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Abstract
In the present method Isoniazid (INH) has been determined volumetrically using N-bromosuccinimide. INH was taken in aqueous medium and titrated against standard N-bromosuccinimide using Bordeaux Red as indicator. the end point was taken as distinct yellow. the relative standard deviation was 1.5% when 0.5 mg INH was analysed. A number of pharmaceutical preparations were also taken and their INH contents were determined both by this as well as standard method. It was observed that NBS method was more convenient, accurate, precise and rapid.