21
Views
4
CrossRef citations to date
0
Altmetric
CHEMICAL AND BIO-SENSORS

Oxygen Electrode With Pyrolyzed CoTMPP Catalyst: Application in Glucose Biosensor

, &
Pages 503-514 | Received 05 Sep 1996, Accepted 23 Oct 1996, Published online: 21 Aug 2006
 

ABSTRACT

Amperometric oxygen sensors employing non-platinum electrocatalyst made from pyrolyzed cobalt-tetramethoxy-phenylporphyrin (CoTMPP) are described. A technique for the preparation of an oxygen working electrode with catalyst from a pressed matrix (tablet) is presented. This technique allows manufacturing numerous electrodes from the same pressed tablet, all of which demonstrate good reproducibility of their parameters. Glucose biosensors are constructed using this oxygen electrode as a basic transducer for amperometric detection of oxygen consumption. The enzyme (glucose oxidase) is held in a micro-bioreactor (face side closed by a Silastic coated polycarbonate membrane) in which the oxygen sensor is immersed. Linearity of the sensor response to glucose concentrations up to 16 mM is reported. Sensors demonstrated a stable signal (varying within ±5% of its average value) during 15 days of continuous in vitro glucose monitoring at 37°C.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.