Molecular and Cellular Biology, Volume 18, Issue 7 (1998)

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Molecular and Cellular Biology, Volume 18, Issue 7 (1998)

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Transcriptional Regulation

Article
RB and c-Myc Activate Expression of the E-Cadherin Gene in Epithelial Cells through Interaction with Transcription Factor AP-2
Eric Batsché, Christian Muchardt, Jürgen Behrens, Helen C. Hurst & Chantal Crémisi
Pages: 3647-3658
Published online: 28 Mar 2023
AbstractforRB and c-Myc Activate Expression of the E-Cadherin Gene in Epithelial Cells through Interaction with Transcription Factor AP-2 | Full Text | References | PDF (739.3 KB)
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Article
Role of Histone H1 as an Architectural Determinant of Chromatin Structure and as a Specific Repressor of Transcription onXenopus Oocyte 5S rRNA Genes
Takashi Sera & Alan P. Wolffe
Pages: 3668-3680
Published online: 28 Mar 2023
AbstractforRole of Histone H1 as an Architectural Determinant of Chromatin Structure and as a Specific Repressor of Transcription onXenopus Oocyte 5S rRNA Genes | Full Text | References | PDF (2 MB)
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Article
Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain
Mark W. Frazier, Xiaoping He, JinLing Wang, Zhengming Gu, John L. Cleveland & Gerard P. Zambetti
Pages: 3735-3743
Published online: 28 Mar 2023
AbstractforActivation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain | Full Text | References | PDF (887.8 KB)
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Article
Cyclosporin A-Sensitive Transcription Factor Egr-3 Regulates Fas Ligand Expression
Paul R. Mittelstadt & Jonathan D. Ashwell
Pages: 3744-3751
Published online: 28 Mar 2023
AbstractforCyclosporin A-Sensitive Transcription Factor Egr-3 Regulates Fas Ligand Expression | Full Text | References | PDF (441.8 KB)
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Article
Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo
Joan S. Steffan, Daniel A. Keys, Loan Vu & Masayasu Nomura
Pages: 3752-3761
Published online: 28 Mar 2023
AbstractforInteraction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo | Full Text | References | PDF (1.1 MB)
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Article
Even-skipped Represses Transcription by Binding TATA Binding Protein and Blocking the TFIID-TATA Box Interaction
Chi Li & James L. Manley
Pages: 3771-3781
Published online: 28 Mar 2023
AbstractforEven-skipped Represses Transcription by Binding TATA Binding Protein and Blocking the TFIID-TATA Box Interaction | Full Text | References | PDF (1.3 MB)
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Article
Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors
Yan Luo, Hui Ge, Sean Stevens, Hua Xiao & Robert G. Roeder
Pages: 3803-3810
Published online: 28 Mar 2023
AbstractforCoactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors | Full Text | References | PDF (603.2 KB)
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Article
Xenopus TFIIIA Gene Transcription Is Dependent on cis-Element Positioning and Chromatin Structure
Samuel L. Pfaff & William L. Taylor
Pages: 3811-3818
Published online: 28 Mar 2023
AbstractforXenopus TFIIIA Gene Transcription Is Dependent on cis-Element Positioning and Chromatin Structure | Full Text | References | PDF (598 KB)
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Article
Molecular Mechanism Governing Heme Signaling in Yeast: a Higher-Order Complex Mediates Heme Regulation of the Transcriptional Activator HAP1
Li Zhang, Angela Hach & Cheng Wang
Pages: 3819-3828
Published online: 28 Mar 2023
AbstractforMolecular Mechanism Governing Heme Signaling in Yeast: a Higher-Order Complex Mediates Heme Regulation of the Transcriptional Activator HAP1 | Full Text | References | PDF (946.8 KB)
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Article
TATA Binding Protein Discriminates between Different Lesions on DNA, Resulting in a Transcription Decrease
Frédéric Coin, Philippe Frit, Benoit Viollet, Bernard Salles & Jean-Marc Egly
Pages: 3907-3914
Published online: 28 Mar 2023
AbstractforTATA Binding Protein Discriminates between Different Lesions on DNA, Resulting in a Transcription Decrease | Full Text | References | PDF (1.3 MB)
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Article
Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1
Martha S. Petrovick, Scott W. Hiebert, Alan D. Friedman, Christopher J. Hetherington, Daniel G. Tenen & Dong-Er Zhang
