![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Background : Graft failure is a significant problem following lower limb revascularisation. We hypothesised that the neutrophil-lymphocyte ratio (NLR), a simple and inexpensive index of systemic inflammation, predicts graft failure.
Methods : Consecutive patients undergoing infra-inguinal bypass grafting were identified from a prospective database. All patients underwent routine graft surveillance using Duplex ultrasound. Potential predictors of graft failure (occlusion or ipsilateral amputation) were assessed in univariate and multivariate regression models.
Results : Of 126 patients, 79 had patent grafts at 1 year. The only independent predictor of graft failure was the postoperative NLR.
Conclusion : Post-operative NLR may be a simple, inexpensive means of focussing surveillance resources on patients at high-risk of graft failure. Its value needs to be confirmed in larger cohorts.
Additional information
Notes on contributors
P. Kullar
P. Kullar, M.R.c.S. Vascular Surgery Department, Box 201 cambridge university Hospitals NHS Foundation Trust Hills Road cambridge cB2 0QQ united Kingdom E-mail: [email protected]