Abstract
Changes in self-reported mood assessed by the Beck Depression Inventory (BDI) were examined in a sample of 60 left-hemisphere speech-dominant patients who underwent epilepsy surgery (15 right frontal, 15 left frontal, 15 right temporal, 15 left temporal). Temporal lobectomy patients were matched to frontal lobectomy patients by presurgical BDI scores, premorbid K-BIT composite IQ, sex, age, and years since seizure onset. Overall, self-reported mood improved following surgery, with men showing a greater improvement than women. There were no differences among the four groups in terms of pre-surgical and post-surgical reported mood. However, frontal patients showed more extreme changes in mood in either direction than temporal patients. Additionally, while temporal patients showed gains in Composite IQ, no such gains were observed in frontal patients. Changes in mood in frontal patients were not related to postsurgical seizure outcome or time since surgery, but were related to changes in Composite IQ.