Pages: 3915-3925
Published online: 28 Mar 2023
AbstractforMultiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1 | Full Text | References | PDF (502 KB)
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Article
Simian Virus 40 Large T Antigen Stabilizes the TATA-Binding Protein–TFIIA Complex on the TATA Element
Blossom Damania, Paul Lieberman & James C. Alwine
Pages: 3926-3935
Published online: 28 Mar 2023
AbstractforSimian Virus 40 Large T Antigen Stabilizes the TATA-Binding Protein–TFIIA Complex on the TATA Element | Full Text | References | PDF (2.8 MB)
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Article
Adenovirus E1B 19,000-Molecular-Weight Protein Activates c-Jun N-Terminal Kinase and c-Jun-Mediated Transcription
Raymond H. See & Yang Shi
Pages: 4012-4022
Published online: 28 Mar 2023
AbstractforAdenovirus E1B 19,000-Molecular-Weight Protein Activates c-Jun N-Terminal Kinase and c-Jun-Mediated Transcription | Full Text | References | PDF (915.5 KB)
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Article
DA-Complex Assembly Activity Required for VP16C Transcriptional Activation
Naoko Kobayashi, Peter J. Horn, Susan M. Sullivan, Steven J. Triezenberg, Thomas G. Boyer & Arnold J. Berk
Pages: 4023-4031
Published online: 28 Mar 2023
AbstractforDA-Complex Assembly Activity Required for VP16C Transcriptional Activation | Full Text | References | PDF (1.3 MB)
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Article
Role of the PAS Domain in Regulation of Dimerization and DNA Binding Specificity of the Dioxin Receptor
Ingemar Pongratz, Camilla Antonsson, Murray L. Whitelaw & Lorenz Poellinger
Pages: 4079-4088
Published online: 28 Mar 2023
AbstractforRole of the PAS Domain in Regulation of Dimerization and DNA Binding Specificity of the Dioxin Receptor | Full Text | References | PDF (1.3 MB)
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Article
Regulation of Transcription by Hypoxia Requires a Multiprotein Complex That Includes Hypoxia-Inducible Factor 1, an Adjacent Transcription Factor, and p300/CREB Binding Protein
Benjamin L. Ebert & H. Franklin Bunn
Pages: 4089-4096
Published online: 28 Mar 2023
AbstractforRegulation of Transcription by Hypoxia Requires a Multiprotein Complex That Includes Hypoxia-Inducible Factor 1, an Adjacent Transcription Factor, and p300/CREB Binding Protein | Full Text | References | PDF (866.4 KB)
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Article
The C-Terminal Domain of Sin1 Interacts with the SWI-SNF Complex in Yeast
José Pérez-Martín & Alexander D. Johnson
Pages: 4157-4164
Published online: 28 Mar 2023
AbstractforThe C-Terminal Domain of Sin1 Interacts with the SWI-SNF Complex in Yeast | Full Text | References | PDF (2 MB)
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Article
Two Domains Unique to Osteoblast-Specific Transcription Factor Osf2/Cbfa1 Contribute to Its Transactivation Function and Its Inability To Heterodimerize with Cbfβ
Kannan Thirunavukkarasu, Muktar Mahajan, Keith W. McLarren, Stefano Stifani & Gerard Karsenty
Pages: 4197-4208
Published online: 28 Mar 2023
AbstractforTwo Domains Unique to Osteoblast-Specific Transcription Factor Osf2/Cbfa1 Contribute to Its Transactivation Function and Its Inability To Heterodimerize with Cbfβ | Full Text | References | PDF (1.2 MB)
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Article
The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils
Friedemann Kiefer, John Brumell, Nadia Al-Alawi, Sylvain Latour, Alec Cheng, André Veillette, Sergio Grinstein & Tony Pawson
Pages: 4209-4220
Published online: 28 Mar 2023
AbstractforThe Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils | Full Text | References | PDF (5 MB)
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Article
DNA-Dependent Protein Kinase Phosphorylation of IκBα and IκBβ Regulates NF-κB DNA Binding Properties
Li Liu, Youn-Tae Kwak, Françoise Bex, León F. García-Martínez, Xiao-Hua Li, Katheryn Meek, William S. Lane & Richard B. Gaynor
Pages: 4221-4234
Published online: 28 Mar 2023
AbstractforDNA-Dependent Protein Kinase Phosphorylation of IκBα and IκBβ Regulates NF-κB DNA Binding Properties | Full Text | References | PDF (2.5 MB)
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Article
BAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor
Shinichiro Okabe, Tetsuya Fukuda, Kazuki Ishibashi, Satoko Kojima, Seiji Okada, Masahiko Hatano, Masaaki Ebara, Hiromitsu Saisho & Takeshi Tokuhisa
Pages: 4235-4244
Published online: 28 Mar 2023
AbstractforBAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor | Full Text | References | PDF (1 MB)
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Article
Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation
Yuka Kanno, Tomohiko Kanno, Chohei Sakakura, Suk-Chul Bae & Yoshiaki Ito
Pages: 4252-4261
Published online: 28 Mar 2023
AbstractforCytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation | Full Text | References | PDF (443.5 KB)
  • 19 Views
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Article
Normal Myeloid Development Requires Both the Glutamine-Rich Transactivation Domain and the PEST Region of Transcription Factor PU.1 but Not the Potent Acidic Transactivation Domain
Robert C. Fisher, Marilyn C. Olson, Jagan M. R. Pongubala, Jeffrey M. Perkel, Michael L. Atchison, Edward W. Scott & M. Celeste Simon
Pages: 4347-4357
Published online: 28 Mar 2023
AbstractforNormal Myeloid Development Requires Both the Glutamine-Rich Transactivation Domain and the PEST Region of Transcription Factor PU.1 but Not the Potent Acidic Transactivation Domain | Full Text | References | PDF (1.7 MB)
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Article
Transcriptional Regulation of the MDR1 Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y
Shengkan Jin & Kathleen W. Scotto
Pages: 4377-4384
Published online: 28 Mar 2023
AbstractforTranscriptional Regulation of the MDR1 Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y | Full Text | References | PDF (542.3 KB)
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Cell Growth and Development

Article
Cyclin-Stimulated Binding of Cks Proteins to Cyclin-Dependent Kinases
Elizabeth A. Egan & Mark J. Solomon
Pages: 3659-3667
Published online: 28 Mar 2023
AbstractforCyclin-Stimulated Binding of Cks Proteins to Cyclin-Dependent Kinases | Full Text | References | PDF (763.4 KB)
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Article
Pheromone-Dependent G1 Cell Cycle Arrest Requires Far1 Phosphorylation, but May Not Involve Inhibition of Cdc28-Cln2 Kinase, In Vivo
Anton Gartner, Alexandra Jovanović, Doo-Il Jeoung, Sarah Bourlat, Frederick R. Cross & Gustav Ammerer
Pages: 3681-3691
Published online: 28 Mar 2023
AbstractforPheromone-Dependent G1 Cell Cycle Arrest Requires Far1 Phosphorylation, but May Not Involve Inhibition of Cdc28-Cln2 Kinase, In Vivo | Full Text | References | PDF (1.6 MB)
  • 35 Views
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Article
Characterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest
Kevin M. Ryan & Karen H. Vousden
Pages: 3692-3698
Published online: 28 Mar 2023
AbstractforCharacterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest | Full Text | References | PDF (311.9 KB)
  • 412 Views
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Article
AP1 Regulation of Proliferation and Initiation of Apoptosis in Erythropoietin-Dependent Erythroid Cells
Sarah M. Jacobs-Helber, Amittha Wickrema, Michael J. Birrer & Stephen T. Sawyer
Pages: 3699-3707
Published online: 28 Mar 2023
AbstractforAP1 Regulation of Proliferation and Initiation of Apoptosis in Erythropoietin-Dependent Erythroid Cells | Full Text | References | PDF (1.2 MB)
  • 28 Views
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Article
Requirement for Activation of the Serine-Threonine Kinase Akt (Protein Kinase B) in Insulin Stimulation of Protein Synthesis but Not of Glucose Transport
Tadahiro Kitamura, Wataru Ogawa, Hiroshi Sakaue, Yasuhisa Hino, Shoji Kuroda, Masafumi Takata, Michihiro Matsumoto, Tetsuo Maeda, Hiroaki Konishi, Ushio Kikkawa & Masato Kasuga
Pages: 3708-3717
Published online: 28 Mar 2023
AbstractforRequirement for Activation of the Serine-Threonine Kinase Akt (Protein Kinase B) in Insulin Stimulation of Protein Synthesis but Not of Glucose Transport | Full Text | References | PDF (1.2 MB)
  • 28 Views
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Article
Differential Effects of Protein Kinase A on Ras Effector Pathways
Marsha J. Miller, Lise Rioux, Gregory V. Prendergast, Sarah Cannon, Michael A. White & Judy L. Meinkoth
Pages: 3718-3726
Published online: 28 Mar 2023
AbstractforDifferential Effects of Protein Kinase A on Ras Effector Pathways | Full Text | References | PDF (1.9 MB)
  • 1 Views
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Article
Identification of the Cytoplasmic Regions of Fibroblast Growth Factor (FGF) Receptor 1 Which Play Important Roles in Induction of Neurite Outgrowth in PC12 Cells by FGF-1
Hsien-Yi Lin, Jingsong Xu, Irene Ischenko, David M. Ornitz, Simon Halegoua & Michael J. Hayman
