Reflux symptom index and reflux finding score in 91 asymptomatic volunteers

Abstract

Background: The primary goal of this study was to investigating the symptoms, in addition to the reflux-related laryngopharynx inflammation performance of asymptomatic, volunteers, and verified the ‘normal point’.

Methods: A total of 91 asymptomatic subjects were recruited for this cross-sectional study between March 2016 and September 2016. Participants completed the reflux symptom index (RSI) assessment and underwent laryngostroboscopic examination using a rigid endoscope. Their RFS were graded according to the laryngeal findings. The distribution and the relationship of the RSI and the RFS were analyzed.

Results: The mean RSI of individuals was 2.24 ± 2.34 [95% confidence interval (CI) = 1.75, 2.72], and the mean RFS of individuals was 5.78 ± 1.74 (95% CI = 5.42, 6.15). The Pearson product–moment correlation coefficient of the RSI and RFS scores was –0.084 (n = 91, p = .428).

Conclusions: Asymptomatic people could present relatively high RFS scores, and no linear relationship existed between RSI and RFS.

Chinese abstract

背景：本研究的主要目的是调查除了反流相关喉咽炎症表现之外的无症状志愿者及经验证的“正常点”的症状。

方法：在2016年3月至2016年9月期间, 共有91名无症状受试者被纳入此项横向研究。参与者完成了反流症状指数（RSI）评估, 并接受了使用硬性内镜进行的喉镜检查。根据喉部结果对他们的RFS进行分级。分析了RSI和RFS的分布和关系。

结果：个人的平均RSI为2.24 ± 2.34 [95％置信区间（CI）= 1.75, 2.72], 并且个人的平均RFS为5.78 ± 1.74（95％CI =5.42,6.15）。 RSI值和RFS值的Pearson积矩相关系数为-0.084（n = 91, p = 0.428）。

结论：无症状患者可能表现相对较高的RFS值；RSI和RFS之间不存在线性关系。

Keywords:

• Asymptomatic volunteers
• laryngopharyngeal reflux
• reflux finding score
• reflux symptom index

Additional information

Funding

This research was supported by the Social Development Key Programme of Fujian Province under Grant [number 2016Y0014] and the Medical Elite Cultivation Program of Fujian, China under Grant [number 2014-ZQN-ZD-3].