Molecular and Cellular Biology, Volume 21, Issue 22 (2001)

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Molecular and Cellular Biology, Volume 21, Issue 22 (2001)

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Transcriptional Regulation

Article
The Notch Intracellular Domain Can Function as a Coactivator for LEF-1
David A. Ross & Tom Kadesch
Pages: 7537-7544
Published online: 28 Mar 2023
AbstractforThe Notch Intracellular Domain Can Function as a Coactivator for LEF-1 | Full Text | References | PDF (739.5 KB)
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Article
Role of an ING1 Growth Regulator in Transcriptional Activation and Targeted Histone Acetylation by the NuA4 Complex
Amine Nourani, Yannick Doyon, Rhea T. Utley, Stéphane Allard, William S. Lane & Jacques Côté
Pages: 7629-7640
Published online: 28 Mar 2023
AbstractforRole of an ING1 Growth Regulator in Transcriptional Activation and Targeted Histone Acetylation by the NuA4 Complex | Full Text | References | PDF (588.6 KB)
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Article
Nucleosomes Are Translationally Positioned on the Active Allele and Rotationally Positioned on the Inactive Allele of the HPRT Promoter
Chien Chen & Thomas P. Yang
Pages: 7682-7695
Published online: 28 Mar 2023
AbstractforNucleosomes Are Translationally Positioned on the Active Allele and Rotationally Positioned on the Inactive Allele of the HPRT Promoter | Full Text | References | PDF (488.2 KB)
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Article
The gypsy Insulator Can Act as a Promoter-Specific Transcriptional Stimulator
Wei Wei & Mark D. Brennan
Pages: 7714-7720
Published online: 28 Mar 2023
AbstractforThe gypsy Insulator Can Act as a Promoter-Specific Transcriptional Stimulator | Full Text | References | PDF (107.4 KB)
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Article
p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1
Franz Oswald, Birgitt Täuber, Thomas Dobner, Soizic Bourteele, Ulrike Kostezka, Guido Adler, Susanne Liptay & Roland M. Schmid
Pages: 7761-7774
Published online: 28 Mar 2023
Abstractforp300 Acts as a Transcriptional Coactivator for Mammalian Notch-1 | Full Text | References | PDF (1.3 MB)
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Article
Initiator Recognition in a Primitive Eukaryote: IBP39, an Initiator-Binding Protein from Trichomonas vaginalis
David R. Liston, Audrey O. T. Lau, Diana Ortiz, Stephen T. Smale & Patricia J. Johnson
Pages: 7872-7882
Published online: 28 Mar 2023
AbstractforInitiator Recognition in a Primitive Eukaryote: IBP39, an Initiator-Binding Protein from Trichomonas vaginalis | Full Text | References | PDF (559 KB)
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Cell Growth and Development

