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Abstract
The authors conducted a survey during 1992 to evaluate blood levels of lead and mercury in Inuit adults of Nunavik (Arctic Québec, Canada). Blood samples obtained from 492 participants (209 males and 283 females; mean age = 35 yr) were analyzed for lead and total mercury; mean (geometric) concentrations were 0.42 μmol/l (range = 0.04–2.28 μmol/l) and 79.6 nmol/l (range = 4–560 nmol/l), respectively. Concentrations of omega-3 fatty acid in plasma phospholipids–a biomarker of marine food consumption–were correlated with mercury (r = .56, p < .001) and, to a lesser extent, with blood lead levels (r = .31, p < .001). Analyses of variance further revealed that smoking, age, and consumption of waterfowl were associated with lead concentrations (r 2 = .30, p < .001), whereas age and consumption of seal and beluga whale were related to total mercury levels (r 2 = .30, p < .001). A significant proportion of reproductive-age women had lead and mercury concentrations that exceeded those that have been reportedly associated with subtle neurodevelopmental deficits in other populations.
