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CLINICAL ANALYSIS AND ANALYTICAL BIOCHEMISTRY

A Creatinine Specific Enzyme Electrode

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Pages 1607-1624 | Received 22 Oct 1950, Accepted 05 Nov 1980, Published online: 06 Dec 2006
 

Abstract

An extremely specific creatinine electrode was successfully developed for selective analysis of aqueous creatinine with a linear response over the range from 5 mg/l to 100 mg/l. The endogenous and exogenous species generally present in the serum do not interfere in the assay with the exception of ammonia. With the use of the electrode serum samples containing high creatinine can be assayed directly after pre-treatment. However, the electrode is not sensitive enough to detect the normal level serum creatinine due to the dilution of the serum after treatment.

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