Molecular and Cellular Biology, Volume 26, Issue 6 (2006)

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Molecular and Cellular Biology, Volume 26, Issue 6 (2006)

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Articles

Article
Histone Deacetylase Inhibitors Induce VHL and Ubiquitin-Independent Proteasomal Degradation of Hypoxia-Inducible Factor 1α
Xianguo Kong, Zhao Lin, Dongming Liang, Donna Fath, Nianli Sang & Jaime Caro
Pages: 2019-2028
Published online: 27 Mar 2023
AbstractforHistone Deacetylase Inhibitors Induce VHL and Ubiquitin-Independent Proteasomal Degradation of Hypoxia-Inducible Factor 1α | Full Text | References | PDF (396.9 KB)
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Article
A Novel RNA Binding Domain in Tetrahymena Telomerase p65 Initiates Hierarchical Assembly of Telomerase Holoenzyme
Catherine M. O'Connor & Kathleen Collins
Pages: 2029-2036
Published online: 27 Mar 2023
AbstractforA Novel RNA Binding Domain in Tetrahymena Telomerase p65 Initiates Hierarchical Assembly of Telomerase Holoenzyme | Full Text | References | PDF (531.5 KB)
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Article
Generation and Characterization of Telomere Length Maintenance in Tankyrase 2-Deficient Mice
Y. Jeffrey Chiang, My-Linh Nguyen, Sujatha Gurunathan, Patrick Kaminker, Lino Tessarollo, Judith Campisi & Richard J. Hodes
Pages: 2037-2043
Published online: 27 Mar 2023
AbstractforGeneration and Characterization of Telomere Length Maintenance in Tankyrase 2-Deficient Mice | Full Text | References | PDF (300.1 KB)
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Article
Tankyrase 2 Poly(ADP-Ribose) Polymerase Domain-Deleted Mice Exhibit Growth Defects but Have Normal Telomere Length and Capping
Susan J. Hsiao, Marc F. Poitras, Brandoch D. Cook, Yie Liu & Susan Smith
Pages: 2044-2054
Published online: 27 Mar 2023
AbstractforTankyrase 2 Poly(ADP-Ribose) Polymerase Domain-Deleted Mice Exhibit Growth Defects but Have Normal Telomere Length and Capping | Full Text | References | PDF (481.9 KB)
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Article
Novel Cross Talk of Krüppel-Like Factor 4 and β-Catenin Regulates Normal Intestinal Homeostasis and Tumor Repression
Wen Zhang, Xi Chen, Yoichi Kato, Paul M. Evans, Subo Yuan, Jun Yang, Piotr G. Rychahou, Vincent W. Yang, Xi He, B. Mark Evers & Chunming Liu
Pages: 2055-2064
Published online: 27 Mar 2023
AbstractforNovel Cross Talk of Krüppel-Like Factor 4 and β-Catenin Regulates Normal Intestinal Homeostasis and Tumor Repression | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
PB1 Domain-Dependent Signaling Complex Is Required for Extracellular Signal-Regulated Kinase 5 Activation
Kazuhiro Nakamura, Mark T. Uhlik, Nancy L. Johnson, Klaus M. Hahn & Gary L. Johnson
Pages: 2065-2079
Published online: 27 Mar 2023
AbstractforPB1 Domain-Dependent Signaling Complex Is Required for Extracellular Signal-Regulated Kinase 5 Activation | Full Text | References | PDF (1.2 MB)
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Article
Inflammatory Disease and Lymphomagenesis Caused by Deletion of the Myc Antagonist Mnt in T Cells
Shala Dezfouli, Antony Bakke, Jie Huang, Anthony Wynshaw-Boris & Peter J. Hurlin
Pages: 2080-2092
Published online: 27 Mar 2023
AbstractforInflammatory Disease and Lymphomagenesis Caused by Deletion of the Myc Antagonist Mnt in T Cells | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Normal Cells, but Not Cancer Cells, Survive Severe Plk1 Depletion
Xiaoqi Liu, Ming Lei & Raymond L. Erikson
Pages: 2093-2108
Published online: 27 Mar 2023
AbstractforNormal Cells, but Not Cancer Cells, Survive Severe Plk1 Depletion | Full Text | References | PDF (2.1 MB)
