164
Views
2
CrossRef citations to date
0
Altmetric
Sensors

Detection of Human Growth Hormone (hGH) via Cyclodextrin-Promoted Fluorescence Modulation

&
Pages 1871-1880 | Received 24 Aug 2020, Accepted 21 Sep 2020, Published online: 07 Oct 2020
 

Abstract

The ability to detect human growth hormone (hGH) via sensitive, selective, and easy-to-use methods is a high priority research area from a variety of public health, law enforcement, and scientific objectives. Reported herein is the use of cyclodextrin-promoted fluorescence modulation of a high-quantum yield BODIPY fluorophore in the presence of low concentrations of hGH, leading to a system that can detect hGH in concentrations as low as 0.279 µM and with a 96% accuracy in distinguishing different hGH concentrations.

Additional information

Funding

Funding in support of this research was provided by the Rhode Island Foundation through their Clean Competition Fund.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.