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Food and Nutrition

Biochemical Studies on Fatty Liver

Part II. Effects of Amino Acid Supplements on Fatty Liver

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Pages 484-490 | Received 28 Jan 1963, Published online: 09 Sep 2014
 

Abstract

The effects on the fat content in livers of amino acid supplements to various cereal diets at 1.12% dietary nitrogen level, which causes fatty livers in young rats, have been investigated. When rats are fed on diets supplemented with amino acid to retain the requirement pattern of essential amino acids, they grow very well, but the accumulation of liver fat fails to decrease. However, when a part of the requirement pattern diets is replaced with 0.30% of l-threonine, the deposition of liver fat shows a clear decrease. The results obtained suggest that this excess part of threonine has a specific action for the prevention of fat deposition in livers regardless of protein utilization, together with the so-called “supplementary effects” of amino acids.

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