Pages: 3762-3770
Published online: 28 Mar 2023
AbstractforIdentification of the Cytoplasmic Regions of Fibroblast Growth Factor (FGF) Receptor 1 Which Play Important Roles in Induction of Neurite Outgrowth in PC12 Cells by FGF-1 | Full Text | References | PDF (1.4 MB)
  • 13 Views
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Article
Tyrosine Phosphorylation of Cdc2 Is Required for the Replication Checkpoint in Schizosaccharomyces pombe
Nicholas Rhind & Paul Russell
Pages: 3782-3787
Published online: 28 Mar 2023
AbstractforTyrosine Phosphorylation of Cdc2 Is Required for the Replication Checkpoint in Schizosaccharomyces pombe | Full Text | References | PDF (275.4 KB)
  • 12 Views
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Article
Role of Phosphatidylinositol 4,5-Bisphosphate in Ras/Rac-Induced Disruption of the Cortactin-Actomyosin II Complex and Malignant Transformation
Hong He, Takeshi Watanabe, Xi Zhan, Cai Huang, Ed Schuuring, Kiyoko Fukami, Tadaomi Takenawa, C. Chandra Kumar, Richard J. Simpson & Hiroshi Maruta
Pages: 3829-3837
Published online: 28 Mar 2023
AbstractforRole of Phosphatidylinositol 4,5-Bisphosphate in Ras/Rac-Induced Disruption of the Cortactin-Actomyosin II Complex and Malignant Transformation | Full Text | References | PDF (629.7 KB)
  • 11 Views
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Article
Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages
John F. Timms, Kristen Carlberg, Haihua Gu, Haiyan Chen, Shubhangi Kamatkar, Monica J. S. Nadler, Larry R. Rohrschneider & Benjamin G. Neel
Pages: 3838-3850
Published online: 28 Mar 2023
AbstractforIdentification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages | Full Text | References | PDF (2.2 MB)
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Article
Differential Utilization of Ras Signaling Pathways by Macrophage Colony-Stimulating Factor (CSF) and Granulocyte-Macrophage CSF Receptors during Macrophage Differentiation
Fabien Guidez, Andrew C. Li, Andrew Horvai, John S. Welch & Christopher K. Glass
Pages: 3851-3861
Published online: 28 Mar 2023
AbstractforDifferential Utilization of Ras Signaling Pathways by Macrophage Colony-Stimulating Factor (CSF) and Granulocyte-Macrophage CSF Receptors during Macrophage Differentiation | Full Text | References | PDF (1.4 MB)
  • 40 Views
  • 28 CrossRef citations
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Article
Inhibition of Clathrin-Mediated Endocytosis Selectively Attenuates Specific Insulin Receptor Signal Transduction Pathways
Brian P. Ceresa, Aimee W. Kao, Scott R. Santeler & Jeffrey E. Pessin
Pages: 3862-3870
Published online: 28 Mar 2023
AbstractforInhibition of Clathrin-Mediated Endocytosis Selectively Attenuates Specific Insulin Receptor Signal Transduction Pathways | Full Text | References | PDF (525.4 KB)
  • 51 Views
  • 179 CrossRef citations
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Article
Identification and Characterization of a Constitutively Active STAT5 Mutant That Promotes Cell Proliferation
Mayumi Onishi, Tetsuya Nosaka, Kazuhide Misawa, Alice L.-F. Mui, Daniel Gorman, Martin McMahon, Atsushi Miyajima & Toshio Kitamura
Pages: 3871-3879
Published online: 28 Mar 2023
AbstractforIdentification and Characterization of a Constitutively Active STAT5 Mutant That Promotes Cell Proliferation | Full Text | References | PDF (1.1 MB)
  • 154 Views
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Article
Rac Regulates Integrin-Mediated Spreading and Increased Adhesion of T Lymphocytes
Crislyn D’Souza-Schorey, Benjamin Boettner & Linda Van Aelst
Pages: 3936-3946
Published online: 28 Mar 2023
AbstractforRac Regulates Integrin-Mediated Spreading and Increased Adhesion of T Lymphocytes | Full Text | References | PDF (2.3 MB)
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Article
14-3-3 Facilitates Ras-Dependent Raf-1 Activation In Vitro and In Vivo
Sandrine Roy, Robert A. McPherson, Ann Apolloni, Jun Yan, Annette Lane, Jodi Clyde-Smith & John F. Hancock
Pages: 3947-3955
Published online: 28 Mar 2023
Abstractfor14-3-3 Facilitates Ras-Dependent Raf-1 Activation In Vitro and In Vivo | Full Text | References | PDF (703.7 KB)
  • 40 Views
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Article
A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability
Imed-eddine Gallouzi, Fabienne Parker, Karim Chebli, Florence Maurier, Emmanuel Labourier, Isabelle Barlat, Jean-Paul Capony, Bruno Tocque & Jamal Tazi
Pages: 3956-3965
Published online: 28 Mar 2023
