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Abstract
Order of the toxicities of the various cobalt complexes to E. coli B were as follows: Co2+ ≫ [Co(C2O4)3]3− > [Co(NH3)6]3+ > [Co(en)3]3+, [Co(edta)]−, [Co(CN)6]3− = control. The toxicities of the complexes are enhanced under a magnesium-free condition. On the other hand, the uptake of cobalt by cells are ordered as follows: [Co(NH3)6]3+ >[Co(en)3]3+ >Co2+, Co(acac)3, [Co(dip)3]3+ >[Co(edta)]−, [Co(C2O4)3]3− >[Co(CN)6]3−. In this system, the uptake of Co2+ is energy-linked, and dependent on the magnesium existent, while that of [Co(NH3)6]3+ does not show these characteristics. The strong affinity of [Co(NH3)6]3+ to the membrane was observed.