, Tingyu Zhuang, Jun Cai, Juanjuan Zhang, Marco Ajelli & Hongjie Yu
Pages: 2800-2807
Published online: 21 Nov 2022
AbstractforEstimation of disease burden and clinical severity of COVID-19 caused by Omicron BA.2 in Shanghai, February-June 2022 | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 4647 Views
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