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Abstract
The lead concentration in 191 normal brains and nine brains from brain tumor patients was determined by the atomic absorption method. The brain samples were obtained from four Chicago area hospitals, and only the right frontal lobes were analyzed. The mean value obtained from the normal brains was 0.50±0.68 ppm (wet tissue). A sharp increase was found in the cerebral lead concentration only during the first two decades of life. There was neither a significant relationship between disease categories obtained at autopsy and the lead concentration in the brain, nor a significant difference in lead values in samples from the different hospitals.
The analyses of the non-neoplastic brain samples from brain tumor patients gave a value of 0.34±0.03 ppm (wet value), which did not differ statistically from that obtained from the normal brains.