Abstract
The measurement of 2,5-dichlorophenol in urine as a metabolic product of p-dichlorobenzene was studied in relation to its usefulness in industrial exposures to p-dichlorobenzene. The chlorinated phenol was steam-distilled from, acidified urine and determined colorimetrically with 4-aminoantipyrine, and alternatively by extraction of the distillate with hydrocarbon solvents and analysis by ultraviolet absorption. Exposures in various industrial plants handling p-dichlorobenzene were correlated with urinary dichlorophenol excretion at the end of the work shift.