Article
Trophic Factor Withdrawal: p38 Mitogen-Activated Protein Kinase Activates NHE1, Which Induces Intracellular Alkalinization
Annette R. Khaled, Andrea N. Moor, Aiqun Li, Kyungjae Kim, Douglas K. Ferris, Kathrin Muegge, Robert J. Fisher, Larry Fliegel & Scott K. Durum
Pages: 7545-7557
Published online: 28 Mar 2023
AbstractforTrophic Factor Withdrawal: p38 Mitogen-Activated Protein Kinase Activates NHE1, Which Induces Intracellular Alkalinization | Full Text | References | PDF (437.2 KB)
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Article
Autoregulation of the Human Liver X Receptor α Promoter
Bryan A. Laffitte, Sean B. Joseph, Robert Walczak, Liming Pei, Damien C. Wilpitz, Jon L. Collins & Peter Tontonoz
Pages: 7558-7568
Published online: 28 Mar 2023
AbstractforAutoregulation of the Human Liver X Receptor α Promoter | Full Text | References | PDF (576.9 KB)
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Article
Hsp104 Interacts with Hsp90 Cochaperones in Respiring Yeast
Toufik Abbas-Terki, Olivier Donzé, Pierre-André Briand & Didier Picard
Pages: 7569-7575
Published online: 28 Mar 2023
AbstractforHsp104 Interacts with Hsp90 Cochaperones in Respiring Yeast | Full Text | References | PDF (416.6 KB)
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Article
Distinct Effects of Mitogens and the Actin Cytoskeleton on CREB and Pocket Protein Phosphorylation Control the Extent and Timing of Cyclin A Promoter Activity
Maria Elena Bottazzi, Monica Buzzai, Xiaoyun Zhu, Chantal Desdouets, Christian Bréchot & Richard K. Assoian
Pages: 7607-7616
Published online: 28 Mar 2023
AbstractforDistinct Effects of Mitogens and the Actin Cytoskeleton on CREB and Pocket Protein Phosphorylation Control the Extent and Timing of Cyclin A Promoter Activity | Full Text | References | PDF (366.8 KB)
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Article
Mechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src
Paul J. Ruest, Nah-Young Shin, Thomas R. Polte, Xiaoe Zhang & Steven K. Hanks
Pages: 7641-7652
Published online: 28 Mar 2023
AbstractforMechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src | Full Text | References | PDF (624.7 KB)
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Article
Bax Loss Impairs Myc-Induced Apoptosis and Circumvents the Selection of p53 Mutations during Myc-Mediated Lymphomagenesis
Christine M. Eischen, Martine F. Roussel, Stanley J. Korsmeyer & John L. Cleveland
Pages: 7653-7662
Published online: 28 Mar 2023
AbstractforBax Loss Impairs Myc-Induced Apoptosis and Circumvents the Selection of p53 Mutations during Myc-Mediated Lymphomagenesis | Full Text | References | PDF (299.3 KB)
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Article
Identification of a Role for the Sialomucin CD164 in Myogenic Differentiation by Signal Sequence Trapping in Yeast
Youl-Nam Lee, Jong-Sun Kang & Robert S. Krauss
Pages: 7696-7706
Published online: 28 Mar 2023
AbstractforIdentification of a Role for the Sialomucin CD164 in Myogenic Differentiation by Signal Sequence Trapping in Yeast | Full Text | References | PDF (1.9 MB)
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Article
Mitochondrially Associated Hepatitis B Virus X Protein Constitutively Activates Transcription Factors STAT-3 and NF-κB via Oxidative Stress
Gulam Waris, Kyung-Won Huh & Aleem Siddiqui
Pages: 7721-7730
Published online: 28 Mar 2023
AbstractforMitochondrially Associated Hepatitis B Virus X Protein Constitutively Activates Transcription Factors STAT-3 and NF-κB via Oxidative Stress | Full Text | References | PDF (385 KB)
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Article
Huntingtin Interacting Protein 1 Is a Clathrin Coat Binding Protein Required for Differentiation of late Spermatogenic Progenitors
Dinesh S. Rao, Jenny C. Chang, Priti D. Kumar, Ikuko Mizukami, Glennda M. Smithson, Sarah V. Bradley, A. F. Parlow & Theodora S. Ross
Pages: 7796-7806
Published online: 28 Mar 2023
AbstractforHuntingtin Interacting Protein 1 Is a Clathrin Coat Binding Protein Required for Differentiation of late Spermatogenic Progenitors | Full Text | References | PDF (5 MB)
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Article
Activation of Protein Kinase Cζ Induces Serine Phosphorylation of VAMP2 in the GLUT4 Compartment and Increases Glucose Transport in Skeletal Muscle
Liora Braiman, Addy Alt, Toshio Kuroki, Motoi Ohba, Asia Bak, Tamar Tennenbaum & Sanford R. Sampson
Pages: 7852-7861
Published online: 28 Mar 2023
AbstractforActivation of Protein Kinase Cζ Induces Serine Phosphorylation of VAMP2 in the GLUT4 Compartment and Increases Glucose Transport in Skeletal Muscle | Full Text | References | PDF (517.8 KB)
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Cell and Organelle Structure and Assembly

