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Abstract
Unusually severe outbreaks of sarcoptic mange occurred among a total of 559 sheep in the Sudan. The lesions consisted of thick fissured scab on the lips, muzzle, bridge of the nose and outer surfaces of the pinnae. Similar lesions on the flanks, backs and buttocks are recorded for the first time.
The lesions on the lips and muzzle interfered with feeding and drinking and resulted in anaemia, emaciation and sometimes death.
The thick scab seen in advanced cases prevented satisfactory treatment of the condition with coumaphos, hexachlorocyclohexane (benzene hexachloride) and Odylen (Mesulphen: 2,7- dimethyl thianthrene).
Severe histopathological changes were seen in skin sections: acanthosis, hyperkeratosis, scab formation, severe degenerative changes, infiltration with macrophages, eosinophils and lymphocytes, and marked proliferation of the connective tissue.