Flame Atomic Absorption Spectrometry Assay for Copper Determination in Pharmaceutical Products for Veterinary Use

Mihaela Scripcariu Institute for Control of Biological Products and Veterinary Drugs, Bucharest, Bucharest, Romania

Ion Gh. Tănase Faculty of Chemistry, Department of Analytical Chemistry, University of Bucharest, Bucharest, Romania

Şerban Fleschin Faculty of Chemistry, Department of Analytical Chemistry, University of Bucharest, Bucharest, Romania

Vasile Magearu Faculty of Chemistry, Department of Analytical Chemistry, University of Bucharest, Bucharest, Romania

Andrei A. Bunaciu CROMATEC PLUS SRL, Analytical Research Department, Bucharest, Romania

Professor Hassan Y. Aboul‐Enein Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo, 12311, EgyptCorrespondence[email protected]

Abstract

The scope of the present study is to quantify copper in pharmaceutical products of veterinary use, using flame atomic absorption spectometry (f_AAS). The determination is carried out after samples' mineralization in a HCl:HNO₃ (20∶1, v:v) mixture followed by the instrument quantification and the validation of the result. The validation indicates that the interferences from the whole analytical system and their measurement do not influence the results and ensure that there are no other effects which have not been considered.

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Flame Atomic Absorption Spectrometry Assay for Copper Determination in Pharmaceutical Products for Veterinary Use

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Flame Atomic Absorption Spectrometry Assay for Copper Determination in Pharmaceutical Products for Veterinary Use

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