Article
Overproduction of PDR3 Suppresses Mitochondrial Import Defects Associated with a TOM70 Null Mutation by Increasing the Expression of TOM72 in Saccharomyces cerevisiae
Julie Y. Koh, Petr Hájek & David M. Bedwell
Pages: 7576-7586
Published online: 28 Mar 2023
AbstractforOverproduction of PDR3 Suppresses Mitochondrial Import Defects Associated with a TOM70 Null Mutation by Increasing the Expression of TOM72 in Saccharomyces cerevisiae | Full Text | References | PDF (270.6 KB)
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Article
Peripheral Mitochondrial Inner Membrane Protein, Mss2p, Required for Export of the Mitochondrially Coded Cox2p C Tail in Saccharomyces cerevisiae
Sarah A. Broadley, Christina M. Demlow & Thomas D. Fox
Pages: 7663-7672
Published online: 28 Mar 2023
AbstractforPeripheral Mitochondrial Inner Membrane Protein, Mss2p, Required for Export of the Mitochondrially Coded Cox2p C Tail in Saccharomyces cerevisiae | Full Text | References | PDF (337.9 KB)
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Dna Dynamics and Chromosome Structure

Article
Reduced Rates of Gene Loss, Gene Silencing, and Gene Mutation in Dnmt1-Deficient Embryonic Stem Cells
Matilda F. Chan, Renée van Amerongen, Tarlochan Nijjar, Edwin Cuppen, Peter A. Jones & Peter W. Laird
Pages: 7587-7600
Published online: 28 Mar 2023
AbstractforReduced Rates of Gene Loss, Gene Silencing, and Gene Mutation in Dnmt1-Deficient Embryonic Stem Cells | Full Text | References | PDF (959.3 KB)
  • 11 Views
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Article
N-Terminal Domains of the Human Telomerase Catalytic Subunit Required for Enzyme Activity in Vivo
Blaine N. Armbruster, Soma S. R. Banik, Chuanhai Guo, Allyson C. Smith & Christopher M. Counter
Pages: 7775-7786
Published online: 28 Mar 2023
AbstractforN-Terminal Domains of the Human Telomerase Catalytic Subunit Required for Enzyme Activity in Vivo | Full Text | References | PDF (665.2 KB)
  • 94 Views
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Article
A Truncation Mutant of the 95-Kilodalton Subunit of Transcription Factor IIIC Reveals Asymmetry in Ty3 Integration
Michael Aye, Sandra L. Dildine, Jonathan A. Claypool, Sabine Jourdain & Suzanne B. Sandmeyer
Pages: 7839-7851
Published online: 28 Mar 2023
AbstractforA Truncation Mutant of the 95-Kilodalton Subunit of Transcription Factor IIIC Reveals Asymmetry in Ty3 Integration | Full Text | References | PDF (407.1 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
CpG Binding Protein Is Crucial for Early Embryonic Development
Diana L. Carlone & David G. Skalnik
Pages: 7601-7606
Published online: 28 Mar 2023
AbstractforCpG Binding Protein Is Crucial for Early Embryonic Development | Full Text | References | PDF (250 KB)
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Article
Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function
Byong Su Kim, Olga V. Savinova, Mark V. Reedy, Janice Martin, Yi Lun, Lin Gan, Richard S. Smith, Stanislav I. Tomarev, Simon W. M. John & Randy L. Johnson
Pages: 7707-7713
Published online: 28 Mar 2023
AbstractforTargeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function | Full Text | References | PDF (1.5 MB)
  • 63 Views
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Article
Srg3, a Mouse Homolog of Yeast SWI3, Is Essential for Early Embryogenesis and Involved in Brain Development
Joong K. Kim, Sung-Oh Huh, Heonsik Choi, Kee-Sook Lee, Dongho Shin, Changjin Lee, Ju-Suk Nam, Hyun Kim, Heekyoung Chung, Han W. Lee, Sang D. Park & Rho H. Seong
Pages: 7787-7795
Published online: 28 Mar 2023
AbstractforSrg3, a Mouse Homolog of Yeast SWI3, Is Essential for Early Embryogenesis and Involved in Brain Development | Full Text | References | PDF (1.1 MB)
  • 34 Views
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Article
Mice with a Targeted Deletion of the Tetranectin Gene Exhibit a Spinal Deformity
Kousuke Iba, Marian E. Durkin, Lise Johnsen, Ernst Hunziker, Karen Damgaard-Pedersen, Hong Zhang, Eva Engvall, Reidar Albrechtsen & Ulla M. Wewer
Pages: 7817-7825
Published online: 28 Mar 2023
AbstractforMice with a Targeted Deletion of the Tetranectin Gene Exhibit a Spinal Deformity | Full Text | References | PDF (1.5 MB)
  • 39 Views
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Gene Expression