AbstractforA Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability | Full Text | References | PDF (1.2 MB)
  • 89 Views
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Article
Binding of Shp2 Tyrosine Phosphatase to FRS2 Is Essential for Fibroblast Growth Factor-Induced PC12 Cell Differentiation
Y. R. Hadari, H. Kouhara, I. Lax & J. Schlessinger
Pages: 3966-3973
Published online: 28 Mar 2023
AbstractforBinding of Shp2 Tyrosine Phosphatase to FRS2 Is Essential for Fibroblast Growth Factor-Induced PC12 Cell Differentiation | Full Text | References | PDF (1.1 MB)
  • 61 Views
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Article
The Mdm2 Oncoprotein Interacts with the Cell Fate Regulator Numb
Tamar Juven-Gershon, Ohad Shifman, Tamar Unger, Adi Elkeles, Ygal Haupt & Moshe Oren
Pages: 3974-3982
Published online: 28 Mar 2023
AbstractforThe Mdm2 Oncoprotein Interacts with the Cell Fate Regulator Numb | Full Text | References | PDF (884.6 KB)
  • 15 Views
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Article
Growth Suppression by an E2F-Binding-Defective Retinoblastoma Protein (RB): Contribution from the RB C Pocket
Laura L. Whitaker, Heyun Su, Rajasekaran Baskaran, Erik S. Knudsen & Jean Y. J. Wang
Pages: 4032-4042
Published online: 28 Mar 2023
AbstractforGrowth Suppression by an E2F-Binding-Defective Retinoblastoma Protein (RB): Contribution from the RB C Pocket | Full Text | References | PDF (423.4 KB)
  • 13 Views
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Article
Myb-Related Schizosaccharomyces pombecdc5p Is Structurally and Functionally Conserved in Eukaryotes
Ryoma Ohi, Anna Feoktistova, Stacey McCann, Virginia Valentine, A. Thomas Look, Joseph S. Lipsick & Kathleen L. Gould
Pages: 4097-4108
Published online: 28 Mar 2023
AbstractforMyb-Related Schizosaccharomyces pombecdc5p Is Structurally and Functionally Conserved in Eukaryotes | Full Text | References | PDF (1.5 MB)
  • 14 Views
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Article
Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase
Mariko Takahashi-Tezuka, Yuichi Yoshida, Toshiyuki Fukada, Takuya Ohtani, Yojiro Yamanaka, Keigo Nishida, Koichi Nakajima, Masahiko Hibi & Toshio Hirano
Pages: 4109-4117
Published online: 28 Mar 2023
AbstractforGab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase | Full Text | References | PDF (1.1 MB)
  • 21 Views
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Article
Tumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor
Jonathan A. Epstein, Baoliang Song, Maha Lakkis & Chiayeng Wang
Pages: 4118-4130
Published online: 28 Mar 2023
AbstractforTumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor | Full Text | References | PDF (1.1 MB)
  • 31 Views
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Article
Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt
Christopher D. Kontos, Thomas P. Stauffer, Wen-Pin Yang, John D. York, Liwen Huang, Michael A. Blanar, Tobias Meyer & Kevin G. Peters
Pages: 4131-4140
Published online: 28 Mar 2023
AbstractforTyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt | Full Text | References | PDF (1.7 MB)
  • 47 Views
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Article
Targeted Disruption of the Gene Encoding Hepatocyte Nuclear Factor 3γ Results in Reduced Transcription of Hepatocyte-Specific Genes
Klaus H. Kaestner, Holger Hiemisch & Günther Schütz
Pages: 4245-4251
Published online: 28 Mar 2023
AbstractforTargeted Disruption of the Gene Encoding Hepatocyte Nuclear Factor 3γ Results in Reduced Transcription of Hepatocyte-Specific Genes | Full Text | References | PDF (1.5 MB)
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Article
Activated Polo-Like Kinase Plx1 Is Required at Multiple Points during Mitosis in Xenopus laevis
Yue-Wei Qian, Eleanor Erikson, Chuan Li & James L. Maller
Pages: 4262-4271
Published online: 28 Mar 2023
AbstractforActivated Polo-Like Kinase Plx1 Is Required at Multiple Points during Mitosis in Xenopus laevis | Full Text | References | PDF (1.5 MB)
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Article
Calcium and S100B Regulation of p53-Dependent Cell Growth Arrest and Apoptosis
Christian Scotto, Jean Christophe Deloulme, Denis Rousseau, Edmond Chambaz & Jacques Baudier
Pages: 4272-4281
Published online: 28 Mar 2023
AbstractforCalcium and S100B Regulation of p53-Dependent Cell Growth Arrest and Apoptosis | Full Text | References | PDF (2.7 MB)
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Article
Involvement of Prolonged Ras Activation in Thrombopoietin-Induced Megakaryocytic Differentiation of a Human Factor-Dependent Hematopoietic Cell Line
