Determination of Free Aromatic Amines in Radiodiagnostic Preparation using Segmented Flow Analysis

ABSTRACT

A flow-through method for the determination of free aromatic amines in radiodiagnostic preparation was developed. The concentration range of determination, sensitivity of measurement, limit of detection and determination, and repeatability of measurement were found. The method was tested for the analysis of the compound Iodipamide.

Keywords::

• aromatic amines
• diazotization and coupling
• flow-through method
• spectrophotometric detection