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Article
Differential Methylation of Xite and CTCF Sites in Tsix Mirrors the Pattern of X-Inactivation Choice in Mice
Rebecca Maxfield Boumil, Yuya Ogawa, Bryan K. Sun, Khanh D. Huynh & Jeannie T. Lee
Pages: 2109-2117
Published online: 27 Mar 2023
AbstractforDifferential Methylation of Xite and CTCF Sites in Tsix Mirrors the Pattern of X-Inactivation Choice in Mice | Full Text | References | PDF (626.7 KB)
  • 6 Views
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Article
p38 Mitogen-Activated Protein Kinase Mediates the Fas-Induced Mitochondrial Death Pathway in CD8+ T Cells
Nicholas Farley, Gustavo Pedraza-Alva, Diego Serrano-Gomez, Viswas Nagaleekar, Alexander Aronshtam, Troy Krahl, Tina Thornton & Mercedes Rincón
Pages: 2118-2129
Published online: 27 Mar 2023
Abstractforp38 Mitogen-Activated Protein Kinase Mediates the Fas-Induced Mitochondrial Death Pathway in CD8+ T Cells | Full Text | References | PDF (789.5 KB) | Supplemental
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Article
Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation
Zhiping Wang, Tara J. Dillon, Viji Pokala, Snigdha Mishra, Kirstin Labudda, Brian Hunter & Philip J. S. Stork
Pages: 2130-2145
Published online: 27 Mar 2023
AbstractforRap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation | Full Text | References | PDF (861.7 KB)
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Article
Regulation of Cellular Immortalization and Steady-State Levels of the Telomerase Reverse Transcriptase through Its Carboxy-Terminal Domain
Elaine J. Middleman, Jinkuk Choi, Andrew S. Venteicher, Peggie Cheung & Steven E. Artandi
Pages: 2146-2159
Published online: 27 Mar 2023
AbstractforRegulation of Cellular Immortalization and Steady-State Levels of the Telomerase Reverse Transcriptase through Its Carboxy-Terminal Domain | Full Text | References | PDF (610.7 KB) | Supplemental
  • 9 Views
  • 15 CrossRef citations
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Article
Involvement of Rac1 in Activation of Multicomponent Nox1- and Nox3-Based NADPH Oxidases
Takehiko Ueyama, Miklós Geiszt & Thomas L. Leto
Pages: 2160-2174
Published online: 27 Mar 2023
AbstractforInvolvement of Rac1 in Activation of Multicomponent Nox1- and Nox3-Based NADPH Oxidases | Full Text | References | PDF (1.5 MB)
  • 41 Views
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Article
Myosin VI Is a Mediator of the p53-Dependent Cell Survival Pathway
Eun Joo Jung, Gang Liu, Wenjing Zhou & Xinbin Chen
Pages: 2175-2186
Published online: 27 Mar 2023
AbstractforMyosin VI Is a Mediator of the p53-Dependent Cell Survival Pathway | Full Text | References | PDF (1.1 MB)
  • 10 Views
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Article
A Regulated Nucleocytoplasmic Shuttle Contributes to Bright's Function as a Transcriptional Activator of Immunoglobulin Genes
Dongkyoon Kim & Philip W. Tucker
Pages: 2187-2201
Published online: 27 Mar 2023
AbstractforA Regulated Nucleocytoplasmic Shuttle Contributes to Bright's Function as a Transcriptional Activator of Immunoglobulin Genes | Full Text | References | PDF (995 KB)
  • 19 Views
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Article
The Molecular Scaffold Kinase Suppressor of Ras 1 Is a Modifier of RasV12-Induced and Replicative Senescence
Robert L. Kortum, Heidi J. Johnson, Diane L. Costanzo, Deanna J. Volle, Gina L. Razidlo, Angela M. Fusello, Andrey S. Shaw & Robert E. Lewis
Pages: 2202-2214
Published online: 27 Mar 2023
AbstractforThe Molecular Scaffold Kinase Suppressor of Ras 1 Is a Modifier of RasV12-Induced and Replicative Senescence | Full Text | References | PDF (923.7 KB)
