Evidence for a Neuromuscular Disorder in Methylmercury Poisoning

Clinical and Electrophysiological Findings in Moderate to Severe Cases

Hussain Rustam MD Department of Neurology, College of Medicine, University of Baghdad, Iraq

Rudolph Von Burg PhD Department of Pharmacology and Toxicology, University of Rochester, New York

LaMan Amin-Zaki MD Department of Pediatrics, College of Medicine, University of Baghdad, Iraq

Sami El Hassani MD Department of Pediatrics, College of Medicine, University of Baghdad, Iraq

Abstract

Data suggestive of a neuromuscular disorder responsive to neostigmine was uncovered in the course of electrophysiological testing of Iraqi patients poisoned by methylmercury.

Subsequent neostigmine therapy produced a remarkable clinical improvement of the patients. Placebo substitution resulted in a substantial loss of testable strength that was restored when drug therapy was resumed.

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Evidence for a Neuromuscular Disorder in Methylmercury Poisoning

Clinical and Electrophysiological Findings in Moderate to Severe Cases

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Evidence for a Neuromuscular Disorder in Methylmercury Poisoning

Clinical and Electrophysiological Findings in Moderate to Severe Cases

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