Analytical Method Development and Validation for the Academic Researcher

INTRODUCTION

During the course of our scientific careers, and after reading numerous original research papers and reviews submitted for publication to various journals or books, it has become apparent to us that many, if not most, academic researchers have little use for method validation studies or demonstrations. Now, that may sound a bit harsh or a strong way to start this mini-review, but this situation has been our collective impression after carefully reading and commenting on hundreds of submitted journal manuscripts over perhaps the past 25 years.