Abstract
This paper reviews past and recent experiments which have greatly expanded the body of pathotoxicological knowledge on elemental fluorine. The physiochemistry of fluorine reactions with animal proteins and lipids was considered. Toxicity data on short-term animal exposures were compiled, normalized, and correlated with human data. The significance and application of several types of toxicity limits were discussed, and values for emergency exposure limits (EEL), emergency tolerance limits (ETL), and threshold limit values (TLV) were suggested. These values were EEL — 25.0 ppm for 5 minutes; ETL — 15.0 ppm for 10 minutes; and TLV = 1.0 ppm for 8 hours.