Table of Contents
Xenobiotica
November 2009, Volume 39, Number 11
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Research Article


 
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes
K. Murai, H. Yamazaki, K. Nakagawa, R. Kawai, T. Kamataki
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 795-802, DOI 10.3109/00498250903171395.
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In vitro model for the prediction of clinical CYP3A4 induction using HepaRG cells
A. Kaneko, M. Kato, N. Sekiguchi, T. Mitsui, K. Takeda, Y. Aso
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 803-810, DOI 10.3109/00498250903184018.
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Metabolite screening of aromatic amine hair dyes using in vitro hepatic models
J. A. Skare, N. J. Hewitt, E. Doyle, R. Powrie, C. Elcombe
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 811-825, DOI 10.3109/00498250903134443.
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Studies on induction of lamotrigine metabolism in transgenic UGT1 mice
U. A. Argikar, K. Senekeo-Effenberger, E. E. Larson, R. H. Tukey, R. P. Remmel
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 826-835, DOI 10.3109/00498250903188985.
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Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel
Y. Nishiya, K. Hagihara, A. Kurihara, N. Okudaira, N.A. Farid, O. Okazaki, T. Ikeda
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 836-843, DOI 10.3109/00498250903191427.
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Effect of bifendate on the pharmacokinetics of talinolol in healthy subjects
Y. Zeng, F.-Y. He, Y.-J. He, L.-L. Dai, L. Fan, H.-H. Zhou
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 844-849, DOI 10.3109/00498250903111870.
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Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally bioavailable systemic Hedgehog signalling pathway inhibitor
H. Wong, J.Z. Chen, B. Chou, J.S. Halladay, J.R. Kenny, H. La, J.C. Marsters Jr, E. Plise, P.J. Rudewicz, K. Robarge, Y. Shin, S. Wong, C. Zhang, S.C. Khojasteh
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 850-861, DOI 10.3109/00498250903180289.
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Pharmacokinetics and anti-inflammatory pharmacodynamics of prednisolone in cynomolgus monkey
Y.J. Zheng, M. Hawk, H. Yuan, H.R. Hope, M. Baratta, A. Zutshi
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 862-870, DOI 10.3109/00498250903189454.
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Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice
J. Kuze, T. Mutoh, T. Takenaka, K. Morisaki, H. Nakura, N. Hanioka, S. Narimatsu
Xenobiotica, November 2009, Vol. 39, No. 11, Pages 871-880, DOI 10.3109/00498250903215382.
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