Epidemiology of Blastocystis hominis infection in Papua New Guinea: age-prevalence and associations with other parasites

Abstract

A community-based study of Blastocystis and other intestinal parasites in the Asaro Valley, Papua New Guinea showed an extraordinary high prevalence and variety of protozoan infections. Apart from infants, nearly everybody had at least one infection, and the mean number of infections per person was around 2·7. The graph of age-specific prevalence for Blastocystis is similar in shape to those for Entamoeba coli and Endolimax nana, indicating probable similarity in transmission patterns and host response. There was no evidence for pathogenicity of Blastocystis at the community level. Three methods are compared for the measurement of association between infections. Two show strong associations, but these are considered to be the result of parallel age-prevalance curves and environmental factors at the village level. When age- and village-matched pairs were considered, only a weak positive association with E. nana was detectable.