Abstract
The “USPHS” method for determination of lead in air and biological samples has been developed and tested over a quarter of a century. Complete details of procedure are presented with associated information on sampling, preferred method of ashing, purification of reagents, and other preparative procedures. An evaluation of the method for lead in blood shows mean recovery of 97.1% of lead. Among replicate analyses the coefficient of variation ranged from 4.0% to 9.5% for samples respectively containing from 0.291 to 0.020 mg Pb/100 gm blood.