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Original

Randomized controlled trials in psychiatry. Part 1: methodology and critical evaluation

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Pages 257-264 | Received 13 Dec 2002, Accepted 13 Dec 2002, Published online: 07 Aug 2009
 

Abstract

Objective: To introduce clinicians to the methodology and critical appraisal of randomized controlled trials (RCTs) in psychiatry.

Method: The methodology of RCTs in psychiatry is discussed. Using a systematic approach to critical appraisal, a published RCT of treatments for severe depression is examined and evaluated.

Results and Conclusions: The RCT appraised illustrates certain problematic areas in the methodology of trials in psychiatry. A detailed knowledge of methodology and critique of RCTs is essential in determining whether reported results will influence clinicians’ practice.

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