Itaru Matsumura, Koichi Nakajima, Hiroshi Wakao, Seisuke Hattori, Koji Hashimoto, Hiroyuki Sugahara, Takashi Kato, Hiroshi Miyazaki, Toshio Hirano & Yuzuru Kanakura
Pages: 4282-4290
Published online: 28 Mar 2023
AbstractforInvolvement of Prolonged Ras Activation in Thrombopoietin-Induced Megakaryocytic Differentiation of a Human Factor-Dependent Hematopoietic Cell Line | Full Text | References | PDF (2.2 MB)
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Article
Human Cyclin K, a Novel RNA Polymerase II-Associated Cyclin Possessing Both Carboxy-Terminal Domain Kinase and Cdk-Activating Kinase Activity
Michael C. Edwards, Calvin Wong & Stephen J. Elledge
Pages: 4291-4300
Published online: 28 Mar 2023
AbstractforHuman Cyclin K, a Novel RNA Polymerase II-Associated Cyclin Possessing Both Carboxy-Terminal Domain Kinase and Cdk-Activating Kinase Activity | Full Text | References | PDF (1.1 MB)
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Article
CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors
Hanna S. Radomska, Claudia S. Huettner, Pu Zhang, Tao Cheng, David T. Scadden & Daniel G. Tenen
Pages: 4301-4314
Published online: 28 Mar 2023
AbstractforCCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors | Full Text | References | PDF (2.3 MB)
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Article
Interactions among Drosophila Nuclear Envelope Proteins Lamin, Otefin, and YA
Michal Goldberg, Huihua Lu, Nico Stuurman, Ruth Ashery-Padan, Aryeh M. Weiss, Jing Yu, Debika Bhattacharyya, Paul A. Fisher, Yosef Gruenbaum & Mariana F. Wolfner
Pages: 4315-4323
Published online: 28 Mar 2023
AbstractforInteractions among Drosophila Nuclear Envelope Proteins Lamin, Otefin, and YA | Full Text | References | PDF (361.8 KB)
  • 30 Views
  • 55 CrossRef citations
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Article
Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− Mice
Yang Xu, Eva Marie Yang, James Brugarolas, Tyler Jacks & David Baltimore
Pages: 4385-4390
Published online: 28 Mar 2023
AbstractforInvolvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− Mice | Full Text | References | PDF (372.1 KB)
  • 21 Views
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Cell and Organelle Structure and Assembly

Article
SBA1 Encodes a Yeast Hsp90 Cochaperone That Is Homologous to Vertebrate p23 Proteins
Yifang Fang, Albert E. Fliss, Jie Rao & Avrom J. Caplan
Pages: 3727-3734
Published online: 28 Mar 2023
AbstractforSBA1 Encodes a Yeast Hsp90 Cochaperone That Is Homologous to Vertebrate p23 Proteins | Full Text | References | PDF (1.6 MB)
  • 18 Views
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Article
Prohibitin Family Members Interact Genetically with Mitochondrial Inheritance Components in Saccharomyces cerevisiae
Karen H. Berger & Michael P. Yaffe
Pages: 4043-4052
Published online: 28 Mar 2023
AbstractforProhibitin Family Members Interact Genetically with Mitochondrial Inheritance Components in Saccharomyces cerevisiae | Full Text | References | PDF (2.5 MB)
  • 17 Views
  • 146 CrossRef citations
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Article
Spa2p Interacts with Cell Polarity Proteins and Signaling Components Involved in Yeast Cell Morphogenesis
Yi-Jun Sheu, Beatriz Santos, Nathalie Fortin, Christine Costigan & Michael Snyder
Pages: 4053-4069
Published online: 28 Mar 2023
AbstractforSpa2p Interacts with Cell Polarity Proteins and Signaling Components Involved in Yeast Cell Morphogenesis | Full Text | References | PDF (2.2 MB)
  • 77 Views
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Article
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
Mikiko C. Siomi, Micheline Fromont, Jean-Christophe Rain, Lili Wan, Fan Wang, Pierre Legrain & Gideon Dreyfuss
Pages: 4141-4148
Published online: 28 Mar 2023
AbstractforFunctional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms | Full Text | References | PDF (1.2 MB)
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Article
PEX12, the Pathogenic Gene of Group III Zellweger Syndrome: cDNA Cloning by Functional Complementation on a CHO Cell Mutant, Patient Analysis, and Characterization of Pex12p
Kanji Okumoto, Nobuyuki Shimozawa, Atsusi Kawai, Shigehiko Tamura, Toshiro Tsukamoto, Takashi Osumi, Hugo Moser, Ronald J. A. Wanders, Yasuyuki Suzuki, Naomi Kondo & Yukio Fujiki
Pages: 4324-4336
Published online: 28 Mar 2023
