Clinical characteristics of otogenic lateral sinus thrombosis in patients under 18 years old compared with that in adult patients

Abstract

Background

Otogenic lateral sinus thrombosis (OLST) is a rare complication of otitis media. We do not know whether the disease progress between the pediatric and adult OLST patients is consistent. However, pediatric surgical methods always refer to the adults'.

Aims/objectives

This study aimed to seek evidence for suitable surgical methods in pediatric patients.

Materials and methods

The clinical manifestation, laboratory findings, and findings in operation between children and adult groups were compared.

Results

Ten children and 17 adults OLST patients were included. Most pediatric patients had no history of chronic otitis media or cholesteatoma (p<.001). The ratios of otorrhea, tympanic perforation and sclerotic type mastoid in CT scan were significantly lower in the children group (p<.05). The mean air conduction hearing threshold in the children and adolescent group (31.25 ± 21.27 dB) was significantly lower than that of the adult group (77.6 ± 23.66 dB) (p<.001). The diseases in attics (66.7%) and the ossicular chain destruction (33.3%) were not as severe as those in the adult group (p<.05). The eustachian tube closure was found similar in two groups.

Conclusions and significance

Conservative surgery is recommended to pediatric OLST to obliterate the diseases and improve middle ear and mastoid drainage, preserving hearing function.

Chinese abstract

背景：耳源性侧窦血栓形成（OLST）是一种罕见的中耳炎并发症。我们不知道小儿和成人OLST患者之间的疾病进展是否一致。但是, 儿科手术方法总是参照成年人的。目的：本研究旨在寻找适合儿科患者的手术方法的证据。

材料和方法：比较儿童和成人组的临床表现、实验室检查结果和手术结果。

结果：本研究包括10名儿童和17名成人OLST患者。大多数儿童患者没有慢性中耳炎或胆脂瘤的病史（p <.001）。耳漏、鼓膜穿孔和硬化型乳突的比率在儿童组中明显较低（p <.05）。儿童和青少年组的平均气导听力阈值（31.25±21.27 dB）明显低于成人组的平均气导听力阈值（77.6±23.66 dB）（p <.001）。中耳顶部的病变（66.7％）和听骨链损坏（33.3％）不如成人组的严重（p <.05）。两组咽鼓管闭合相似。

结论与意义：建议对小儿OLST患者进行保守手术, 以消除疾病, 改善中耳及乳突引流, 保持听力功能。

Keywords:

• Otogenic lateral sinus thrombosis (OLST)
• clinical characteristics
• pediatric and adult
• conservative surgery

Disclosure statement

The authors declare that there is no conflict of interest. There was no financial support or funding during the preparation of this article.