  • 28 Views
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Article
Inhibition of ADP/ATP Exchange in Receptor-Interacting Protein-Mediated Necrosis
Vladislav Temkin, Qiquan Huang, Hongtao Liu, Hiroyuki Osada & Richard M. Pope
Pages: 2215-2225
Published online: 27 Mar 2023
AbstractforInhibition of ADP/ATP Exchange in Receptor-Interacting Protein-Mediated Necrosis | Full Text | References | PDF (376.1 KB) | Supplemental
  • 27 Views
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Article
Condensin Loaded onto the Replication Fork Barrier Site in the rRNA Gene Repeats during S Phase in a FOB1-Dependent Fashion To Prevent Contraction of a Long Repetitive Array in Saccharomyces cerevisiae
Katsuki Johzuka, Masahiro Terasawa, Hideyuki Ogawa, Tomoko Ogawa & Takashi Horiuchi
Pages: 2226-2236
Published online: 27 Mar 2023
AbstractforCondensin Loaded onto the Replication Fork Barrier Site in the rRNA Gene Repeats during S Phase in a FOB1-Dependent Fashion To Prevent Contraction of a Long Repetitive Array in Saccharomyces cerevisiae | Full Text | References | PDF (778.7 KB) | Supplemental
  • 17 Views
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Article
An Apparent Pseudo-Exon Acts both as an Alternative Exon That Leads to Nonsense-Mediated Decay and as a Zero-Length Exon
Sushma-Nagaraja Grellscheid & Christopher W. J. Smith
Pages: 2237-2246
Published online: 27 Mar 2023
AbstractforAn Apparent Pseudo-Exon Acts both as an Alternative Exon That Leads to Nonsense-Mediated Decay and as a Zero-Length Exon | Full Text | References | PDF (642.1 KB)
  • 31 Views
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Article
A Spatiotemporally Coordinated Cascade of Protein Kinase C Activation Controls Isoform-Selective Translocation
Alejandra Collazos, Barthélémy Diouf, Nathalie C. Guérineau, Corinne Quittau-Prévostel, Marion Peter, Fanny Coudane, Frédéric Hollande & Dominique Joubert
Pages: 2247-2261
Published online: 27 Mar 2023
AbstractforA Spatiotemporally Coordinated Cascade of Protein Kinase C Activation Controls Isoform-Selective Translocation | Full Text | References | PDF (988.2 KB) | Supplemental
  • 9 Views
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Article
Regulation and Role of Raf-1/B-Raf Heterodimerization
Linda K. Rushworth, Alison D. Hindley, Eric O'Neill & Walter Kolch
Pages: 2262-2272
Published online: 27 Mar 2023
AbstractforRegulation and Role of Raf-1/B-Raf Heterodimerization | Full Text | References | PDF (534.1 KB) | Supplemental
  • 109 Views
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Article
CARM1 Regulates Proliferation of PC12 Cells by Methylating HuD
Tatsuji Fujiwara, Yasutake Mori, Dong Ling Chu, Yoshihisa Koyama, Shingo Miyata, Hiroyuki Tanaka, Kohji Yachi, Tateki Kubo, Hideki Yoshikawa & Masaya Tohyama
Pages: 2273-2285
Published online: 27 Mar 2023
AbstractforCARM1 Regulates Proliferation of PC12 Cells by Methylating HuD | Full Text | References | PDF (555.5 KB)
  • 33 Views
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Article
A Family Knockout of All Four Drosophila Metallothioneins Reveals a Central Role in Copper Homeostasis and Detoxification
Dieter Egli, Hasmik Yepiskoposyan, Anand Selvaraj, Kuppusamy Balamurugan, Rama Rajaram, Andreas Simons, Gerd Multhaup, Simone Mettler, Alla Vardanyan, Oleg Georgiev & Walter Schaffner
Pages: 2286-2296
Published online: 27 Mar 2023
AbstractforA Family Knockout of All Four Drosophila Metallothioneins Reveals a Central Role in Copper Homeostasis and Detoxification | Full Text | References | PDF (632.6 KB) | Supplemental
  • 46 Views
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Article