AbstractforPEX12, the Pathogenic Gene of Group III Zellweger Syndrome: cDNA Cloning by Functional Complementation on a CHO Cell Mutant, Patient Analysis, and Characterization of Pex12p | Full Text | References | PDF (3.3 MB)
  • 40 Views
  • 80 CrossRef citations
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Gene Expression

Article
Mutational Analysis of an RNA Recognition Element That Mediates Localization of bicoid mRNA
Paul M. Macdonald & Karen Kerr
Pages: 3788-3795
Published online: 28 Mar 2023
AbstractforMutational Analysis of an RNA Recognition Element That Mediates Localization of bicoid mRNA | Full Text | References | PDF (552.4 KB)
  • 4 Views
  • 62 CrossRef citations
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Article
Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex
Lorena Navarro, Kerri Mowen, Steven Rodems, Brian Weaver, Nancy Reich, Deborah Spector & Michael David
Pages: 3796-3802
Published online: 28 Mar 2023
AbstractforCytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex | Full Text | References | PDF (944 KB)
  • 38 Views
  • 129 CrossRef citations
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Article
Differential Requirements for Alternative Splicing and Nuclear Export Functions of Equine Infectious Anemia Virus Rev Protein
Matthew E. Harris, Richard R. Gontarek, David Derse & Thomas J. Hope
Pages: 3889-3899
Published online: 28 Mar 2023
AbstractforDifferential Requirements for Alternative Splicing and Nuclear Export Functions of Equine Infectious Anemia Virus Rev Protein | Full Text | References | PDF (2 MB)
  • 8 Views
  • 29 CrossRef citations
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Article
Alternative Splicing of the Fibronectin EIIIB Exon Depends on Specific TGCATG Repeats
Lee P. Lim & Phillip A. Sharp
Pages: 3900-3906
Published online: 28 Mar 2023
AbstractforAlternative Splicing of the Fibronectin EIIIB Exon Depends on Specific TGCATG Repeats | Full Text | References | PDF (1 MB)
  • 14 Views
  • 74 CrossRef citations
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Article
Interaction between Major Nitrogen Regulatory Protein NIT2 and Pathway-Specific Regulatory Factor NIT4 Is Required for Their Synergistic Activation of Gene Expression in Neurospora crassa
Bo Feng & George A. Marzluf
Pages: 3983-3990
Published online: 28 Mar 2023
AbstractforInteraction between Major Nitrogen Regulatory Protein NIT2 and Pathway-Specific Regulatory Factor NIT4 Is Required for Their Synergistic Activation of Gene Expression in Neurospora crassa | Full Text | References | PDF (906.3 KB)
  • 21 Views
  • 55 CrossRef citations
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Article
In Vitro Genetic Analysis of the RNA Binding Site of Vigilin, a Multi-KH-Domain Protein
Hiroshi Kanamori, Robin E. Dodson & David J. Shapiro
Pages: 3991-4003
Published online: 28 Mar 2023
AbstractforIn Vitro Genetic Analysis of the RNA Binding Site of Vigilin, a Multi-KH-Domain Protein | Full Text | References | PDF (2.5 MB)
  • 8 Views
  • 37 CrossRef citations
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Article
RNA Binding Activity of Heterodimeric Splicing Factor U2AF: at Least One RS Domain Is Required for High-Affinity Binding
David Z. Rudner, Kevin S. Breger, Roland Kanaar, Melissa D. Adams & Donald C. Rio
Pages: 4004-4011
Published online: 28 Mar 2023
AbstractforRNA Binding Activity of Heterodimeric Splicing Factor U2AF: at Least One RS Domain Is Required for High-Affinity Binding | Full Text | References | PDF (1.2 MB)
  • 18 Views
  • 26 CrossRef citations
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Article
cis-Acting Signal for Inheritance of Imprinted DNA Methylation Patterns in the Preimplantation Mouse Embryo
Carina Y. Howell, Anita L. Steptoe, Michael W. Miller & J. Richard Chaillet
Pages: 4149-4156
Published online: 28 Mar 2023
Abstractforcis-Acting Signal for Inheritance of Imprinted DNA Methylation Patterns in the Preimplantation Mouse Embryo | Full Text | References | PDF (590.2 KB)
  • 9 Views
  • 20 CrossRef citations
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Article
Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion
Patrick A. Navas, Kenneth R. Peterson, Qiliang Li, Eva Skarpidi, Alex Rohde, Sara E. Shaw, Christopher H. Clegg, Haruhiko Asano & George Stamatoyannopoulos
Pages: 4188-4196
Published online: 28 Mar 2023
AbstractforDevelopmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion | Full Text | References | PDF (1.7 MB)
  • 12 Views
  • 74 CrossRef citations
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Article
Positive and Negative Autoregulation ofREB1 Transcription in Saccharomyces cerevisiae
