Tumors of the Respiratory Tract Induced by Inhalation of Bis(Chloromethyl)Ether

Sidney Laskin Institute and Department of Environmental Medicine and the Department of Pathology, New York University Medical Center, New York

Marvin Kuschner MD Institute and Department of Environmental Medicine and the Department of Pathology, New York University Medical Center, New York; State University of New York at Stony Brook, Health Sciences Center, Department of Pathology, Stony Brook

Robert T. Drew PhD Institute and Department of Environmental Medicine and the Department of Pathology, New York University Medical Center, New York; National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

Vincent P. Cappiello MS Institute and Department of Environmental Medicine and the Department of Pathology, New York University Medical Center, New York

Norton Nelson PhD Institute and Department of Environmental Medicine and the Department of Pathology, New York University Medical Center, New York

Abstract

Squamous ceil carcinomas of the lung and esthesioneuroepitheliomas of the olfactory epithelium were produced in high incidence in rats following inhalation of 0.1 ppm of bis(chloromethyl)ether. These findings imply a significant potential occupational hazard.

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Tumors of the Respiratory Tract Induced by Inhalation of Bis(Chloromethyl)Ether

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Tumors of the Respiratory Tract Induced by Inhalation of Bis(Chloromethyl)Ether

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