The Biological Impact of the Human Master Regulator p53 Can Be Altered by Mutations That Change the Spectrum and Expression of Its Target Genes
Daniel Menendez, Alberto Inga & Michael A. Resnick
Pages: 2297-2308
Published online: 27 Mar 2023
AbstractforThe Biological Impact of the Human Master Regulator p53 Can Be Altered by Mutations That Change the Spectrum and Expression of Its Target Genes | Full Text | References | PDF (440.1 KB) | Supplemental
  • 23 Views
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Article
Murine Cathepsin F Deficiency Causes Neuronal Lipofuscinosis and Late-Onset Neurological Disease
Chi-Hui Tang, Je-Wook Lee, Michael G. Galvez, Liliane Robillard, Sara E. Mole & Harold A. Chapman
Pages: 2309-2316
Published online: 27 Mar 2023
AbstractforMurine Cathepsin F Deficiency Causes Neuronal Lipofuscinosis and Late-Onset Neurological Disease | Full Text | References | PDF (891.4 KB) | Supplemental
  • 50 Views
  • 59 CrossRef citations
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Article
Generation and Characterization of dickkopf3 Mutant Mice
Ivan del Barco Barrantes, Ana Montero-Pedrazuela, Ana Guadaño-Ferraz, Maria-Jesus Obregon, Raquel Martinez de Mena, Valérie Gailus-Durner, Helmut Fuchs, Tobias J. Franz, Svetoslav Kalaydjiev, Martina Klempt, Sabine Hölter, Birgit Rathkolb, Claudia Reinhard, Gabriella Morreale de Escobar, Juan Bernal, Dirk H. Busch, Wolfgang Wurst, Eckhard Wolf, Holger Schulz, Svetlana Shtrom, Erich Greiner, Martin Hrabé de Angelis, Heiner Westphal & Christof Niehrs
Pages: 2317-2326
Published online: 27 Mar 2023
AbstractforGeneration and Characterization of dickkopf3 Mutant Mice | Full Text | References | PDF (373.3 KB)
  • 41 Views
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Article
CARMA1 Is Required for Akt-Mediated NF-κB Activation in T Cells
Preeti Narayan, Brittany Holt, Richard Tosti & Lawrence P. Kane
Pages: 2327-2336
Published online: 27 Mar 2023
AbstractforCARMA1 Is Required for Akt-Mediated NF-κB Activation in T Cells | Full Text | References | PDF (460 KB)
  • 16 Views
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Article
Supramolecular Complexes Mediate Selenocysteine Incorporation In Vivo
Andrea Small-Howard, Nadya Morozova, Zoia Stoytcheva, Erin P. Forry, John B. Mansell, John W. Harney, Bradley A. Carlson, Xue-ming Xu, Dolph L. Hatfield & Marla J. Berry
Pages: 2337-2346
Published online: 27 Mar 2023
AbstractforSupramolecular Complexes Mediate Selenocysteine Incorporation In Vivo | Full Text | References | PDF (537.3 KB)
  • 38 Views
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Article
Nipped-A, the Tra1/TRRAP Subunit of the Drosophila SAGA and Tip60 Complexes, Has Multiple Roles in Notch Signaling during Wing Development
Maria Gause, Joel C. Eissenberg, Amy F. MacRae, Maia Dorsett, Ziva Misulovin & Dale Dorsett
Pages: 2347-2359
Published online: 27 Mar 2023
AbstractforNipped-A, the Tra1/TRRAP Subunit of the Drosophila SAGA and Tip60 Complexes, Has Multiple Roles in Notch Signaling during Wing Development | Full Text | References | PDF (739.9 KB)
  • 38 Views
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Article
Targeting of C-Terminal Binding Protein (CtBP) by ARF Results in p53-Independent Apoptosis
Seema Paliwal, Sandhya Pande, Ramesh C. Kovi, Norman E. Sharpless, Nabeel Bardeesy & Steven R. Grossman
Pages: 2360-2372
Published online: 27 Mar 2023
AbstractforTargeting of C-Terminal Binding Protein (CtBP) by ARF Results in p53-Independent Apoptosis | Full Text | References | PDF (650.5 KB)
  • 22 Views
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Article
