Chemical Investigation, Anti-inflammatory and Wound Healing Properties of Coronopus didymus

K.R. Prabhakar Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Manipal, Karnataka, India; Department of Pharmacology, Kasturba Medical College, Manipal, Karnataka, India

K.K. Srinivasan Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Manipal, Karnataka, India; Department of Pharmacology, Kasturba Medical College, Manipal, Karnataka, India

Padma. G.M. Rao Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Manipal, Karnataka, India; Department of Pharmacology, Kasturba Medical College, Manipal, Karnataka, India

Abstract

A systematic chemical investigation of Coronopus didymus was undertaken. A new flavone glycoside, viz., chrysoeriol-(6?-OAc)-4'-ß-D-glucoside, along with free chrysoeriol and stigmastanol, were isolated and characterized on the basis of chemical and spectral studies. The ethanol and aqueous extracts of the whole plant were subjected to antiinflammatory and wound healing activity studies. Both ethanol and aqueous extracts showed statistically significant wound healing activity, whereas only the aqueous extract showed significant anti-inflammatory activity.

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Chemical Investigation, Anti-inflammatory and Wound Healing Properties of Coronopus didymus

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Chemical Investigation, Anti-inflammatory and Wound Healing Properties of Coronopus didymus

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