Role of lifestyle modifications for patients with laryngeal granuloma caused by gastro-esophageal reflux: comparison between conservative treatment and the surgical approach

Rika KobayashiDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan;

Koichi TsunodaDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; ;Department of Otolaryngology, University of Tokyo, Tokyo, JapanCorrespondence[email protected]

Rumi UehaDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; ;Department of Otolaryngology, University of Tokyo, Tokyo, Japan

Yoko FujimakiDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; ;Department of Otolaryngology, University of Tokyo, Tokyo, Japan

Takaharu NitoDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; ;Department of Otolaryngology, University of Tokyo, Tokyo, Japan

Tatsuya YamasobaDepartment of Artificial Organs and Medical Creation, and Otolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan;

Abstract

Conclusions: It is considered that a regimen combining pharmacologic management and lifestyle modifications is the most effective treatment for laryngeal granulomas caused by GER.

Objectives: This study compared the results of the combination therapy and surgery to determine the best treatment of laryngeal granuloma caused by gastro-esophageal reflux in 51 patients.

Methods: Prospective study.

Results: In the conservative treatment group, the CR rate was 89.7% and recurrence rate was 2.6%, while the lesions remained in patients (7.7%). This study compared the CR and recurrence rates between conservative treatment and surgery for granuloma. The results showed that the laryngeal granuloma recurrence rate was significantly lower with the conservative treatment regimen compared with surgery (p = .0016).

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Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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Role of lifestyle modifications for patients with laryngeal granuloma caused by gastro-esophageal reflux: comparison between conservative treatment and the surgical approach

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Role of lifestyle modifications for patients with laryngeal granuloma caused by gastro-esophageal reflux: comparison between conservative treatment and the surgical approach

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