Activation of Transferrin Receptor 1 by c-Myc Enhances Cellular Proliferation and Tumorigenesis
Kathryn A. O'Donnell, Duonan Yu, Karen I. Zeller, Jung-whan Kim, Frederick Racke, Andrei Thomas-Tikhonenko & Chi V. Dang
Pages: 2373-2386
Published online: 27 Mar 2023
AbstractforActivation of Transferrin Receptor 1 by c-Myc Enhances Cellular Proliferation and Tumorigenesis | Full Text | References | PDF (1.5 MB) | Supplemental
  • 119 Views
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Article
Regulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA
Tony Sourisseau, Anastasios Georgiadis, Anna Tsapara, Robin R. Ali, Richard Pestell, Karl Matter & Maria S. Balda
Pages: 2387-2398
Published online: 27 Mar 2023
AbstractforRegulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA | Full Text | References | PDF (661.5 KB) | Supplemental
  • 85 Views
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Article
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element
Edward Hitti, Tatiana Iakovleva, Matthew Brook, Stefanie Deppenmeier, Achim D. Gruber, Danuta Radzioch, Andrew R. Clark, Perry J. Blackshear, Alexey Kotlyarov & Matthias Gaestel
Pages: 2399-2407
Published online: 27 Mar 2023
AbstractforMitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element | Full Text | References | PDF (603.1 KB)
  • 74 Views
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Article
Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways
Matthew Brook, Carmen R. Tchen, Tomas Santalucia, Joanne McIlrath, J. Simon C. Arthur, Jeremy Saklatvala & Andrew R. Clark
Pages: 2408-2418
Published online: 27 Mar 2023
AbstractforPosttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways | Full Text | References | PDF (484.9 KB)
  • 42 Views
  • 206 CrossRef citations
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Article
A Nucleolin-Binding 3′ Untranslated Region Element Stabilizes β-Globin mRNA In Vivo
Yong Jiang, Xiang-Sheng Xu & J. Eric Russell
Pages: 2419-2429
Published online: 27 Mar 2023
AbstractforA Nucleolin-Binding 3′ Untranslated Region Element Stabilizes β-Globin mRNA In Vivo | Full Text | References | PDF (491.6 KB)
  • 73 Views
  • 67 CrossRef citations
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Article
Phosphorylation of the Cyclin-Dependent Kinase Inhibitor p21Cip1 on Serine 130 Is Essential for Viral Cyclin-Mediated Bypass of a p21Cip1-Imposed G1 Arrest
Annika Järviluoma, Emma S. Child, Grzegorz Sarek, Papinya Sirimongkolkasem, Gordon Peters, Päivi M. Ojala & David J. Mann
Pages: 2430-2440
Published online: 27 Mar 2023
AbstractforPhosphorylation of the Cyclin-Dependent Kinase Inhibitor p21Cip1 on Serine 130 Is Essential for Viral Cyclin-Mediated Bypass of a p21Cip1-Imposed G1 Arrest | Full Text | References | PDF (341.2 KB)
  • 15 Views
  • 39 CrossRef citations
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Article
The p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase
Laurent Sansregret, Brigitte Goulet, Ryoko Harada, Brian Wilson, Lam Leduy, Jacques Bertoglio & Alain Nepveu
Pages: 2441-2455
Published online: 27 Mar 2023
AbstractforThe p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase | Full Text | References | PDF (849.9 KB)
  • 29 Views
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Article
Distinct Mechanisms Control the Stability of the Related S-Phase Cyclins Clb5 and Clb6
Leisa P. Jackson, Steven I. Reed & Steven B. Haase
Pages: 2456-2466
Published online: 27 Mar 2023
AbstractforDistinct Mechanisms Control the Stability of the Related S-Phase Cyclins Clb5 and Clb6 | Full Text | References | PDF (488.1 KB) | Supplemental
  • 35 Views
  • 45 CrossRef citations
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