Electrochemical Detection of Dopamine Using a Prussian Blue Carbon Nanotube Composite Decorated with Agglomerated ZnO Particles

Abstract

A Prussian Blue (PB) zinc oxide (ZnO) nanoparticle carboxylic acid-functionalized multiwalled carbon nanotube (PB/ZnO/COOH-MWNT) composite was fabricated for the determination of dopamine (DA). ZnO nanoparticles were tethered to COOH-MWNTs using sonication. Upon attachment of the PB to the ZnO/COOH-MWNTs, which consisted of ZnO nanoparticles 13 nm in diameter, the ZnO coalesced to larger clusters with an average diameter of 573 ± 4 nm. The current response versus various concentrations of DA was measured using chronoamperometry. The optimum conditions for DA measurements were at pH 7.0 using the oxidation current. The sensor has a linear dynamic range from 10 to 900 μM with a limit of detection of 0.37₈ ± 0.01₅ μM, suitable for practical neuroblastoma screening at the lower concentration range and process controls for polydopamine synthesis at the upper concentration range, important for modifying polymeric membranes for water purification.

Keywords:

• Carbon nanotube
• dopamine
• electrochemical sensing
• Prussian Blue

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.