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Original Articles

Studies on the Organophosphorus Insecticides

Part VI. Development of New Low Toxic Organophosphorus Insecticides
Part VII. Chemical and Biological Properties of New Low Toxic Organophosphorus Insecticide. O, O-Dimethyl-O-(3-methyl-4-nitrophenyl) Phosphorothioate

, , , , , , & show all
Pages 597-610 | Received 28 Mar 1961, Published online: 09 Sep 2014
 

Abstract

During the course of investigation on organophosphorus insecticides, many organophosphorus compounds having methyl-, methyl-chloro-, methyl-nitro-, methyl-cyano-, methyl-thiocyano-, methoxy-nitro-, acyloxy-nitro-, and chloro-cyano-phenyl groups were prepared and their biological activities tested. As the results of these studies, two compounds were found as new low toxic organophosphorus insecticides, namely, O,O-dimethyl-O- (3-methyl-4-nitro-phenyl) and O,O-dimethyl-O- (4-cyanophenyl) phosphorothioates.

Abstract

In the previous paper, it has been reported that O,O-dimethyl-O- (3-methyl-4-nitrophenyl) phosphorothioate (commercial name, Sumithion) has not only an extremely low toxicity but also a superior activity towards insects, compared with any other isomers, homologues and analogues. In this paper, the chemical and the biological properties of Sumithion will be reported in detail.

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