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Analytical Letters Volume 14, 1981 - Issue 20
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PHARMACEUTICAL ANALYSIS

Naproxinate Ion Specific Electrode Development And Use

E. R. Hogue Syntex (U. S. A.) Inc, 3401 Hillview Ave., Palo Alto, CA, 94304
&
W. C. Landgraf Syntex (U. S. A.) Inc, 3401 Hillview Ave., Palo Alto, CA, 94304
Pages 1757-1766 | Received 18 Sep 1981, Accepted 29 Sep 1981, Published online: 05 Dec 2006
 
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Abstract

A unique detector for a specific ionic drug has been fabricated. This sensor has been used to quantitatively determine naproxen in either tablet or capsule form. Detector sensitivity for naproxinate ion was ≤ 10−5 M. with very good selectivity in the presence of most inorganic ions. Assay times were short and appeared amenable to automation.

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