Abstract
A chamber has been designed which delivers a massive inhalation dose to anesthetized animals in a short period of time. The chamber consists of a vertically mounted cylinder with exposure ports arranged so that only the animals' heads are in the dust cloud. Studies have been undertaken exposing Albino rats to strontium and rare earth oxides in the chamber. Data indicate that reproducible chamber concentrations are achieved, and that uniform pulmonary deposition of test material proportional to exposure time is accomplished.