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Reviews

Russian vaccines against especially dangerous bacterial pathogens

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Pages 1-17 | Received 23 Sep 2015, Accepted 02 Nov 2015, Published online: 25 Jan 2019
 

Abstract

In response to the epidemiological situation, live attenuated or killed vaccines against anthrax, brucellosis, cholera, glanders, plague and tularemia were developed and used for immunization of at-risk populations in the Former Soviet Union. Certain of these vaccines have been updated and currently they are used on a selective basis, mainly for high risk occupations, in the Russian Federation. Except for anthrax and cholera these vaccines currently are the only licensed products available for protection against the most dangerous bacterial pathogens. Development of improved formulations and new products is ongoing.

This work was supported by a grant from the Defense Threat Reduction Agency (HDTRA1-11-1-0032) to Vladimir L Motin and by a subaward with the University of Texas Medical Branch at Galveston (NO 13-091) to Valentina A Feodorova.