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Abstract
This study comprised 112 lead workers, free from apparent disease except that wlhich may be due to lead exposure, and 20 workers in the control group. Of 112 workers exposed to lead, 19 showed significant reduction in the α1-α2-globulin fractions and increased proteinuria due to glomerular lesions, except for three cases with tubular proteinuria. The more the reduction in serum α1-α2-globulin fractions, the greater the increase in proteinuria and coproporphyrinuria.