Studies Directed Toward the Synthesis of Optically Active Prostaglandins and Brefeldin A from Carbohydrate. I Synthesis of Optically Active Cyclopentanes from Carbohydrate

Abstract

Optically active trisubstituted and tetrasubstituted cyclopentanes, with proper functional groups of proper stereochemistry as precursors for chiral synthesis of brefeldin A and prostaglandins, were prepared stereoselectively from carbohydrate.