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Abstract
1. Changes in catecholamine concentration after periods of restraint up to 48 h in male Japanese quail have been measured.
2. Hypothalamic catecholamines decreased after 10 min restraint. Dopamine concentration increased after 4 h and persisted to 48 h.
3. Plasma catecholamines increased after 10 min, remained high for 2 h and then decreased despite continuing restraint. Catecholamine content of adrenals slightly decreased during restraint.
4. The activity of adrenal phenylethanolamine‐N‐methyl transferase increased from the 4th hour of restraint.