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Forty five specimens of Calomys laucha (Olfers, 1818) from Uruguay and Argentina localities, were analyzed. A diploid number 2n; = 64:NF = 68 was found. Heterochromatic blocks were located in the centromeric regions. G-banding pattern and distribution of silver stained material (NORs) were also examined. Analysis of spermatogenesis stages was performed doing emphasis on the sex chromosome behavior.
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