The effect of metabolic syndrome on Bell’s palsy recovery rate

Abstract

Objective: This study investigated the effects metabolic syndrome (MetS) and its factors such as diabetes mellitus (DM), hypertension (HTN), obesity, hypertriglyceridemia (high TG) and low high-density lipoprotein cholesterol (low HDL-C) on the recovery rate of patients with BP.

Methods: The medical records of 124 patients with BP were retrospectively reviewed. Patients were divided into a MetS group and a Non-MetS group according to the diagnostic criteria of MetS, and the demographic and clinical characteristics of the two groups at baseline and six months after BP onset were analyzed.

Results: Age was significantly higher in the MetS group than in the Non-MetS group (p < .05), but there were no significant differences in sex ratio, initial House–Brackmann (H–B) grade, initial electroneurography and initial electromyography (p > .05). The most common comorbidity of BP was high TG, followed by low HDL-C, HTN, obesity and DM. There were no differences in initial H–B grade in patients with and without each component of the MetS (p > .05). The recovery rate of BP was significantly lower in the MetS than in the Non-MetS group and was particularly affected by DM, obesity and high TG.

Conclusions: Recovery rate op BP is lower in patients with than without MetS.

Chinese abstract

目的：本研究旨在探讨代谢综合征（MetS）及其因素如糖尿病（DM）、高血压（HTN）、肥胖、高甘油三酯血症（TG）和低HDL-C 对BP患者的恢复率的影响。

方法：回顾性分析124例BP患者的病历资料。根据MetS诊断标准, 将患者分为MetS组和非MetS组, 分析两组患者在基线和发病后6个月的人口学特征和临床特征。

结果：MetS组年龄明显高于非MetS组（p < 0.05）, 但两组间的性别比例、初始House-Brackmann（H-B）分级、初始电刺激和初始肌电图（ p > 0.05）并无显著差别。 BP最常见的合并症是高TG, 其次是低HDL-C、HTN、肥胖和DM。 没有或具有MetS组分的患者的初始H-B分级无差异（p > 0.05）。代谢综合征患者血压恢复率明显低于非代谢综合征患者, 尤其是受DM、肥胖和高TG的影响。

结论：有MetS的患者的BP恢复率 低于无MetS的患者。

Keywords:

• Metabolic syndrome
• Bell’s palsy
• recovery rate
• prognosis
• diabetes mellitus (DM)
• hypertension (HTN)
• obesity
• hypertriglyceridemia
• dyslipidemia

Ethical approval

The study protocol was approved by the institutional review board of Kyung Hee University Medical Center. All analyses were based on existing data that has been anonymized; therefore patient’s consent was not required.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2011-0030072).