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Original Articles

Arterial Venous Blood Levels of Chloropentafluoroethane: Inhalation versus Oral Exposures

Pages 269-275 | Published online: 04 Jun 2010
 

Abstract

The purpose of this work was to correlate a previous 90-day inhalation exposure to chloropentafluoroethane (fluorocarbon 115) with feeding exposures. Whereas 2 to 3 /zg/ml of the fluorocarbon was observed in blood for both 10-minute and 6-hour inhalation exposures at 10% (v/v), a detectable level (>0.06 μg/ml) of the fluorocarbon in the blood was not established for a single 12-gm oral dose of the fluorocarbon. It was concluded that inhalation, of fluorocarbon 115 causes a much higher concentration of fluorocarbon in the blood than that achieved by ingestion.

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