Risk factors for decannulation failure after single-stage reconstruction of adult post-intubation tracheal stenosis: 10-year experience at a tertiary center

Abstract

Background: Although the risk factors for decannulation failure have been discussed in the literature, there are many unclear points on this issue.

Aims and objectives: To identify risk factors for developing decannulation failure after single-stage surgical reconstruction of post-intubation tracheal stenosis (TS).

Material and methods: A total of 45 adult patients with post-intubation TS admitted to our institution and underwent single-stage surgical reconstruction between April 2008 and May 2018. Nine patients developed decannulation failure by postoperative 6 months (Failed Decannulation Group), and 36 patients were decannulated successfully (Successful Decannulation Group). Causal factors of intubation were noted. Patient-related risk factors of decannulation failure were compared between two groups.

Results: Failed Decannulation Group had a significantly higher body mass index (p = .034) and were more likely to have diabetes (p = .025). Patients who were previously intubated for more than 48 h (p = .043) were significantly more likely to have decannulation failure. The presence of comorbid diseases did not place a patient under statistically significant risk of decannulation failure.

Conclusion: Patients with high body mass index, the ones with diabetes, and patients who were previously intubated for more than 48 h were more likely to develop decannulation failure.

Chinese abstract

背景：尽管文献中已经有关于拔管失败的危险因素的讨论, 但在这个问题上仍有许多不明确之处。

目的：探讨气管插管后狭窄（TS）单期重建术后拔管失败的危险因素。

材料与方法：2008年4月至2018年5月, 我院共收治45例成人气管插管后TS患者, 进行单期手术重建。术后6个月发生拔管失败9例（拔管失败组）, 拔管成功36例（拔管成功组）。注意到插管方面的起因。比较两组拔管失败的患者相关危险因素。

结果：拔管失败组的体重指数（p = 0.034）明显高于对照组（p = 0.025）。先前插管超过48小时（p =0 .043）的患者更容易发生拔管失败。共病的存在并没有使患者面临统计上显著的拔管失败风险。

结论：体重指数高的患者、糖尿病患者和插管时间超过48小时的患者更易发生拔管失败。

Keywords:

• Tracheal stenosis
• decannulation failure
• laryngotracheal stenosis
• risk factors

Acknowledgments

The English in this document has been checked by at least two professional editors, both native speakers of English.

Disclosure statement

No potential conflict of interest was reported by the authors.