Kevin L.-C. Wang & Jonathan R. Warner
Pages: 4368-4376
Published online: 28 Mar 2023
AbstractforPositive and Negative Autoregulation ofREB1 Transcription in Saccharomyces cerevisiae | Full Text | References | PDF (934.8 KB)
  • 10 Views
  • 16 CrossRef citations
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Dna Dynamics and Chromosome Structure

Article
Schistosome Satellite DNA Encodes Active Hammerhead Ribozymes
Gerardo Ferbeyre, James M. Smith & Robert Cedergren
Pages: 3880-3888
Published online: 28 Mar 2023
AbstractforSchistosome Satellite DNA Encodes Active Hammerhead Ribozymes | Full Text | References | PDF (1.3 MB)
  • 22 Views
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Article
Analysis of Gene Targeting and Intrachromosomal Homologous Recombination Stimulated by Genomic Double-Strand Breaks in Mouse Embryonic Stem Cells
Greg Donoho, Maria Jasin & Paul Berg
Pages: 4070-4078
Published online: 28 Mar 2023
AbstractforAnalysis of Gene Targeting and Intrachromosomal Homologous Recombination Stimulated by Genomic Double-Strand Breaks in Mouse Embryonic Stem Cells | Full Text | References | PDF (362.3 KB)
  • 37 Views
  • 137 CrossRef citations
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Article
The Capacity of Polyomavirus Enhancer Binding Protein 2αB (AML1/Cbfa2) To Stimulate Polyomavirus DNA Replication Is Related to Its Affinity for the Nuclear Matrix
Lin-Feng Chen, Kosei Ito, Yota Murakami & Yoshiaki Ito
Pages: 4165-4176
Published online: 28 Mar 2023
AbstractforThe Capacity of Polyomavirus Enhancer Binding Protein 2αB (AML1/Cbfa2) To Stimulate Polyomavirus DNA Replication Is Related to Its Affinity for the Nuclear Matrix | Full Text | References | PDF (3.2 MB)
  • 6 Views
  • 36 CrossRef citations
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Article
Cyclin-Dependent Kinase Inhibitor p21 Modulates the DNA Primer-Template Recognition Complex
Shou Waga & Bruce Stillman
Pages: 4177-4187
Published online: 28 Mar 2023
AbstractforCyclin-Dependent Kinase Inhibitor p21 Modulates the DNA Primer-Template Recognition Complex | Full Text | References | PDF (1.7 MB)
  • 18 Views
  • 59 CrossRef citations
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Article
Extensive, Nonrandom Diversity of Excision Footprints Generated by Ds-Like Transposon Ascot-1Suggests New Parallels with V(D)J Recombination
Vincent Colot, Vicki Haedens & Jean-Luc Rossignol
Pages: 4337-4346
Published online: 28 Mar 2023
AbstractforExtensive, Nonrandom Diversity of Excision Footprints Generated by Ds-Like Transposon Ascot-1Suggests New Parallels with V(D)J Recombination | Full Text | References | PDF (551.2 KB)
  • 8 Views
  • 40 CrossRef citations
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Article
Targeting to Transcriptionally Active Loci by the Hydrophilic N-Terminal Domain of Drosophila DNA Topoisomerase I
Wen-Ling Shaiu & Tao-shih Hsieh
Pages: 4358-4367
Published online: 28 Mar 2023
AbstractforTargeting to Transcriptionally Active Loci by the Hydrophilic N-Terminal Domain of Drosophila DNA Topoisomerase I | Full Text | References | PDF (1.3 MB)
  • 8 Views
  • 38 CrossRef citations
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Article
p48 Activates a UV-Damaged-DNA Binding Factor and Is Defective in Xeroderma Pigmentosum Group E Cells That Lack Binding Activity
Byung Joon Hwang, Stephanie Toering, Uta Francke & Gilbert Chu
Pages: 4391-4399
Published online: 28 Mar 2023
Abstractforp48 Activates a UV-Damaged-DNA Binding Factor and Is Defective in Xeroderma Pigmentosum Group E Cells That Lack Binding Activity | Full Text | References | PDF (2.1 MB)
  • 15 Views
  • 123 CrossRef citations
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Article
Studies of the Interaction between Rad52 Protein and the Yeast Single-Stranded DNA Binding Protein RPA
Sharon L. Hays, Antoine A. Firmenich, Philip Massey, Ronadip Banerjee & Paul Berg
Pages: 4400-4406
Published online: 28 Mar 2023
AbstractforStudies of the Interaction between Rad52 Protein and the Yeast Single-Stranded DNA Binding Protein RPA | Full Text | References | PDF (165.4 KB)
  • 61 Views
  • 102 CrossRef citations
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Errata

Correction
Regulation of Cell Size by Glucose Is Exerted via Repression of the CLN1 Promoter
Page: 4407
Published online: 28 Mar 2023
CitationforRegulation of Cell Size by Glucose Is Exerted via Repression of the CLN1 Promoter | Full Text | PDF (37.5 KB)
  • 85 Views
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