Pharmacological Study of Mentha longifolia Phenolic Extracts

N Mimica-Dukiç Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovia 3,21 000 Novi Sad, Yugoslavia

V Jakovljeviç Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovia 3,21 000 Novi Sad, Yugoslavia

P Mira Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovia 3,21 000 Novi Sad, Yugoslavia

O Gasiç Faculty of Medicine, Department of Pharmacology, Toxicology and Clinical Pharmacology,University of Novi Sad, 21 000 Novi Sad, Yugoslavia

A Szabo Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovia 3,21 000 Novi Sad, Yugoslavia

Abstract

The effect of M. longifolia crude ethanol extract (F1), as well as fractions rich in luteolin glycosides (F2), apigenin glycosides (F3) and phenolic acids (F4) on intestine motility, spontaneous motility, pentobarbital induced sleep and bile secretion have been investigated. The crude ethanol extract was effective only on intestinal motility, apigenin and luteolin glycosides active on spontaneous motility. Phenolic acids were found to possess significant spasmodic, choleretic and CNS stimulative effects.

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Pharmacological Study of Mentha longifolia Phenolic Extracts

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Pharmacological Study of Mentha longifolia Phenolic Extracts

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