Article
The Transcription Elongation Factor CA150 Interacts with RNA Polymerase II and the Pre-mRNA Splicing Factor SF1
Aaron C. Goldstrohm, Todd R. Albrecht, Carles Suñé, Mark T. Bedford & Mariano A. Garcia-Blanco
Pages: 7617-7628
Published online: 28 Mar 2023
AbstractforThe Transcription Elongation Factor CA150 Interacts with RNA Polymerase II and the Pre-mRNA Splicing Factor SF1 | Full Text | References | PDF (421.5 KB)
  • 30 Views
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Article
Dual Function for U2AF35 in AG-Dependent Pre-mRNA Splicing
Sabine Guth, Thomas ∅. Tange, Esther Kellenberger & Juan Valcárcel
Pages: 7673-7681
Published online: 28 Mar 2023
AbstractforDual Function for U2AF35 in AG-Dependent Pre-mRNA Splicing | Full Text | References | PDF (316.5 KB)
  • 32 Views
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Article
A Well-Connected and Conserved Nucleoplasmic Helicase Is Required for Production of Box C/D and H/ACA snoRNAs and Localization of snoRNP Proteins
Thomas H. King, Wayne A. Decatur, Edouard Bertrand, E. Stuart Maxwell & Maurille J. Fournier
Pages: 7731-7746
Published online: 28 Mar 2023
AbstractforA Well-Connected and Conserved Nucleoplasmic Helicase Is Required for Production of Box C/D and H/ACA snoRNAs and Localization of snoRNP Proteins | Full Text | References | PDF (2.2 MB)
  • 30 Views
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Article
RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization
Hélène Tourrière, Imed-eddine Gallouzi, Karim Chebli, Jean Paul Capony, John Mouaikel, Peter van der Geer & Jamal Tazi
Pages: 7747-7760
Published online: 28 Mar 2023
AbstractforRasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization | Full Text | References | PDF (942.5 KB)
  • 139 Views
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Article
Specific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells
Shicheng Yang, Stephen Tutton, Eric Pierce & Kyonggeun Yoon
Pages: 7807-7816
Published online: 28 Mar 2023
AbstractforSpecific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells | Full Text | References | PDF (1.5 MB)
  • 58 Views
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Nucleocytoplasmic Communication

Article
Integrase Mediates Nuclear Localization of Ty3
Sophia S. Lin, M. Henrietta Nymark-McMahon, Lynn Yieh & Suzanne B. Sandmeyer
Pages: 7826-7838
Published online: 28 Mar 2023
AbstractforIntegrase Mediates Nuclear Localization of Ty3 | Full Text | References | PDF (1.7 MB)
  • 8 Views
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Article
CRM1 Mediates the Export of ADAR1 through a Nuclear Export Signal within the Z-DNA Binding Domain
Hanne Poulsen, Jakob Nilsson, Christian K. Damgaard, Jan Egebjerg & Jørgen Kjems
Pages: 7862-7871
Published online: 28 Mar 2023
AbstractforCRM1 Mediates the Export of ADAR1 through a Nuclear Export Signal within the Z-DNA Binding Domain | Full Text | References | PDF (349.7 KB)
  • 90 Views
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