![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Purpose : The objective of this study was to assess the effecacy of clip application in the surgical repair of iatrogenic colonic perforations.
Material andMethods : Twenty adult male Wistar-Albino rats were divided into two equal groups of ten. In both of the groups an iatrogenic perforation was made in the anti-mesenteric border of the left colon. The defect was closed with interrupted 6/0 polypropylene sutures in group 1 and extraluminal application of vascular clips (VCS-vascular clip system) in group 2. All animals were killed on postoperative Day 4. Wound healing was evaluated with both in situ bursting pressure and hydroxyproline levels.
Results : There was no statistically significant difference between the two groups in respect of bursting pressure levels (p = 0.063) whereas hydroxyproline levels were higher in group 2 (p = 0.0021).
Conclusions : Surgical repair of iatrogenic colonic perforations by extraluminal clips gives comparable results according to wound healing parameters. This approach may be a rational alternative to suture or endoscopic repair methods.
Key Words:
Additional information
Notes on contributors
T. Karahasanoglu
Prof. T. Karahasanoglu, M.D. B5 Blok D: 50 9. Kisim Akatöy 34750 Istanbul, Turkey Tel.: +90 212 559 71 47 Fax: +90 212 633 48 41 E-mail: [email protected]