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Original Articles

Semantic Priming in Parkinsons Disease: Evidence for Delayed Spreading Activation

Pages 502-519 | Published online: 09 Aug 2010
 

Abstract

Nineteen persons with Parkinsons disease (PD) and 19 matched control participants completed a battery of online lexical decision tasks designed to isolate the automatic and attentional aspects of semantic activation within the semantic priming paradigm. Results highlighted key processing abnormalities in PD. Specifically, persons with PD exhibited a delayed time course of semantic activation. In addition, results suggest that experimental participants were unable to implicitly process prime information and, therefore, failed to engage strategic processing mechanisms in response to manipulations of the relatedness proportion. Results are discussed in terms of the Gain/Decay hypothesis (Milberg, McGlinchey-Berroth, Duncan, Higgins, 1999) and the dopaminergic modulation of signal to noise ratios in semantic networks.

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