Serum and erythrocyte concentrations of chloroquine in patients with acute diarrhoea

Abstract

Twenty-three patients with acute diarrhoea were each given a single dose of 300 mg chloroquine base; serum and erythrocyte concentrations were then analysed after one day and four days. Comparisons were made with 11 healthy volunteers. No differences were observed between the different groups, indicating that acute diarrhoea does not decrease the absorption of chloroquine.